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Biomedical subjects

N Vyramuthu

Publications and source records attributed to N Vyramuthu.

5 recordsLinked to original sources
PubMed1985

Metastatic carcinoma from unknown primary site: the experience of a large oncology centre.

The case records of patients presenting with metastases from an unknown primary cancer (MUP) have been reviewed. Important prognostic variables were performance status and the presence of disease in more than one system. Patients of poor performance status and disease in multiple organs had a median survival of one month and 87% were dead within three months. Those patients of good performance status and disease apparent in only one organ had a median survival of seven months. Patients with carcinoma confined to lymph nodes in the high cervical region who received treatment with radiotherapy had 3- and 5-year survival rates of 26% and 17% respectively.

Aged↗
PubMed1983

The management of craniopharyngioma.

Twenty-six patients with proven craniopharyngioma were treated between 1954 and 1977. Total surgical removal was achieved in three patients (11.5%). Tumour recurrence was inevitable following incomplete surgical removal alone. Fifteen patients received post-operative radiotherapy following incomplete surgical removal of the tumour and eight patients (54%) survived, recurrence-free, for 5 years or more. Post-operative radiotherapy, delivering a central target absorbed dose of 4500 cGy in 20 fractions over 28 days (1520 rets) or more, significantly improved the recurrence-free survival (P = 0.019) with minimal morbidity. Partial resection of recurrent tumour carried a high mortality rate. Minimal salvage surgery in the form of cyst aspiration sometimes resulted in worthwhile palliation.

Adolescent↗