PubMed Health⌕ Search

Biomedical subjects

N V Novikova

Publications and source records attributed to N V Novikova.

At least 19 recordsLinked to original sources
PubMed1979

[Fluoride contents of rat molars following the administration of amine-fluoride-containing caries preventives (author's transl)].

Experiments on fifty Wistar rats were conducted with the object of studying the incorporation of fluoride into the enamel of molars subsequent to the administration of amine-fluoride-containing caries preventives. - Use of two toothpastes with low fluoride contents of 0.125% and 0.18% F, respectively, and two higher-fluoride (1% F) solutions resulted in a marked increase in the concentration of fluoride in the superficial layers of dental enamel.

Animals↗
PubMed1979

The sympatho-adrenal system and sulfhydryl groups in the heart in experimental myocardial infarction.

In 59 sexually mature male chinchilla rabbits, and in control sham-operated animals, there were compared the indicators characterizing the functional state of the heart and the levels of catecholamines and of SH groups in experimental myocardial infarction induced by ligating the descending branch of the left coronary artery. Phasic shifts were found in the heart adrenergic regulation, dependent on the stage of infarction. In all animals in the acute stage of myocardial infarction the activity of the sympatho-adrenal system was enhanced. In an extensive transmural infarction and in cases with a lethal outcome the levels of total and protein-bound noradrenaline were lowered. The course and prognosis of experimental myocardial infarction were dependent on the degree of disturbance of formation of complexes of noradrenaline with adrenoreceptor structures, caused by decreases in the levels of noradrenaline and sulphydryl groups.

Adrenal Glands↗
PubMed1976

[Blood proteins, thiol group metabolism and testosterone content in prostatic dysfunction].

A study was made of the blood serum proteins, thiol groups, aldolase activity, testosterone content in rabbits under conditions of insufficiency of the prostate gland caused by its suturing. It was revealed that at the late postoperative periods there was an increase in the blood serum proteins of albumin fraction, and a reduction of the thiol group level (SH-free, masked and disulfide). Aldolase activity increased at the early periods and then sharply fell. The incretory function of the testes was disturbed.

Animals↗
PubMedDate not supplied

[A comparison of the effect of tranquilizers in experiments and clinical practice].

Experimental and clinical study of the analgesic effects of mebicar and benzodiazepine series tranquilizers (sibazon and chlozepid) and their combinations with non-narcotic analgesics (amidopyrin, pyranal) or local anesthetic lidocaine has demonstrated a more marked effect of benzodiazepine derivatives on pain sensitivity thresholds as against mebicar. Tranquilizer combinations with other analgesics helped define the optimal premedication variants: benzodiazepine derivative augment analgesic activity whereas mebicar potentiates lidocaine effect.

Adolescent↗