Biomedical subjects

N T Kuridze

Publications and source records attributed to N T Kuridze.

3 recordsLinked to original sources

PubMed1990

[Axial shift of erythrocytes in arteries supplying blood to the cerebral cortex].

In experiments with rabbits the widths of the axial flows of erythrocytes and of the parietal plasma layers were assessed in pial arterial ramifications supplying the cerebral cortex after their in vivo and in situ fixation under conditions of control and vasodilatation. A strict proportional relationship was revealed between the width of red cell flows and the diameter of pial arteries of 15-200 microns wide. However, the relative plasma volume in the microvessels below 50 microns in diameter was comparatively greater than in the larger vessels. The obtained results prove the feasibility of assessing the microvessels' diameters in tissues where one can see the red cell flow but the vascular walls are invisible. One of the reasons for the lower hematocrit in smaller blood vessels as compared to the larger ones was also elucidated.

Animals↗

PubMed1989

[Features of physiologic mechanisms regulating microcirculation in the cerebral cortex of birds and mammals].

The responses of pial arteries to increased activity of the cerebral cortex as well as their innervation at various stages of phylogenic development, were studied with the aid of serial photomicrography with subsequent frame-to-frame analysis in adult rabbits and hens. Following the application of 0.5% isotonic strychnine solution to brain surface, the dilatation of all the segments of the pial artery ramifications was considerably more obvious in rabbits than in hens. The latencies of the vascular responses differed in a similar way. Histochemical studies revealed a considerably richer adren- and cholinergic innervation in rabbit pial arteries as compared with those of hens. The vascular responses and the neurogenic control of the pial arterial bed seem to become steadily refined, together with its anatomy, in the course of evolutionary development.

Animals↗

PubMed1984

[Structural and functional units in the pial microvascular system].

A study was made of the pial arterial microcircles formed upon successive branching and anastomosing of the terminal pial vessels on the brain cortex surface at different levels of the phylogenetic development of the vertebrata. It was discovered that the pial arterial microcircles progressively become more complicated in the following order: chicken, rabbit, cat, dog, monkey. The morphological signs of the microcircles undergo progressive development: 1) they are formed primarily from small pial arterial branches possessing high vasomotor activity; 2) the area of each circle becomes less and less and their amount per unit of the brain surface increases respectively; 3) the quantity of the feeding arterial branches rises despite the reduction of the circle size; 4) the number of outgoing precortical and radial arteries entering the brain cortex increases; 5) the areas of the brain cortex supplied by individual radial arteries become less and less. This ensures increasingly delicate regulation of adequate blood supply of the smallest areas of the brain cortex.

Animals↗