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Biomedical subjects

N V Leneva

Publications and source records attributed to N V Leneva.

9 recordsLinked to original sources
PubMed1988

[Biological effects of leakadin].

57 patients with disseminated tumors of various sites received 10 daily doses of 600 mg/m2 leakadin intravenously. The immunostimulating effect was observed (OKT4/OKT8 normalization). The data on leakadin pharmacokinetics are discussed.

Adjuvants, Immunologic↗
PubMed1980

[Interferon production during interaction between lymphocytes and L cell targets in different stages of the mitotic cycle].

Interferon is observed in culture medium in interaction of L-target cells (synchronized in the G1 and S phase and unsynchronized) with lymphocytes (intact, immune and actinomycin D-treated). Interferon production is induced after 30 min (20--25 units/ml) of interaction between immune lymphocytes and L cells in the G1 phase, reaches the maximum after 10 hours (70--75 units/ml) and slightly decreases after 48 hours (60--65 units/ml). In interaction of both immune and actinomycin D-treated lymphocytes with L cells in the G1 and S phase, interferon production correlates with the cytotoxic lymphocyte effect on these cells.

Animals↗