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Biomedical subjects

N Sterescu

Publications and source records attributed to N Sterescu.

At least 19 recordsLinked to original sources
PubMed1975

Some aspects of ACTH action on cerebral metabolism in infant rats.

In 150 newborn rats of either sex the influence of ACTH on cerebral phospholipid, phosphoprotein, and nucleic acids metabolism was investigated. The results show that ACTH induces a great stimulation of the cerebral phospholipid metabolism, especially in 14-and 21-day-old rats, a significant increase in the phosphoprotein metabolism at 7 and 14 days after birth, and a stimulation of the RNA synthesis in 7- and 14-day-old rats. The significance of these results is discussed.

Adrenocorticotropic Hormone↗
PubMed1975

Early cold training in newborn rats and dynamics of brain biochemical maturation.

The aim of the experiment was to investigate the influence of cold training in early postnatal life, on the dynamics of some biochemical brain parameters. Studies carried out on 96 Wistar newborn rats led to the following conclusions: chronic exposure to -12 degrees C, 10 min. daily, starting with day 1, or 7, 14, 21, and 30 days induces a significant stimulation of 32P-incorporation into brain phospholipids (in 14-, 21-, and 30-day-old rats), into phosphoproteins, cerebral DNA and RNA (especially in 14-day-old-rats.) The authors discuss the biological significance of these findings.

Acclimatization↗
PubMed1975

Influence of heat exposure on the cerebral metabolism in infant rats.

Studies carried out on 96 Wistar newborn rats led to the following conclusions: the chronic exposure to heat (+40 degrees C), 10 min. daily, starting with day 1, induces a significant stimulation of 32P-incorporation into brain phospholipids (in 7-, 14-, and 21-day-old rats), into phosphoproteins (especially 14 days after birth), and into RNA and DNA (during the first 3 weeks after birth). The hypothalamic 32P-uptake is enhanced in 7- and 14-day-old rats. The authors discuss the biological significance of these findings.

Age Factors↗
PubMed1975

Heat adaptation patterns in infant rats during the first postnatal period.

In 129 infant rats divided into two groups housed to a constant ambient temperature of 21 degrees C, dynamics of body temperature and hypothermic reaction were studied. Beginning with day 1, the experimental group (66 animals), was exposed 15 min. daily for four weeks to an ambient temperature of +40 degrees C. Rectal temperature, temperature of hair-covered skin areas and tail temperature were monitored in either group. A statistically significant difference, which increased with age, between rectal and skin temperature, was found in experimental 3-week-old rats, while in control animals only in 45-day-old ones. Moreover, rectal and skin temperatures in the experimental group were significantly higher than in control group. The body-temperature difference between the two groups disappeared 17 days after cessation of exposure to heat. The hypothermic reaction induced by an weekly 2-min exposure to an ambient temperature of -1 degrees C, was significantly more important and extensive, in the experimental group than in the control one, during the first week of life only. The changes observed suggested a retarded development of the pituitary-corticoadrenal axis.

Acclimatization↗