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N Wakasugi

Publications and source records attributed to N Wakasugi.

49 records · Page 3Linked to original sources
PubMed1981

Studies on blood groups in the Japanese quail: the common antigens possessed by red blood cells and leukocytes, and their inheritance.

Two alloantigens, Ly1 and Ly2, were detected with alloantisera made by immunization with leukocytes. These antigens were present on red blood cells, peripheral leukocytes and spleen cells and found to be controlled by the autosomal codominant alleles. The phenotypic frequencies of Ly1 antigen in the three quail stocks, 1, 2, and 3, were 6.7, 0, and 100 percent, respectively, and those of Ly2 antigen were 0 percent in stocks 1 and 2, 7.1 percent in stock 3. It was suggested that Ly1 and Ly2 antigens might be associated with the system controlling A (QN1) antigen which was originally detected by the natural alloantibody. However, it remains to be investigated whether these antigens are associated with the major histocompatibility complex (MHC) of the Japanese quail.

Absorption↗
PubMed1977

Studies on the development of F1 embryos from inter-strain cross involving DDK mice.

The development of the early mouse embryos was investigated from 36 to 84 h after the presumed time of fertilization. The mean number of cells constituting the embryo from the intra-strain crosses of three strains at 84h of development was as follows: DDK, 22-7; BS, 43-1 and ITES, 62-0. A significance was observed in the cleavage rate of the embryo between DDK and the other two strains. The F1 embryos from the crosses of BS females X DDK males and ITES females X DDK males showed almost the same progress of development as BS and ITES embryos, respectively. Therefore, it is concluded that the early development of the F1 embryos iss, DDK females X BS males, showed conspicuously small cell numbers as compared with their litter-mates that developed to the blastocyst stage. It is inferred that the discrimination is already made during cleavage between the fortunate survivors and the lethal embryos due to the incompatibility between the cytoplasmic factor of DDK eggs and alien spermatozoa.

Animals↗
PubMedDate not supplied

Testicular degeneration induced in rat offspring by maternal treatment with sobuzoxane.

Pregnant rats were orally administered sobuzoxane (an antitumor drug) during various days of gestation and the testicular development of their offspring was examined histopathologically on day 21 after birth. When 15.6 to 250 mg/kg of sobuzoxane was given every day from day 7 to 17 of gestation, seminiferous tubules devoid of spermatogonia and/or spermatocytes were found in a dose related manner. The critical period for testicular degeneration was identified to be day 13 and 14 of gestation by single administration experiments and single treatment with 15.6 to 250 mg/kg of sobuzoxane on day 14 of gestation gave a dose-dependent incidence of the tests abnormality. These results suggest that the testis abnormality in offspring from dams treated with sobuzoxane is due to inhibition of the proliferation of primordial germ cells during testis organogenesis.

Administration, Oral↗
PubMedDate not supplied

Genetic analyses of plumage color mutations on the Z chromosome of Japanese quail.

Genetic analyses were performed with four sex-linked plumage color mutations (roux, brown, imperfect albino, and cinnamon) in Japanese quail (Coturnix japonica). Roux and brown quail have similar plumage color, but plumage of roux quail is paler. Pure, F1 and F2 matings were carried out with roux and brown stocks, and 357, 338, and 273 progeny with either roux or brown plumage color were obtained from each mating type, respectively. These allelism tests showed that mutations for roux and brown colors were alleles (*R and *B) from the same locus BR, and that BR*B was dominant over BR*R. Two alleles at the AL locus, AL*A (imperfect albino) and AL*C (cinnamon) were used to estimate the recombination frequency between the BR and AL loci on the Z chromosome. It was estimated to be 38.1+/-1.0% based on 4615 chicks from the test crosses.

Alleles↗
PubMedDate not supplied

A genetic defect in hyomandibular furrow closure in the Japanese quail: the causes for ear-opening abnormality and formation of an ear tuft.

The mutant ET (ear tuft) quail strain is characterized by an ear-opening abnormality frequently accompanied by ear tufts. The mutant ear opening is oval shaped with a fissure on its ventral margin, whereas the ear tufts project from the ventral end of the fissure or the posterior margin of the ear opening. The ear tufts are composed of a feathered peduncle. The size of the ear tufts and the ear-opening abnormality are variable. The incidence of the ear tufts and the ear-opening abnormality in the ET embryos at 15 days of incubation was 33% and 42%, respectively. Examination of early embryos revealed an incomplete closure of the hyomandibular furrow, the incidence of which was 91% in 5 day embryos. It appears that the hyomandibular furrow abnormality is the primary defect leading to the ear-opening and ear-tuft traits. Genetic analyses of hyomandibular furrow closure defect indicated it to be due to an autosomal recessive mutation. The proposed gene symbol is hfd.

Animals↗
PubMedDate not supplied

Allelism of panda and dotted white plumage genes in Japanese quail.

Panda and dotted white mutant plumage colors of Japanese quail (Coturnix japonica) were found to be controlled by the autosomal alleles. Both mutants showed white plumage with colored spots or patches, but they were easily distinguishable by size and location of the colored areas and the color and markings of the pigmented feathers. At hatching also they were easily distinguishable by the position, size, and colors of the spots or patches. The panda chicks possessed large blackish patches on the head, back, tail, cheek, and wing, whereas the dotted white chicks had small light brown spots on the head and/or back. Some dotted white chicks (12%) did not have any brown spots. In a testcross experiment, panda type and dotted white type progeny segregated in 1:0, 3:1, 1:0, and 1:1 ratios in the F1 and F2 generations and in back-crosses to the panda and dotted white parents, respectively, suggesting allelism and dominance of panda over dotted white. The new gene symbol sdw is proposed for the allele controlling the dotted white plumage.

Alleles↗