Biomedical subjects

N Vénissac

Publications and source records attributed to N Vénissac.

4 recordsLinked to original sources

PubMed2006

["Therapeutic" pleural surgery].

Renewed interest in carcinological pleura surgery for the treatment of mesothelioma has resulted from an increased incidence of the tumor and also better control of postoperative mortality for an operation with a dramatic reputation. Techniques include pleurectomy, pleurodecrotication and wide pleuropneumectomy. To achive isolated resection of the parietal pleura or a combined resection of the parietal and visceral pleura with more or less wide resection of the diaphragm and pericardium. Indications depend on the tumor extension and the patient's status. Mortality, particularly for wide pleuropneumectomy is no well controlled by well-trained teams and is to the order of 5%. The rate of local recurrence is to the order of 10% and can warrant use of local treatments such as intrathoracic hyperthermic chemotherapy. Median survival for operated mesothelioma is 19 months with a 46% five-year survival for the tumors with the best prognosis. At the present time, radical surgical resection is the basis of local treatment for pleural mesothelioma.

Chemotherapy, Adjuvant↗

PubMed2006

Can intrapleural C-reactive protein predict VATS pleurodesis failure?

BACKGROUND: Intrapleural inflammatory reaction after surgery for spontaneous pneumothorax is a key indicator whether an effective pleurodesis has been achieved. In this study, we tested the hypothesis that intrapleural C-reactive protein (CRP) might precisely quantify the postoperative pleural inflammation, offering potentially useful information for patient management. METHODS: The study population consisted of 75 consecutive patients who underwent video-assisted thoracoscopic pleurectomy or pleural abrasion for spontaneous pneumothorax between April 2003 and August 2004. We assessed CRP levels in pleural and blood samples taken daily in the first 4 postoperative days. RESULTS: Intrapleural CRP profile was significantly lower in patients who underwent pleural abrasion, in younger patients (< 25 years) and in patients who were not drained before surgery. Patients with pleurodesis failure had a lower CRP peak with a delayed peak. Receiving operating characteristics (ROC) analysis showed that the cutoff value of intrapleural CRP for pleurodesis failure was 25 mg/l on the second postoperative day (sensitivity 87.5 %, specificity 66.6 %, positive predictive value 24.1, negative predictive value 97.7 %). CONCLUSIONS: Pleural CRP levels of less than 25 mg/l on the second postoperative day indicate only a moderate pleural inflammation.

Adolescent↗

PubMed2004

[Unilateral neurogenic pulmonary edema. A case report].

A vascular lesion was identified in the posterior cerebral fossa in a 65-Year-old stroke victim. The patient suddenly developed unilateral pulmonary edema. Bilateral alveolar opacities is the usual radiological aspect of neurogenic pulmonary edema but a unilateral presentation is extremely rare. The differential diagnosis includes excessive vascular filling, infectious pneumonia, gastric fluid aspiration edema, and cardiogenic pulmonary edema. The mechanisms underlying neurogenic pulmonary edema are discussed.

Aged↗

PubMed2000

Recurrent pneumothorax associated with thoracic endometriosis.

Herein we report the cause of a 46-year-old woman who presented with recurrent right pneumothorax following hysterectomy with right salpingo-oophorectomy for pelvic endometriosis. Video-assisted thoracoscopy revealed endometrial implants in the posterior parietal pleura and the middle lobe. Ruptured apical blebs were also present. The middle lobe lesions and the apical blebs were resected. A partial pleurectomy was carried out to remove the endometrial foci in the parietal pleura; the remaining pleural surface was mechanically abraded. The favorable outcome was confirmed at 2-year follow-up.

Endometriosis↗