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Biomedical subjects

N V Dmitrieva

Publications and source records attributed to N V Dmitrieva.

At least 73 records · Page 4Linked to original sources
PubMed1980

[Biphasic action of caffeine on contractile activity of frog myocardium].

Action of caffeine on the isometric contractions and intracellular potentials of the frog heart muscle involved the positive inotropic effect only at high concentrations (0.1-20 mM). The "dose-action" curve for the twitch responses reached plateau at caffeine concentration higher than 4 mM. Two phases of the caffeine effect on the frog myocardium contractility were identified: transient increase of the contraction amplitude (the 1st phase) was followed by the inhibition of contractions and shortening of the APs (the 3nd phase). The magnitude of the contractile changes and the duration of each phase depended on the caffeine concentration.

Action Potentials↗
PubMedDate not supplied

[Attitude of population and physicians to the organization of medical care in a city].

The authors analyze the population self-estimations of the health status and opinions on the quality of services rendered at local health centers, attitude to medical care, and suggestions on improvement of medical service organization. Analysis of interviews with physicians showed their attitude to transfer from state public health to medical services with different types of property and their opinions on modern situation in public health management. The priority problems of public health and potentialities of improving the activities of treatment and prophylactic institutions of the city and the quality of services rendered to the population have been identified.

Adult↗
PubMedDate not supplied

[A symmetrical approach to the analysis of cardiocyte electrical and contractile activity].

Based on the systemic symmetrical approach, experimentally determined parameters of action potential and contractile response of frog myocardial strip were analyzed prior to and after the administration of several physiologically active drugs (caffeine, neoepinephrine, nembutal, ouabain) into the perfusate. It was shown that the satisfactory functional state of preparation was characterized by an interrelation between parameters in the form of a harmonic proportion with relatively constant coefficient. When the functional state of subject is affected by a physiologically active substance, the interrelation between the parameters is considerably changed. Based on the analysis of the data of literature, it was found that the interrelation between temporary parameters of action potential in various structures from human heart has the form of a harmonic proportion with a constant coefficient close to the invariant of "Gold Wurf" proportion. The similarity is underlined of principles of cardiac function temporary arrangement at levels of cell, organ and organism.

Action Potentials↗
PubMedDate not supplied

[The status of indices of immunity and hemostasis in patients with lung cancer and their changes due to general anesthesia and surgical trauma].

Phagocytosis, some factors of humoral immunity and hemostasis have been studied in cancer patients before and after surgery. Suppression of natural body resistance in the preoperative period, as well as significant inhibition of leukocyte phagocytic activity following surgery and anesthesia have been established. A correlation has been suggested between hemostasis damages in the postoperative period and an elevated IgM concentration.

Anesthesia, General↗
PubMedDate not supplied

[Low-molecular peptides in food as factors altering the resistance of rats to emotional stress].

The authors studied the resistance of animals to emotional stress when they were given in the diet, as a source of protein, casein and a protein fraction composed of a mixture of amino acids and low-molecular peptides (18 and 2.7%) obtained by reprocessing Saccharomyces cerevisiae yeasts, biomass. The ECG, rheovasogram, systolic arterial pressure, and respiratory rate were studied in rats given a diet containing 18 and 2.7% low-molecular peptides (controls) and in the same animals after 24-hour immobilization. Addition of low-molecular peptides in the indicated concentration to the diet reduced the resistance of animals to emotional stress.

Animals↗
PubMedDate not supplied

[The resonance phenomenon in the human cardiorespiratory-hemodynamic system].

The ratio of the period of cardiac cycle to the period of vessel autofluctuations is constant in healthy resting humans. This ratio constitutes 1.309 +/- 0.068. The same correlation is observed between the duration of the pneumo-cycle and the period of respiratory arrhythmia. At working and post-constriction hyperemia, there is a resonance in cardiac-respiratory-hemodynamic system that synchronizes the fluctuation processes of its constituent elements and increases the RVG amplitude. The data obtained have been discussed.

Adult↗
PubMedDate not supplied

[The symmetry approach to the assessment of the functional state of the human body].

A multiparameter description of different functional states of human organism has been accomplished on the basis of clinical and polymetric study of healthy and ill humans. The analysis of multiparameter data has been carried out using symmetry approach, image recognition, and graphic simulation. A harmonic correlation between complex physiological parameters of cardiovascular, respiratory, and vegetative nervous system is characteristic for healthy humans. The harmonic correlation changes by 10-15% in humans under stress and by more than 15% in ill humans. The intersystem interaction of physiological functions has been described.

Adult↗