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Biomedical subjects

Nasser Peyghambarian

Publications and source records attributed to Nasser Peyghambarian.

4 recordsLinked to original sources

Switchable electro-optic diffractive lens with high efficiency for ophthalmic applications.

Presbyopia is an age-related loss of accommodation of the human eye that manifests itself as inability to shift focus from distant to near objects. Assuming no refractive error, presbyopes have clear vision of distant objects; they require reading glasses for viewing near objects. Area-divided bifocal lenses are one example of a treatment for this problem. However, the field of view is limited in such eyeglasses, requiring the user to gaze down to accomplish near-vision tasks and in some cases causing dizziness and discomfort. Here, we report on previously undescribed switchable, flat, liquid-crystal diffractive lenses that can adaptively change their focusing power. The operation of these spectacle lenses is based on electrical control of the refractive index of a 5-mum-thick layer of nematic liquid crystal using a circular array of photolithographically defined transparent electrodes. It operates with high transmission, low voltage (<2 Vrms), fast response (<1 sec), diffraction efficiency > 90%, small aberrations, and a power-failure-safe configuration. These results represent significant advance in state-of-the-art liquid-crystal diffractive lenses for vision care and other applications. They have the potential of revolutionizing the field of presbyopia correction when combined with automatic adjustable focusing power.

Accommodation, Ocular↗

Femtosecond pulsed laser micromachining of glass substrates with application to microfluidic devices.

We describe a technique for surface and subsurface micromachining of glass substrates by using tightly focused femtosecond laser pulses at a wavelength of 1660 nm. A salient feature of pulsed laser micromachining is its ability to drill subsurface tunnels into glass substrates. To demonstrate a potential application of this micromachining technique, we fabricate simple microfluidic structures on a glass plate. The use of a cover plate that seals the device by making point-to-point contact with the flat surface of the substrate is necessary to prevent the evaporation of liquids in open channels and chambers. Methods for protecting and sealing the micromachined structures for microfluidic applications are discussed.

Journal Article↗

A triboluminescent europium(III) complex.

The crystal structure of (4,4'-dimethyl-2,2'-bipyridyl)tris[3,3,3-trifluoro-1-(2-thenoyl)propan-2-onato]europium(III), or more commonly (4,4'-dimethyl-2,2'-bipyridyl)tris(2-thenoyltrifluoroacetonato)europium(III), [Eu(C8H4F3O2S)3(C12H12N2)], has been determined. Crystals of the complex emit vivid red light when scratched or fractured. This triboluminescent activity seems to correlate with the non-centrosymmetric crystal structure and disorder of the thienyl rings and CF3 groups which is present here and in similar compounds. While modeling the thienyl-ring disorder, it was noted that the bond angle at the C atom replaced by S is a sensitive sign of even small rotational ring disorder. The coordination geometry of the Eu(III) ion can be described as square antiprismatic, with coordination by the six O atoms of the three chelating beta-diketonate ligands and the two N atoms of the neutral bipyridyl ligand.

Journal Article↗