PubMed Health⌕ Search

Biomedical subjects

N V Kudrina

Publications and source records attributed to N V Kudrina.

5 recordsLinked to original sources
PubMedDate not supplied

[The intensity of cell receptor catabolism in intestinal yersiniosis and pseudotuberculosis].

The intensity of the catabolism of cell receptors in yersiniosis was evaluated by the level of R-proteins in the blood sera of 95 patients. The study revealed that the degree of an increase in the level of R-protein depended on the severity and the course of the pathological process was the same in both nosological forms of the disease. The high and stable level of R-proteins was indicative of the possibility of the prolonged and relapsing course of yersiniosis.

Blood Proteins↗
PubMedDate not supplied

[The role of the complement system in the pathogenesis of yersinioses].

In 95 patients with Yersinia infections (yersiniosis and pseudotuberculosis) the character of changes in the complement system was studied, taking into account the functional activity of C1-C5, Co. The study demonstrated a decrease in the activity of the complement system in the dynamics of Yersinia infections and revealed quantitative changes of characteristics in yersiniosis and pseudotuberculosis. The results of the study suggest the mobilization of the complement system in Yersinia infections by the classical path of activation. Regularities of changes in the activity of C1-C5, Co, corresponding to the severity and clinical variants of Yersinia infections, make it possible to recommend the use of the above-mentioned parameters in the clinic of infectious diseases for evaluating the effectiveness of treatment and the course of the disease.

Complement System Proteins↗
PubMedDate not supplied

[Immune complexes and R-proteins in yersinioses].

The intensity of the catabolism of cell receptors in yersiniosis patients has been studied. The dynamics of R-protein level reflects the relapsing character of the pathological process irrespective of the presence of clinically pronounced relapses and the form of the disease. The concentration of circulating immune complexes is elevated during the whole course of the disease and does not depend on its gravity and clinical form. The spectrum of immune complexes in the blood sera of yersiniosis patients is heterogeneous and changes in the course of the disease.

Antigen-Antibody Complex↗
PubMedDate not supplied

[Collective immunity to diphtheria in the children and adolescents of Vladivostok during a mass immunization against this infection].

The state of collective immunity to diphtheria in children and adolescents of Vladivostok was studied. Adsorbed DPT vaccine was shown to have higher immunological effectiveness in comparison with adsorbed DT toxoid with reduced antigen content. As revealed in this study, as early as in 2 years a part of the children lost their immunity, irrespective of the preparation used for vaccination, and enlarged the reserve of initially seronegative children and adolescents, capable of maintaining the epidemic process of diphtheria.

Adolescent↗