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Biomedical subjects

N V Rishko

Publications and source records attributed to N V Rishko.

15 recordsLinked to original sources

[New-onset angina pectoris: clinical aspects, diagnosis, prognosis and treatment tactics].

NOA patients are not a homogeneous population in relation to impairment of coronary circulation, clinical symptoms and prognosis. Early hospitalization and treatment of the disease result in more favourable hospital and long-term responses than in the overall population of coronary patients. Conservative and surgical treatment in them produce almost similar results as regards survival and incidence of acute myocardial infarction. Hence, it is thought justifiable to use drugs in the majority of NOA patients leaving surgery only for patients with grave multiple coronary lesions and resistance to chemotherapy.

Angina Pectoris↗

[Prognosis of conservative and surgical treatment in angina pectoris at the onset].

Altogether 130 patients with angina pectoris of new onset have been examined. Besides the routine cardiologic methods of examination, bicycle exercise, 24-hr ECG monitoring, selective coronary arteriography, and left ventriculography have been employed. In cases with clinical symptoms of coronary artery spasms the ergometrine test has been used and, if positive, repeated during arteriography. Surgical treatment (direct revascularization of the myocardium) has been administered to 49 patients, 81 patients have been treated conservatively. The prediction has been studied both at the prehospital stage and in late periods of the follow-up. Surgical treatment significantly increased the survival rate of angina pectoris patients with impaired myocardial function (the ejection fraction under 50%); the clinical course of the disease also improved as compared to that in patients treated conservatively. In the patients with a decent function of the myocardium (the ejection fraction surpassing 50%) the mode of treatment did not essentially influence the survival rate or the possibility of a myocardial infarction both in the immediate and late periods after treatment.

Angina Pectoris↗

[Status of the coronary arteries and possibilities of reconstructive surgery in patients with newly developed stenocardia].

The state of coronary arteries was assessed by means of angiography, and coronary-bed tendency to spastic response was assessed by the ergometrin test in 76 patients with angina of new onset (several days to 2 months since the first symptoms). It is suggested that coronary spasm as well as the rate and extent of development of collateral anastomoses in response to stenosing events in the coronary arteries are as important as the anatomical factor in the pathogenesis of angina. Aorto-coronary shunting is possible in most of such patients.

Adult↗

[Oxygen and hemodynamic provisions for measured physical exertion in ischemic heart disease patients with intact and atherosclerotic coronary arteries].

Cardiorespiratory response to exercise was studied in 111 coronary patients. Resting oxygen and hemodynamic support was not affected in either the patients with atherosclerosed coronary arteries, or those with intact ones. Three types of cardiorespiratory response to exercise were identified--normal, compensated and subcompensated. A possibility of predicting the extent of coronary reserve in coronary patients, without exercise intensified to threshold values, was explored. The pattern of cardiorespiratory response to exercise in coronary patients with intact coronary arteries is described.

Adult↗

[Evaluation of cardiac function in patients with ischemic heart disease in the early stages of controlled physical exercise].

Fifty-nine coronary patients and 20 clinically normal subjects were investigated. Coronarography was performed in 21 patients. Everybody was referred to one of the three functional classes. Central hemodynamic parameters were measured using tetrapolar chest rheography. Venous levels of lactic and pyruvic acids were also measured. The measurements were taken in resting conditions and under threefold increase in systemic oxygen consumption following bicycle ergometry in supine position. Three types of response were identified: normal, compensated and decompensated ones. On the basis of these, functional reserves of the heart can be evaluated at earlier stages of rationed exercise, this being particularly important for coronary patients not to be exposed to maximum and submaximum physical stress.

Coronary Disease↗

[Choice of treatment methods in initial forms of ischemic heart disease].

The authors examined 125 patients with initial forms of ischemic heart disease (duration of no more than 2 months). The examination comprised coronarography, ventriculography, 24-hour ECG monitoring, and bicycle ergometry. The patients were divided into two groups: group 1 consisted of 81 patients who received nonoperative treatment; group 2 was formed of 44 patients who underwent operation for aortocoronary shunting. The results of treatment were appraised according to three parameters: a state of angina pectoris, prevention of myocardial infarction, and survival. They were studied in the hospital stage and in the long-term follow-up periods. Comparative analysis showed that surgery had some advantages over nonoperative treatment in relieving completely attacks of angina pectoris and transitory episodes of myocardial hypoxia. Patients who had been operated on possessed higher tolerance to physical exertion. None of the two methods of treatment had advantages over the other in regards to prevention of myocardial infarction, a fatal outcome, and prolongation of survival.

Coronary Artery Bypass↗