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Biomedical subjects

N V Svechnikova

Publications and source records attributed to N V Svechnikova.

9 recordsLinked to original sources
PubMedDate not supplied

[Urinary aldosterone excretion and erythrocyte and plasma sodium and potassium ion concentration in persons of different ages].

Practically healthy persons (79 in all) aged from 20 to 80 years and over were examined. The work was aimed at the study of the character of aldosterone excretion and its correlation with the ionic composition of erythrocytes and the peripheral blood plasma in persons at various age periods. As revealed, the activity of glomerular zone of the adrenal cortex in persons aged from 20 to 40 years displayed sexual differences: 1.33 times more aldosterone was excreted with the urine in women than in men. With the advance of age there occurred a functional decrease in the glomerular zone of the adrenal cortex. In senile persons (aged 80 years and over) this difference was entirely eliminated. Sodium ions in erythrocytes increased, but remained unchanged in the peripheral blood plasma. Potassium ion concentration fell both in the erythrocytes and in the blood plasma. A reduction of aldosterone content failed to alter the sodium-retention effect of its action which corresponded to the concept on increase of tissue sensitivity to hormones with the advance of age.

Adrenal Cortex↗
PubMedDate not supplied

[Genitography in intersexuality].

Genitography was performed in 60 patients with different sexual abnormalities. The main types of the structure of external and internal genitals were revealed. Genitography can be used in any age, including the 1st year of life. It allows one to take timely measures in determining the civil sex of the infant and early planning the correcting surgery. The data obtained indicate this method to be of interest in the examination of patients suffering from intersexuality.

Adolescent↗
PubMedDate not supplied

[Sex and age differences in the peripheral blood aldosterone levels].

Age-associated and sexual differences in the adrenocortical glomerular zone function of normal subjects were studied by radioimmunoassay. The blood plasma aldosterone content (13.46 +/- 1.18 ng%) of adult females (27) was 20.7% higher than that of the males (22) of the same age (11.15 +/- 0.56 ng%). An increase in the blood aldosterone content in menopause appears to be due to the hyperestrogenic phase (the first menopausal phase in women) and estrogen-stimulated aldosterone synthesis. Sexual differences in aldosterone secretion disappear with age. Aldosterone content is significantly lower in males and females, age over 80 years, than that in younger subjects, and sexual differences are absent.

Adrenal Cortex↗