Effect of intravesical and intraureteric pressure on the rate of urinary flow.
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Animals↗
Biomedical subjects
N Shukla
Publications and source records attributed to N Shukla.
Primary gastric plasmacytoma.
A rare case of primary plasmacytoma of the stomach is reported. The diagnostic value of gastroscopy leading to non-surgical management is highlighted. Radiation therapy is an effective alternative mode of treatment and should be employed as the primary modality of therapy.
Aged↗
F-response studies in neonates, infants and children.
F-response has been found to be useful in the evaluation of peripheral nerve conduction in adults and may be especially useful in paediatric nerve conduction studies. In newborns, the nerve conduction velocity is very slow compared to adults because of immaturity of myelination. To assess the effect of age on F-response in 20 neonates, (1 to 28 days), infants (1 mo- 1 y) and children (2-12 y), motor nerve conduction velocity of median, peroneal; sensory conduction velocity of median and F-response from abductor pollicis brevis (APB) by stimulation of median nerve at the wrist were evaluated. The nerve conduction velocity in the neonates was nearly half of that in children and was significantly related to age. F-minimal latency (F-min) showed biphasic distribution; in neonates it was 17 ms, in infants 15 ms and in children 16 ms. The amplitude of F-response was higher compared to infants and children (P less than 0.001). H-reflex in ABP was elicited in all neonates and 55% of infants, its mean latency was 17.9 ms and 15.7 ms respectively. Long latency and high amplitude of F-response and presence of H-reflex in ABP in neonates and infants are due to the immaturity of the nervous system and should be kept in mind while interpreting F-responses in newborns.
Age Factors↗
Peripheral action of angiotensin II.
The effects of angiotensin II were studied on isolated atrial preparations of nonreserpinised and reserpinised rabbits, before and after treating the preparations by propranolol. Peripheral action of angiotensin was cardioaccelerator via direct stimulation of beta-receptors of the atria in isolated atrial preparations.
Angiotensin II↗
Some observations on pulmonary function tests in rice mill workers.
A study was carried out to determine the effects of rice husk dust on pulmonary functions in Rice mill workers. The study population consisted of 150 male Rice mill workers from 6 Rice mills with 50 controls of similar age, sex, ethnic group and agricultural work background. Twenty eight Rice mill workers showed obstructive, whereas eight workers showed restrictive type of pulmonary impairment. The results show that the duration of exposure of Rice husk dust is the workers is related to the degree of decline in FVC, FEV1, FEV3, PEFR and MVV. This could be attributed to allergic inflammatory reactions of pulmonary tissue due to Rice husk dust.
Adult↗
Effect of raised portal venous pressure on blood pressure, urine output and body fluids.
Acute rise of portal venous pressure resulted in a fall of blood pressure and subsequent anuria which could be either due to the state of shock or may be reflex in origin. There also occurred an increase in extra-cellular fluid volume with an initial increase in both plasma volume and interstitial fluid volume. Subsequently the extra-cellular fluid volume remained at a high steady value whereas the plasma volume increased at the expense of interstitial fluid volume which decreased. It is further postulated that the rise of extra-cellular fluid volume is due to the shift of fluid from intra-cellular compartment of the extra-cellular compartment, as a defence mechanism to combat the state of shock.
Animals↗
Study of heart rate and blood pressure changes under distension of right and left atrial appendages in dogs.
Fifteen healthy stray dogs of both sexes were employed in the present study. The effect of distension of right and left atrial appendages with normal saline was observed on heart rate and blood pressure under different situations. It has been found that distension of either appendages separately or simultaneously invariably evoked tachycardia without any appreciable change in blood pressure. Increase in heart rate was found to be of a same magnitude with 5 ml normal saline in both the atrial appendages. However, a higher response was obtained with 10 ml normal saline distension in case of right atrial appendage as compared to left one. Increase in the extent of distension causes more significant response, the receptors of which are stimulated and may be allied to stretch receptors. It is contended that tachycardia could be a reflex effect which is abolished by vagotomy. It is further contended that either afferent, efferent or both pathways exist in the vagi.
Animals↗