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Biomedical subjects

N Toufic

Publications and source records attributed to N Toufic.

At least 19 recordsLinked to original sources

[A new microfilaricide in the therapeutic arsenal of the ophthalmologist].

With no doubt the Ophthalmologist in Tropical African country is the practician most needed for ocular disorders which are precursors of blindness by onchocerciasis or loasis. So, he has to be well-informed concerning each new product able to bring a better efficacy in the treatment of his patients suffering from one or two of these endemic filariasis. He has to know as well how to use it perfectly to experiment it if needed. Ivermectine, MECTIZAN patented, is nowadays the microfilariacide most tolerated in human medicine and is very easy to use in mass therapeutic campaigns as it is easy to administer: one oral dose is available for at least six months. This work deals with the structure of this new anti-parasitary, its quite particular action mechanism, its quite easy dosage, its use precautions and possible contraindications. By this, each practicioner has not to wait an important medical advertisement on this product which is being tested to know the basic points on it and to know how to get it for a possible experimentation for a point of information.

Blindness↗

[Launching of mass treatment of onchocerciasis].

Ivermectine, MECTIZAN patented, is a new anti-parasitic product with wide spectrum, is an efficient microfiliar destructive, and is well tolerated by human being struck down by onchocercosis (filariasis which affects badly local populations in the endemic centres). The launching of a therapeutic mass campaign in North Cameroon in 1987, at an onchocercosis centre located in Sahel savanna (Vina Valley) provides more precise methodology to be used in the field and provides the analysis of the results already obtained; these results seem to be favourable both on parasitologic and ophthalmologic point of view. A new epoch begins, that way, mainly for ophthalmologists and also for all practitioners desirous to fight against onchocercosis which is both a gruesome scourge and a health problem in Black Africa.

Cameroon↗

[Ultrasonography and computed tomography in ophthalmological practice: comparative value during exploration of the eye and orbit (author's transl)].

Ultrasonography is a completely harmless method of examining the eye and the orbit and uses light, inexpensive equipment, within the reach of any ophthalmologist, to provide excellent information concerning the eye and is also well adapted to orbital examination. Cephalic computed tomography, which uses ionizing radiation, is especially efficient in orbital investigations, but this kind of examination is only required in about 10% of cases. It requires expensive, cumbersome equipment and highly specialised staff; frequent use of this method, as well as the injection of contrast products, can be risky. The reader will find 3 tables that summarize briefly the comparative possibilities of ultrasonography and computed tomography in bulbar and orbital investigations and for biometry. A 4th table underlines the suitability of one method or the other in terms of the symptomatology. Consultation of this table could be a time-saver: the ophthalmologist would always begin with the method most likely to give the best information and not waste time doing both. As far as the globe and the orbit are concerned, ultrasonography is normally sufficient. When this method seems problematical or gives insufficient information, the investigation can easily be completed with a computed tomography. Using this method, therefore we can go some way towards limiting the irradiation of the crystalline lens (sometimes unjustified) and towards saving time and money within the Health Service.

Cephalometry↗

[Possibilities and limits of echographic examination of retinal detachment before and after surgery].

Ultrasonography can provide priceless information about a retinal detachment when the fundus is invisible because of a cataract or an unclear vitreous. The exploration of an eye with A-scan ultrasonography is a long and careful procedure which is made step by step along the meridians, then along the parallels of the eyeball. Quantitative ultrasonography is necessary to separate the echoes of the vitreous opacities and of the detached retina. The B-scan gives the same information - except the biometric data - in a much shorter time and is now available without the interposition of water between the patient and the probe. It also permits an easy diagnosis of the choroidal detachment. After the operation, when the media are not clear, A-and B-scan ultrasonography can give an early indication of whether the retina is reattached or not. But at that time a mistake may be made due to the edge of buckling and everyone should be aware of this.

Humans↗