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Natesa Pandian

Publications and source records attributed to Natesa Pandian.

6 recordsLinked to original sources
PubMed2006

Evaluation of peripheral vascular endothelial function with a portable ultrasound device.

Endothelial function can be assessed noninvasively by imaging the brachial artery with ultrasound before and during reactive hyperemia. However, the standard ultrasound equipment typically used for this purpose is limited by size and expense of the machinery. In this study, we compared the ability of a portable ultrasound device to standard ultrasound equipment to visualize the brachial artery for purposes of assessing peripheral vascular endothelial function. The portable device provided comparable imaging of the brachial artery at rest and during hyperemia to that of standard ultrasound technology. These findings support the feasibility of noninvasive evaluation of peripheral endothelial function in the ambulatory setting.

Adult↗
PubMed2006

Distribution of potential cardiac sources of embolism in young and older stroke patients: implications for recurrent vascular events.

BACKGROUND: Transesophageal echocardiography (TEE) has improved the diagnostic evaluation of ischemic stroke patients, permitting detection of potential cardiac sources of embolism. The present study aimed to evaluate the distribution of potential cardioembolic sources in young versus older stroke patients and their clinical implication for recurrent vascular events. Two hundred and twenty-eight patients with undetermined ischemic stroke were enrolled in the study. METHODS: All patients were submitted to transthoracic and to TEE examination. The mean follow-up period was 43 +/- 19 months. RESULTS: The overall detection of cardiac sources of embolism was significantly higher in younger than in older patients (P = 0.006). Atrial septal abnormalities were more prevalent in the younger than in the older population (P = 0.006), whereas complicated aortic plaques were detected more often in older patients. During the follow-up period of 4-5 years, we identified 40 recurrent stroke episodes or vascular deaths. As expected, there was a significant difference in recurrent vascular events and death of older patients compared to the younger ones (P = 0.025). CONCLUSIONS: The present study demonstrates that atrial septal abnormalities and aortic atheromas are the most prevalent echocardiographic findings in young and elderly stroke patients, respectively. Complicated aortic atheroma is strictly correlated with recurrent cerebral vascular events or death.

Adult↗
PubMed2004

Blood cyst of the mitral valve apparatus in a woman with a history of orthotopic liver transplantation.

Blood cysts within the heart are rare findings in adults. We describe a case of a woman with a history of orthotopic liver transplantation who presented for an echocardiogram to evaluate a potential source of cerebrovascular embolism. A cystic mass attached to the submitral valve apparatus was identified by transthoracic and confirmed by transesophageal echocardiography. Surgical exploration and pathologic examination confirmed the mass to be a blood cyst attached to the chordal apparatus of the posterior papillary muscle. This case report highlights the use of echocardiography in diagnosing intracardiac blood cysts.

Blood↗
PubMed2002

Determination of left ventricular mass by three-dimensional echocardiography: in vitro validation of a novel quantification method using multiple equi-angular rotational planes for rapid measurements.

UNLABELLED: Measuring left ventricular mass by m-mode echocardiography or two-dimensional echocardiography is limited by the fact that calculations are based on assumptions, which describe left ventricular shape by simple geometric figures. The ability of three-dimensional echocardiography (3-DE) to accurately assess left ventricular mass has been shown previously, but 3-DE approaches to quantitative analysis of ventricular mass required multiple tomographic sectioning, manual tracing in various cut planes and were time consuming and laborious. We investigated the accuracy of a novel, rapid method of 3-DE mass quantification using multiple rotational planes in left ventricles in vitro. METHODS: Three-dimensional data sets of 10 fixed pig hearts were obtained using a TomTec 3-DE system. For 3-DE mass calculations, a rotational axis in the center of the ventricle (apical-basal orientation) was defined and 3, 6 and 12 equi-angular rotational planes were created. The endocardial and epicardial contour of the left ventricle was traced in each cut plane and the volume of the corresponding myocardial wedge was automatically calculated. Mass was calculated by multiplying the resulting myocardial volume by the specific weight of myocardial tissue. The measurements were performed by two investigators blinded to the anatomic true mass and were analyzed for interobserver and intraobserver variability. RESULTS: The anatomic left ventricular mass was measured 73-219 (168 +/- 50) g. 3-DE mass ranged from 88-247 (207 +/- 51) g (three planes), 84-250 (205 +/- 52) g (six planes) and 86-241 (202 +/- 50) g (12 planes) respectively. The correlation between 3-DE mass and anatomic LV mass measurements (r = 0.92) and between two observers (r = 0.97-0.98) was good. True mass was slightly overestimated by 3-DE measurement (SEE = 22-23 g). The intraobserver and interobserver variabilities were < or = 4 and < or = 7% respectively for all measurements. CONCLUSION: This new 3-DE method of left ventricular mass quantification with rotational approach provides accurate and reproducible measurements. In normal shaped left ventricles even three planes were sufficient to provide accurate mass measurements in vitro.

Animals↗
PubMed1996

Three-Dimensional Echocardiographic Reconstruction of the Left Ventricle by a Transesophageal Tomographic Technique: In Vitro and In Vivo Validation of its Volume Measurement.

Accurate determination of left ventricular (LV) volume has important therapeutic and prognostic implications in patients with cardiac disease. Volume estimations by two-dimensional techniques are not very accurate due to geometric assumptions. OBJECTIVES: To validate LV volume determinations by a new transesophageal three-dimensional echocardiographic technique. We performed three-dimensional reconstruction of the LV using an echo-computed tomographic (CT) technique based on serial pullback parallel slice imaging technique in both in vitro and in vivo settings. Fourteen latex balloons with various sizes (30-235 mL) and shapes (conical, pear shaped, round, elliptical, and aneurysms in various locations) filled with known volumes of water were imaged in a water bath. From the static three-dimensional image, the LV long axis was defined and the LV was sectioned perpendicular to this axis into 2-mm slices. The volume of each slice was calculated with the observer blinded to the actual volume as the product of the slice thickness and the manually traced perimeter of the slice and the LV volume as the sum of the volumes of the slices (Simpson's method). The calculated LV volume closely correlated with the actual volume (r = 0.99, P < 0.0001, calculated volume = 1.06x - 11.3, Deltavolume = -5.7 +/- 10.0 cc). Using the same system, transesophageal echocardiographic (TEE) images of the LV were obtained in 15 patients gated to respiration and ECG. Satisfactory dynamic three-dimensional reconstruction of the LV was possible in ten patients. The three-dimensional LV volumes (systolic and diastolic) using Simpson's method correlated well with those obtained from biplane or multiplane TEE images using the area length method (r = 0.89, p < 0.0001, y = 12.7 + 0.84x, Deltavolume = 1.3 +/- 18.1 cc). The LV major-axis diameters by the two methods showed very close correlations as well (r = 0.86, P < 0.0001, y = 19 + 0.74x, Deltadiameter = 1.0 +/- 7.2 mm). We conclude that three-dimensional LV volume calculation by the echo-CT technique is intrinsically sound, is independent of LV geometry, and with some limitations, is applicable in vivo. (ECHOCARDIOGRAPHY, Volume 13, November 1996)

Journal Article↗