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Biomedical subjects

Naeem Raza

Publications and source records attributed to Naeem Raza.

8 recordsLinked to original sources

Secondary syphilis clinically mimicking pseudolymphoma of the face.

Syphilis has been given titles such as the great imitator, the great mimic, and the great masquerader. It may lack pathognomonic signs and often presents similar to many other dermatological conditions. We present a case of a young woman who developed asymptomatic papulonodular lesions on the forehead; the lesions were clinically similar to pseudolymphoma but it was determined that she had secondary syphilis exhibiting prozone phenomenon. She also had alopecia of eyebrows. Both the alopecia as well as nodular lesions clinically resembling pseudolymphoma responded to and completely recovered with antisyphilitic treatment.

Adult↗

Progressive symmetrical erythrokeratoderma with perioral involvement.

Erythrokeratodermas are inherited or sporadic disorders of keratinization, with many variants. Progressive symmetrical erythrokeratoderma presents as large, erythematous or hyperpigmented, hyperkeratotic, fixed symmetrical plaques over various parts of the body along with many other inconsistent features. Periorificial keratotic lesions have very rarely been reported in progressive symmetrical erythrokeratodermas. We report a 9 years old boy with progressive symmetrical erythrokeratoderma having perioral involvement besides fixed hyperpigmented, keratotic plaques. He was started with oral etretinate but he stopped the treatment due to no-response after two weeks and is presently using topical keratolytics without marked improvement.

Child↗

Cutaneous pseudolymphoma due to topical application of 4% hydroquinone cream for melasma.

Cutaneous pseudolymphoma is an aggregate of mature or abnormal looking lymphocytes in the dermis, which clinically and /or histologically simulates lymphoma but has a benign course and outcome. Systemic drugs, especially anti-epileptics, are an important cause of cutaneous pseudolymphomas. Pseudolymphoma of the skin, secondary to topical drug application, is very rare. We report a case of cutaneous pseudolymphoma induced by local application of 4% hydroquinone cream to melasma over the cheeks.

Adult↗

Rickets in xeroderma pigmentosum.

Xeroderma pigmentosum patients are advised to strictly avoid sun exposure to prevent ultraviolet-induced DNA damage. We describe a 2 1/2 years old boy having xeroderma pigmentosum, who also developed rickets. He was given one injection of vitamin D along with dietary vitamin D supplements to which he responded. He is being followed- up regularly in outdoor clinic with the advice to the parents to continue dietary vitamin D supplements and to avoid sun exposure.

Child, Preschool↗

Unilateral psoriasis along Blaschko lines.

Atypical forms and unusual localizations of psoriasis are quite frequently seen. However, psoriasis arranged unilaterally along Blaschko Lines is extremely rare. We report a case of an adult male, who presented with unilateral psoriasis arranged in Blaschko Lines on left side of the body.

Adult↗

Recurrence of herpes zoster in an immunocompetent adult male.

Repeated and disseminated eruptions herpes zoster are frequently detected in immunocompromised patients, but are rare in immuno-competent individuals. We report a case of recurrent herpes zoster in a young healthy male, who redeveloped herpes zoster in a different dermatome after one year.

Acyclovir↗

Simultaneous onset of herpes zoster in a father and son.

The Varicella Zoster virus persists in sensory nerve ganglion cells after chicken pox and gets reactivated to cause herpes zoster after variable periods of time as a result of waning of specific cellular immunity. Susceptible contacts of herpes zoster can develop chicken pox and very rarely herpes zoster. We report an interesting case of a father and his son who developed herpes zoster simultaneously without any obvious common predisposition and discuss the possible underlying mechanism.

Acyclovir↗

Exuberant ulcerated lesions of secondary syphilis on the palms--an unusual presentation.

Ulcerated lesions in secondary syphilis are rare. Exuberant tissue is seen in condylomas of syphilis, which occur in flexural and occluded areas of the body and not in open areas such as palms. We report a case of secondary syphilis that presented with ulcerated exuberant lesions on palms, which on initial examination gave an impression of lesions of Orf and Milker's Nodule.

Adult↗