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Biomedical subjects

Nasir Saleem

Publications and source records attributed to Nasir Saleem.

4 recordsLinked to original sources

Congenital pyloric atresia: isolated and associated with aplasia cutis congenita.

Two cases of congenital pyloric atresia (CPA) are, hereby, reported. One was suspected on antenatal ultrasound and turned out to be an isolated anomaly. Other patient had a rare association of aplasia cutis congenita with congenital pyloric atresia. The lesions of aplasia cutis congenita were multiple while congenital pyloric atresia was of type II. The patient with an isolated lesion survived following surgery while the other baby died of sepsis in postoperative period.

Adult↗

Sirenomelia (Mermaid baby).

Sirenomelia is a rare anomaly that rarely occurs as an isolated lesion. Several theories have been proposed regarding the etiopathogenesis. In this communication, we report a case of sirenomelia. Our patient was referred to hospital at the age of four hours. On examination, fusion of both lower limbs with hook shaped appendage, attached distally, absent genitalia and absent anal orifice was found. Spine was deficient in sacral region. Upper torso looked normal. Baby also had frothing from mouth. Abdomen was non-distended. Feeding tube no.10 was tried to pass through mouth, which got obstructed at the level of upper esophagus that suggested oesophageal atresia. The skeletogram revealed absence of pelvic bones, sacral agenesis, absent fibulae and fracture of both femora. The patient died at the age of 12 hours.

Abnormalities, Multiple↗

Meckel's diverticulum causing exsanguinating haemorrhage.

A seven month old male baby presented to emergency room in shock. Patient had 3 hours history of massive fresh bleeding per rectum. Emergency laparotomy revealed Meckel's diverticulum (MD) with large vitello-intestinal artery responsible for massive bleeding. Diverticulectomy was performed.

Gastrointestinal Hemorrhage↗

Rectal prolapse: an unusual presentation of malakoplakia in a child.

A case of a young girl is presented. The main concern was recurrent rectal prolapse not responding to conservative and sclerotherapy. Colonoscopy showed diffuse colitis with superficial ulcerations and pseudopolyps. Colon biopsies finally showed classical features of malakoplakia confirmed by histopathological test. Conservative treatment failed and ultimately proctocolectomy was performed with ileoanal endorectal anastomosis.

Biopsy↗