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Biomedical subjects

N V Putov

Publications and source records attributed to N V Putov.

At least 19 recordsLinked to original sources
PubMed1998

[Clinical and experimental aspects of pulmonology].

The prevalence of lung diseases and its associated sociomedical losses remain to be intolerable. The advantages of Russia's existing outpatient pneumonia treatment are shown. Experimental and clinical data on the polyetiology of acute respiratory distress syndrome and positive experience with extracorporeal detoxification, various efferent treatments and auxiliary membrane oxygenation of blood are given. The current approaches to interpreting, treating, and preventing chronic pulmonary obstructive diseases, bronchial asthma, emphysema, interstitial (disseminated) lung diseases and mucoviscidosis are discussed.

Animals↗
PubMed1990

[The etiology of acute pneumonia].

Based on the results of the authors' own investigations and the reported data it is shown that primary (extrahospital) acute pneumonia (AP) is of pneumococcal etiology in the overwhelming majority of patients. At the same time in 2/3 of cases, AP is associated with influenza and other acute respiratory virus infections. If primary AP runs an unfavourable course, a secondary infectious inflammatory process induced by different opportunistic bacteria may occur. The secondary (intrahospital) APs developing in the presence of marked disorders of the total and local defence are polyetiologic in nature. This is often caused by the association of a number of causative agents belonging to the families of different aerobic and anaerobic bacteria and by a change of etiological factors in the course of the disease. Gram-negative enterobacteria, Pseudomonas and nonsporulating obligate anaerobes are the main causative agents of secondary pneumonias as well as of infectious processes that complicate primary APs.

Acute Disease↗
PubMed1990

[Respiratory viral infection and the immune reactivity of patients with different forms of bronchitis].

Virological and immunological examinations made in 258 persons with different forms of bronchitis (acute, relapsing, chronic nonobstructive and obstructive) made it possible to establish a correlation between the forms of bronchitis and the intensity of immunosuppression as well as between the variety and duration of respiratory virus infections, which may indicate that viruses are implicated in the pathogenesis of both acute and chronic processes.

Adolescent↗
PubMed1990

[Changes in the functional state of the adrenal glands in experimental bronchospasm in dogs].

Changes in the adrenal functional state were revealed during the development of bronchoconstriction induced by allergen inhalation in 7 dogs sensitized with ovalbumin. The decrease in V1 (expiratory flow-volume) on an average by 58% was noted after inhalation of 1000 microG of ovalbumin. The significant decrease in II-hydroxycorticosteroids (II-OCS), adrenaline, noradrenaline, dopamine, and a tendency to the increase in histamine content were observed in the venous blood plasma. The decrease in the adrenaline content in plasma apparently contribute to the development of early bronchoconstrictor response, and the decrease in II-OCS maintain the development and the progress of late bronchoconstrictor response.

Adrenal Glands↗
PubMed1989

[Current status of the problem of chronic cor pulmonale].

Studies of great number of patients with chronic nonspecific pulmonary disease suggest that high levels of pulmonary hypertension are only observed in cases of pulmonary-arterial thromboembolism and primary pulmonary hypertension. In other pulmonary diseases, the significance of pulmonary hypertension seems to be overestimated, as blood pressure in the pulmonary circulation network has values, indicative of the absence of gross morphologic changes of the vascular bed of the lungs. The available indirect methods for the diagnosis of pulmonary hypertension in chronic nonspecific pulmonary disease patients with rather small blood pressure in the pulmonary circulation network are shown to be of little value. Large functional reserves of the right cardiac ventricle which make it possible to cope with a sudden pressure overstrain (to say nothing of the slowly augmenting one) are pointed out. It follows therefore that either as yet unknown factors contribute to the pathogenesis of chronic pulmonary heart decompensation, or there is virtually no decompensation, while the demonstrated clinical symptoms of systemic circulatory congestion are of extracardiac origin. Various aspects of the assessment of the role of pulmonary hypertension and clinical symptoms of decompensated pulmonary heart will be discussed in the next communication.

Blood Pressure↗
PubMed1989

[Role of the rise of pressure in the pulmonary artery in the distribution of perfusion and gas exchange in bronchial obstruction].

The experiments on the dogs revealed that the damage of lobar bronchus conduction resulted in the decrease of O2 tension in pulmonary venous blood of this lobe. The decrease in the ventilation and blood flow was found in the zone of obstruction by using tracers 133Xe and 99mTc. The pressure rise in the pulmonary artery caused by the spread of bronchial obstruction is one of the factors promoting the redistribution of perfusion into the reserve zones of lungs. The decrease of pressure by the ganglio-blocking preparation results in the increase of arterial hypoxemia.

Animals↗
PubMed1988

[Chronic pancreatitis and alcoholism (the need for continuous treatment)].

It was shown that the absence of the alcoholic treatment was responsible for the deterioration of the patient's condition after the operation for chronic pancreatitis of the alcoholic nature and resumption of taking alcohol. Labour rehabilitation of the patients made up as little as 50%. Psychotherapy and psychopharmacotherapy of alcoholism if performed before and after operation under conditions of specialized hospitals resulted in a considerable improvement of the patients' condition, in better labour and social rehabilitation of patients with chronic alcoholic pancreatitis. Labour rehabilitation in such patients made up 80%.

Adult↗
PubMed1987

[Surgical treatment of primary chronic pancreatitis].

Surgical methods of treatment of chronic alcoholic pancreatitis must be chosen with special reference to the state of the duct and parenchyma of the pancreas. Treatment of alcoholic patients should be performed with the participation of psychiatrists.

Adult↗
PubMed1987

[Effect of a local disorder of bronchial patency on the circulation and gas exchange in the lungs].

Acute and chronic experiments on dogs have demonstrated the onset of local alveolar hypoxia in disturbed bronchial patency. Alveolar hypoxia caused a rise in the pulmonary vascular resistance. Pulmonary hypertension is predetermined by an increased number of pulmonary zones of hypoxic vasoconstriction due to higher incidence and degree of bronchial obstruction. Despite pulmonary circulation redistribution confirmed by radioactive indicator 99mTc distribution, the perfusion of hypoventilated pulmonary regions is retained leading to venous shunt generation and the reduction of oxygen tension in the arterial animal blood.

Animals↗
PubMed1986

[Disseminated processes in the lungs--a current problem of modern pulmonology].

A total of 453 patients with pulmonary disseminations were investigated. A clinico-statistical study of 16,000 adults estimated at 93.7 per 100,000 the prevalence of disseminated pulmonary conditions among the adult population. The referral and clinical diagnoses coincided in 17.4% of cases only, while the time between the emergence of the first symptoms and the final diagnosis averaged 21 +/- 3.3 months. The most valuable diagnostic signs were identified using the association criterion. They were: dyspnea, labored inspiration, hemoptysis, crepitation, spontaneous pneumothorax, roentgenologic evidence of raised diaphragmatic vaults and enlarged mediastinum lymph nodes, as well as certain neutrophil and lymphocyte levels in lavage fluid (Chuprov's coefficient between 0.32 and 0.42). Major management principles are developed with reference to stages of fibrosing alveolitis and granulomatosis.

Adult↗
PubMed1985

[Large-intestinal lesions in destructive pancreatitis].

An acute destructive pancreatitis may be followed by a lesion of the colon with its developing necrosis, narrowing etc. Seven cases with such complications are described. Problems of surgical tactics in patients with a destructive pancreatitis complicated by lesions of the colon are discussed.

Acute Disease↗