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Biomedical subjects

Naomi Tanoue

Publications and source records attributed to Naomi Tanoue.

At least 19 recordsLinked to original sources
PubMed2006

[Strategic plan for reshaping and using fixed prosthesis].

Fixed prosthodontics is the art and science of restoring defective or damaged teeth and/or replacing missing teeth. The primary objective of a restoration is to recover functional occlusion. Additionally, patients, regardless of their age and sex, have needs related to esthetic restoration. To please patients, the dentist must deliver an esthetic restoration that blends with the patient's natural teeth. These are some of the needs related to "basic research" in fixed prosthodontics. Either ceramic materials or resin composites are used for indirect esthetic restoration. In general, tooth-colored materials require incremental thicknesses to ensure adequate color and sufficient mechanical properties. However, the thick form of a prosthesis contradicts the concept of "minimal intervention". Patients though require restorations that meet their esthetic needs without any significant loss of tooth structure. The strategy for the "new (advanced) research" in fixed prosthodontics should be based on the two concepts of esthetics and minimal intervention. Although these two factors appear inconsistent, patients unquestionably require both to be provided with high quality care that will include both solutions in the context of a well-organized and sequenced comprehensive treatment plan. Consequently, in response to the growing popularity of esthetic dentistry, we dentists should develop a new dentistry field, one that introduces relevant new technologies along with newly developed materials.

Dental Materials↗
PubMed2006

Effect of metal priming agents on bonding characteristics of an acrylic resin joined to SUS XM27 steel.

The purpose of the current study was to evaluate the effect of functional monomers contained in the primers on adhesive bonding of a steel alloy. SUS XM27 steel was primed with one of the following materials; Alloy Primer, Estenia Opaque Primer, and V-Primer. The functional monomers in the primers were a phosphate (10-methacryloyloxydecyl dihydrogen phosphate; MDP) and a thione (6-(4-vinylbenzyl-n-propyl) amino-1,3,5-triazine-2,4-dithione, -dithiol tautomer; VTD) for Alloy Primer, MDP alone for Estenia, and VTD alone for V-Primer. The steel disks were bonded with an acrylic resin (Unifast Trad), and bond strength was determined. Of the three primers, both the Alloy Primer (33.3 MPa) and Estenia Opaque Primer (33.9 MPa) materials exhibited far better post-thermocycling bond strength than V-Primer (0 MPa). It can be concluded that the phosphate MDP is effective, whereas the thione VTD is ineffective for bonding SUS XM27 steel.

Acrylic Resins↗
PubMed2006

Porcelain laminate veneer restorations bonded with a three-liquid silane bonding agent and a dual-activated luting composite.

This clinical report describes the fabrication and bonding of porcelain laminate veneer restorations in a patient with anterior open spaces. Laminate veneer restorations made of feldspathic porcelain were etched with 5% hydrofluoric acid, rinsed under tap water, ultrasonically cleaned with methanol, and primed with a chemically activated three-liquid silane bonding agent (Clearfil Porcelain Bond). The enamel surfaces were etched with 40% phosphoric acid, rinsed with water, and primed with a two-liquid bonding agent (Clearfil New Bond) that contained a hydrophobic phosphate (10-methacryloyloxydecyl dihydrogen phosphate; MDP). The restorations were bonded with a dual-activated luting composite (Clapearl DC). The veneers have been functioning satisfactorily for an observation period of one year. Combined use of the Clearfil bonding agents and Clapearl DC luting composite is an alternative to conventional materials for seating porcelain laminate veneer restorations, although the system is inapplicable to dentin bonding.

Acid Etching, Dental↗
PubMed2006

Bond strength to primed Ti-6Al-7Nb alloy of two acrylic resin adhesives.

This study aimed to evaluate the bonding behavior of two acrylic resin adhesives joined to titanium-aluminum-niobium (Ti-6Al-7Nb) alloy primed with two metal conditioners. Cast Ti-6Al-7Nb alloy disks were air-abraded with alumina and bonded with six combinations of two resin adhesives (Super-Bond C&B and Multi Bond) and three surface conditions (Alloy Primer, M.L. Primer, and unprimed control). Shear bond strengths were determined both before and after 20,000 thermal cycles. The tri-n-butylborane initiated Super-Bond C and B resin exhibited greater bond strength than the BPO-amine initiated Multi-Bond resin. Both the Alloy Primer with a hydrophobic phosphate and the M.L. Primer with a phosphonoacetate effectively improved the 24-hour bond strength of Multi-Bond resin as well as the post-thermocycling bond strength of Super-Bond C and B resin.

Acid Etching, Dental↗
PubMed2006

Evaluation of 2 thione primers and 3 resin adhesives for silver-palladium-copper-gold alloy bonding.

OBJECTIVE: The purpose of this study was to evaluate 2 thione primers and 3 resin adhesives for enhancement of bonding strength to a silver-palladium-copper-gold alloy. METHOD AND MATERIALS: Two different sized disk specimens (10- and 8-mm diameter by 2.5-mm thick) were prepared from a silver-palladium-copper-gold alloy (Castwell M.C. 12, GC). The specimens were airborne-particle abraded with 50-microm-grain alumina, conditioned either with a thiouracil primer (Metaltite, Tokuyama Dental) or with a triazine dithione primer (V-Primer, Sun Medical), and then bonded with 1 of 3 acrylic resins: a benzoyl peroxide-amine redox-initiated resin adhesive (Multi-Bond, Tokuyama Dental) or a tri-nbutylborane-initiated resin adhesive (Super-Bond C&B and Super-Bond Quick, Sun Medical). For each adhesive, unprimed specimens were prepared as experimental controls. Shear bond strength was determined after thermocycling (100,000 cycles). RESULTS: Use of primers significantly (P < .05) enhanced the bond strength of specimens in all adhesives. Irrespective of the type of primer, the strength of Multi-Bond adhesive was significantly (P < .05) lower than that of Super-Bond C&B and Super-Bond Quick adhesives. The strength of the 2 tri-n-butylborane-initiated adhesives did not differ significantly (P > .05). The mean strength of the Super-Bond C&B adhesive was 40.4 MPa with Metaltite and 37.8 MPa with V-Primer; that of Super-Bond Quick adhesive was 40.9 MPa with Metaltite and 36.5 MPa with V-Primer. CONCLUSION: Use of thione primers effectively enhanced the strength of the bond to the silver-palladium-copper-gold alloy. Furthermore, the combinations of primers and tri-n-butylborane-initiated adhesives were found to be more efficient for bonding.

Air Abrasion, Dental↗
PubMed2005

A pore-forming toxin produced by Aeromonas sobria activates cAMP-dependent Cl- secretory pathways to cause diarrhea.

Aeromonas sobria hemolysin (ASH) is one of the major virulence factors produced by A. sobria, a human pathogen that causes diarrhea. We investigated the effects of ASH on Cl(-) transport in human colonic epithelial cells. ASH increased short-circuit currents (Isc) and (125)I efflux from Caco-2 cells, indicating ASH activate Cl(-) secretion. Additions of inhibitors of cyclic AMP dependent Cl(-) channels, glybenclamide and NPPB suppressed the Isc and (125)I efflux increases induced by ASH. And ASH increased the intracellular cyclic AMP concentration. Moreover, ASH stimulated fluid accumulation in the iliac loop test, and glybenclamide and NPPB suppressed this fluid accumulation. Thus, cAMP-dependent Cl(-) secretory pathway could be related with diarrhea induced by A. sobria.

Aeromonas↗
PubMed2005

A pore-forming toxin produced by Aeromonas sobria activates Ca2+ dependent Cl- secretion.

Bacteria produce many types of hemolysin that induce diarrhea by mechanisms that are not completely understood. Aeromonas sobria hemolysin (ASH) is a major virulence factor produced by A. sobria, a human pathogen that causes diarrhea. Since epithelial cells in the intestine are the primary targets of hemolysin, we investigated the effects of ASH on ion transport in human colonic epithelial (Caco-2) cells. ASH increased short-circuit currents (Isc) in a dose-dependent manner, and it also activated a 125I efflux from Caco-2 cells. ASH-induced Isc increases and 125I efflux activations were both suppressed by low Ca2+ levels in the extracellular solution or by pretreatment with the Ca2+ chlelator BAPTA-AM. Intracellular Ca2+ levels were increased by ASH in a biphasic fashion characterized by a rapid sharp increase (peak 1) followed by a sustained low plateau (peak 2). ASH-induced peak 1 was inhibited by pretreatment with pertussis toxin, indicating that Ca2+ was mobilized from intracellular stores, and peak 2 was induced by an influx of extracellular Ca2+. Peak 2 but not peak 1 was related to Cl- secretion. These results indicate that ASH activates Ca2+-dependent Cl- secretion.

Aeromonas↗
PubMed2005

Use of a light-polymerized composite removable partial denture base for a patient hypersensitive to poly(methyl methacrylate), polysulfone, and polycarbonate: a clinical report.

This article describes a light-polymerized composite denture base used for a patient with hypersensitivity to poly(methyl methacrylate) (PMMA), polysulfone (PSF), and polycarbonate (PC). A urethane-dimethacrylate (UDMA) composite was used as an alternative to fabricate both the denture base and the custom artificial teeth. Immediately after placing the new prosthesis, allergic symptoms disappeared from the patient's mucous membrane. The denture has functioned satisfactorily for more than 2.5 years without recurrence of the hypersensitivity.

Acrylic Resins↗
PubMed2005

[Team communication needed in treatment for fixed prosthesis. 2) Opinion from dental technician's standpoint].

The fabrication of a fixed prosthesis is influenced by the communication between the dentist and the laboratory technician. Especially for tooth-colored restoration of anterior teeth, the laboratory technician has the difficult task of understanding the shade selected by the dentist and reproducing it in the final restoration. Conventional shade analysis techniques using the Vita shade guide often result in subjective analysis and a resultant miscommunication of color. Over the years, many different techniques including picture-taking, drawing of diagrams, and using multiple shade guides have been formulated to help overcome this problem. Recently, digital shade analysis systems have been designed to eliminate the subjectivity of color analysis and provide precise information for laboratory buildup and fabrication. However, even these techniques have not completely erased the difficulties involved in communicating the choice of the proper shade for tooth-colored restoration. Many dentists are only familiar with techniques they were taught in dental school and/or their residency program, and they are unaware of other, superior methods that can be used. This review introduces various shade analysis systems that can be performed in dental clinical practice. Further, it highlights the importance of communication between the dentist, technician, and patient for the fabrication and delivery of aesthetic restorations.

Color↗
PubMed2005

Effect of metal halide light source on hardness, water sorption and solubility of indirect composite material.

This study evaluates the effects of a metal halide light source on the post-polymerization properties of the Sinfony indirect composite material. Two polymerization systems were employed: the Hyper LII system, comprising a metal halide polymerization unit, and the Visio system, comprising two proprietary units designed for polymerizing the Sinfony composite. The composite material was polymerized for 60, 120 or 180 s with the LII system. As a control, the composite was polymerized for 15 min with the Visio system. Knoop hardness, water sorption and solubility were determined. The results were analyzed by Dunnett's T3 multiple comparison test (P<0.05). Knoop hardness was greater for polymerization with the LII unit than for that with the Visio system. Water sorption was greater for polymerization with the Visio system than that with the LII unit. For polymerization with the LII unit for 180 s, solubility was significantly reduced as compared with the Visio system. Within the limitations of the current experiment, it can be concluded that the metal halide unit exhibited better polymerizing performance for the composite material than the proprietary units.

Composite Resins↗
PubMed2005

Effectiveness of bonding systems on bonding durability of a prefabricated porcelain material.

The purpose of the present study was to evaluate the bond strength and durability of four bonding systems joined to a prefabricated porcelain material (Vita Celay Blanks). Two sizes of porcelain block were bonded with one of the following systems: (1) Clapearl Bonding Agent and Clapearl DC; (2) Imperva Porcelain Primer and Imperva Dual; (3) Monobond S and Variolink II; or (4) Tokuso Ceramics Primer and Bistite II. Shear bond strength was measured after 24-hour immersion in water and after subsequent thermocycling. The average pre- and post-thermocycling bond strengths in MPa (n=8) were: 52.5 and 42.5 for bonding system (1), 47.7 and 32.8 for (2), 55.0 and 48.8 for (3), and 51.5 and 25.6 for (4). Although prethermocycling results were not statistically different from each other, Group (3) exhibited the greatest strength after thermocycling.

Analysis of Variance↗
PubMed2005

Properties of an indirect composite material polymerized with two different laboratory polymerizing systems.

The purpose of the current study was to evaluate the performance of two laboratory light polymerization systems used to polymerize an indirect composite (Sinfony). A two-step polymerization system (Visio-Alfa and Beta) and a halogen-metal halide unit (Twinkle MIII) were assessed. The composite was polymerized either with the Visio units or with the MIII unit for different exposure periods. Knoop hardness, water sorption, and solubility in water of the composite polymerized with the following modes were determined: Visio, 15 minutes; MIII, 30, 60, 90, 120, and 180 seconds. Extension of light exposure time to the MIII unit improved the hardness of the composite from 30.5 (30 s) to 40.7 (180 s), whereas hardness obtained with the Visio units resulted in 24.8 (15 minutes). Water sorption and solubility of the composite were greater when it was polymerized with the Visio units than with the MIII unit.

Absorption↗
PubMed2005

A new laboratory polymerizing apparatus equipped with halogen and metal halide light sources.

We developed a new laboratory polymerizing unit (Twinkle MIII: M3) equipped with different light sources (a metal halide and two halogen lamps) that could illuminate independently. This study introduced the structure of the curing unit and examined the curing depth of a representative indirect composite (Artglass). The composite material was cured with the following modes: 1) M3 - halogen only; 2) M3 - metal halide only; 3) M3 - both halogen and metal halide (HM); 4) conventional xenon; and 5) preliminary halogen. The results obtained from analysis of variances and post-hoc tests revealed that curing depth was affected significantly (p < 0.05) by both exposure mode and time, and that HM mode exhibited the most favorable curing performance (p < 0.05) among the curing units and polymerization modes. In conclusion, the M3 unit was found to be well suited to polymerizing the composite material tested.

Analysis of Variance↗
PubMed2005

Twenty-four hour bond strength between layers of a highly loaded indirect composite.

This study evaluated the repair bond strength of Estenia composite. Disk specimens of a dentin material were conditioned with varying combinations of silane primer (Add-on Primer, Clearfil Porcelain Bond Activator, Clearfil Porcelain Bond Activator + Clearfil Mega Bond-Primer, Porcelain Liner M, and unprimed) and bonding agent (Clearfil Mega Bond-Bond, Modeling Liquid, Stain Diluent, and no bonding agent). After photopolymerization of the enamel material placed on each surface, the specimens were either wet- or dry-stored at 37 degrees C for 24 hours. Average shear bond strength varied from 24.9 to 61.4 MPa, where the Clearfil Porcelain Bond Activator + Clearfil Mega Bond-Bond group and the Add-on Primer + Modeling Liquid group showed the greatest bond strength for dry and wet conditions respectively. To achieve reliable bond strength between layers of Estenia composite, it is highly recommended to use specific combinations of silane primer and bonding agent.

Composite Resins↗
PubMed2005

Application of a preliminary light-curing unit for enhanced bonding between a gold alloy and veneering materials.

PURPOSE: To evaluate the effectiveness of a preliminary light-curing unit when it was used in a procedure to bond veneering material to metal. METHODS: Two light-activated composite materials (Artglass and Cesead II) were separately placed onto gold alloy disks (Pontol LFC), and polymerized using one of the following three methods: (1) exposure with a high-intensity laboratory light-curing unit (Hyper LII) for 90 seconds; (2) exposure with a preliminary light-curing unit (Targis Quick) for 20 seconds, followed by exposure with the high-intensity unit for 90 seconds; and (3) exposure with the preliminary unit for 90 seconds, followed by exposure with the high-intensity unit for 90 seconds. Shear bond strengths were determined and compared by analysis of variance and post-hoc multiple comparison intervals. The curing depths of the two materials polymerized with the two curing units were determined using a scraping technique described by the International Organization for Standardization (ISO) 4049 with the aim of evaluating the difference in curing performance between the two units. RESULTS: The group polymerized using the preliminary unit for 90 seconds showed statistically improved bond strengths over the group polymerized without the preliminary unit (P < 0.05) regardless of the materials. Regarding the Cesead II material, both groups polymerized using the preliminary unit also indicated significantly improved bond strength compared with the group polymerized with high-intensity only. Also, curing depth results revealed that the high-intensity unit demonstrated greater curing performance than the preliminary unit for both types of materials examined.

Composite Resins↗
PubMed2004

Localization of the 31-amino-acid endothelin-1 in hamster tissue.

Endothelin (ET)-1(1-31) is a novel vasoconstrictor peptide produced by human mast cell chymase, which selectively cleaves big ET-1 at the Try(31)-Gly(32) bond. We investigated the localization of ET-1(1-31) in various hamster tissues by immunohistochemistry and compared it to the distribution of ET-1(1-21). We found that the localization and amount of ET-1(1-31) were different from those of ET-1(1-21) in each tissue. ET-1(1-31)-like immunoreactivities (IR) in the heart, lung, and adrenal gland were observed in the same areas as ET-1(1-21) but were significantly weaker, suggesting that ET-1(1-31) might play a role only in mast cell/chymase-related pathological conditions in these tissues. In the liver, ET-1(1-31)-like IR was strongly detected in Kupffer cells where ET-1(1-21)-like IR was seen more weakly. In the kidney, ET-1(1-31)-like IR was slightly higher than ET-1(1-21). These results suggest that ET-1(1-31) might have physiological roles distinct from those of ET-1(1-21) in some hamster tissues.

Animals↗
PubMed2004

Influence of acidulated phosphate fluoride solution on the color stability of indirect composites.

STATEMENT OF PROBLEM: Although acidulated phosphate fluoride (APF) agents are known to be useful for caries-preventive interventions, few studies have examined the influence of APF agents on indirect composite materials. PURPOSE: This study examined whether exposure to APF agents affects color stability when a composite is exposed to a common staining agent. MATERIALS AND METHODS: Forty light-polymerized composite disks (8 x 2.0 mm) were fabricated with midifilled (Cesead II; n = 20) and microfilled (Newmetacolor Infis; n = 20) composites. The specimens were polymerized with a light for 90 seconds on each side, ground with silicon carbide paper, finished using a polishing kit, and colorimetrically evaluated to determine baseline L*a *b* values. After storage in distilled water at 37 degrees C for 24 hours, half of the disks for each composite (n = 10) was treated with an APF solution (Fluodent A) for 32 minutes, while the remaining half of the specimens were untreated (controls). Half the treated and untreated specimens were immersed in tea or distilled water (n = 5, respectively), and after 4 weeks color changes were measured. To determine the influence of APF on each composite, the CIE L*a*b* color difference baseline values after 4 weeks were compared using 2- and 1-way analyses of variance and post-hoc Sheffe's S intervals (alpha=.05). RESULTS: The color differences of both materials when immersed in tea were significantly influenced by APF (P < .05). The mean DeltaE values of APF-treated Cesead II and Newmetacolor Infis immersed in tea were 5.4 +/- 1.2 and 4.5 +/- 1.3, respectively, while the untreated values were 3.8 +/- 0.6 and 3.0 +/- 0.1, respectively. When immersed in water, neither material was affected by APF in respect to change in color. CONCLUSION: The color of both composites tested were significantly influenced by APF treatment when immersed in tea, indicating that the in vitro color stability of the indirect composites was negatively affected by applications of APF.

Acidulated Phosphate Fluoride↗