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Biomedical subjects

N Taverni

Publications and source records attributed to N Taverni.

12 recordsLinked to original sources
PubMed1993

New joint imaging tools in osteoarthritis. I--Validation and preliminary experience with GGGS treatment.

In the pathology of joints, the main aim is an early diagnosis. In osteoarthritis (OA), where laboratory support is particularly poor, traditional radiology is informative only when the pathologic process is so advanced that prevention is difficult, either by changing life habits or by treating with chondroprotective drugs. Therefore an ideal diagnostic imaging tool should be sensitive, specific, reproducible and not invasive. In our opinion, Nuclear Magnetic Resonance (NMR) has all these characteristics and in particular can show meaningful pictures of cartilage and subchondral bone. We therefore compared NMR and traditional radiology to the gross pathology shown by arthroscopy at an early stage of OA, before and after treatment with glycosamino-glucuron-glycan-sulphate (GGGS) or placebo. Our results suggest that NMR is quite meaningful and can detect early OA joint modifications. With this technique the placebo-treated OA patients showed a natural increase in their pathologic picture, while the GGGS-treated patients seemed to experience a retardation in the progression of the disease.

Aged↗
PubMed1989

Computed tomography, magnetic resonance imaging and pathological correlations in a case of Binswanger's disease.

The results of 3 computed tomography (CT) examinations carried out over a 7 year period and of a post-mortem magnetic resonance (MR) study showed aspects of a white matter disease in a hypertensive patient suffering from vascular dementia. Histopathology revealed the primary cause of dementia to be a white matter degeneration sparing the U fibers. Rarefaction of both the myelin sheaths and the axons was present together with severe thickening of the medullary arteries. These findings support the existence of Binswanger's disease (BD) as a distinct variety of arteriosclerotic dementia. CT and MR imaging are valuable aids for diagnosis. However, since there are many other causes of CT and MR demonstrated diffuse white matter degeneration in the elderly, a conclusive diagnosis of BD requires pathological confirmation.

Dementia, Vascular↗
PubMed1988

[Magnetic resonance imaging in the study of brain changes due to carbon monoxide poisoning].

Five cases of carbon monoxide intoxication were studied with MR imaging. The main MR findings were discussed and compared with CT results. MR imaging demonstrated SNC lesions sooner and better than CT--its images corresponding to the anatomic-pathological patterns described in literature. However, severe MR limitations--i.e., the very long execution time and the difficult monitoring of the patients--prevent this methodology from being more extensively employed in this kind of pathology.

Accidents, Home↗
PubMed1987

[Multiple primary tumors of the colon].

Nine cases of multiple primary carcinomas of the large intestine are reported in order to emphasize the importance of an accurate pre-operative search of the other neoplastic lesions after a first cancer diagnosis. As the multiple carcinomas are often in various growing stages it is necessary an accurate X-ray examination for the early cancer diagnosis. It can be concluded that all "at risk" patients (including those already treated by surgery) must be yearly controlled by radiological and endoscopic examinations to assure the best long-term results.

Adult↗
PubMed1985

[Double-contrast with insufflated barium-meal technic in the routine radiological study of the esophagus].

The results are reported of the esophagus double contrast examination with "Insufflated Barium Meal" technique as first part of the routine upper digestive system radiological examination. This technique gives good double contrast without those artifacts using effervescent powders and without modifying the normal radiological alimentary tract examination established way. The double contrast is administered by a special container with a built-in mouthpiece which allows the simultaneous ingestion of barium suspension and air. The esophageal mucosa can be examined as far as the distal tract where frequently the barium contrast stops using different techniques. Good results in 90% of patients have been obtained. The early detection of inflammatory and tumoral lesions has taken particular advantage in patients sometimes asymptomatic.

Air↗
PubMedDate not supplied

MR imaging in a case of Hallervorden-Spatz disease.

Magnetic resonance using a 0.5 T system and a T2-weighted spin-echo pulse sequence revealed symmetric areas of marked hypointensity of the globi pallidi in a case with a family history of and presenting with clinical features consistent with Hallervorden-Spatz disease. No such findings were seen in any of 16 normal volunteers of similar age. Magnetic resonance may be useful for diagnosing Hallervorden-Spatz disease.

Adult↗
PubMedDate not supplied

Cardiac-gated phase MR imaging of aqueductal CSF flow.

The direction of CSF flow within the cerebral aqueduct was studied by cardiac-gated magnetic resonance (MR) phase images in five healthy volunteers and 10 patients with presumably normal cerebral CSF circulation. Caudal CSF flow was observed during systole and cranial flow during diastole. Using phantom based calibrations of the imager, aqueductal CSF velocities of 3-5 mm/s were calculated. Cardiac-gated phase MR is a potentially major tool for the investigation of the CSF circulation.

Adult↗
PubMedDate not supplied

[Nuclear magnetic resonance study of oculomotor alterations in multiple sclerosis].

The authors employing N.M.R. have studied 18 patients affected by M.S. with oculomotor alterations. In 16 cases a relation between location of the lesions and clinical features has been documented; in 2 cases with subclinical paralysis N.M.R. has not documented macroscopic lesions in the brainstem: the presence of multiple lesions in the cerebral white matter however is indicative of supranuclear centers involvement.

Adolescent↗
PubMedDate not supplied

[Magnetic resonance study of lesions of the cervical spinal cord in multiple sclerosis].

Lesions consistent with demyelinating plaques were retrospectively identified in the cervical spinal cord of 15/49 patients (31%) with multiple sclerosis examined with cranial and cervical MR imaging. The lesions appeared as hyperintense areas on proton-density and T2-weighted images. Clinical signs and symptoms suggestive of spinal cord location of the demyelinating plaques were observed in 14 of the 15 patients presenting with spinal cord lesions at MR, and also in 11 of the 34 patients with negative MR findings. In 2 patients the cervical lesion was not associated with brain lesions at MR, while in 1 patient it was associated with medullary dilatation. Serial MRs revealed disappearance of the cervical hyperintense area in both patients, and reduction in medullary volume in the latter. Therefore, MR imaging of the cervical spinal cord is suggested as an useful examination in patients with suspected multiple sclerosis, particularly in those presenting with clinical signs and symptoms suggestive of spinal cord involvement.

Adult↗