Biomedical subjects

Nedal Hejazi

Publications and source records attributed to Nedal Hejazi.

9 recordsLinked to original sources

PubMed2006

Cavernous malformations of the orbit: a distinct entity? A review of own experiences.

We collected data to provide evidence that orbital cavernous malformations (CMs) are histopathologically, neuroradiologically, and clinically different from cerebral CMs and may represent a distinct entity. In this study, the main clinical, histopathological and radiological characteristics of 19 patients (11 females and eight males, mean age 49.1 years) with orbital CMs out of a series of 376 orbital tumors are analyzed and compared with 107 cases with cerebral CMs treated in the same period. Decrease of visual acuity and painless progressive proptosis were the main clinical signs observed in 17 patients (89%). Complete microsurgical excision of lesions via individualized approaches was obtained in all cases. Follow-up examinations were obtained after a mean of 3.1 years (11 months to 7 years) and yielded complete recovery in 14 patients, while five remained clinically unchanged. Based on clinicopathological and neuroradiological studies of these 19 patients with orbital and 107 patients with cerebral CMs treated in the same period, we found evidence that orbital CMs have specific features to distinguish them from cerebral CMs. Orbital CMs, in contrast to the cerebral CMs, showed non-degenerated well-developed vessel walls and were covered by a hard and compact capsule. Clinical symptoms are characterized by the growth of orbital CMs due to intraluminal thrombosis and subsequent recanalization of cavernous vessels; there were no signs of hemorrhage. We found evidence to suggest that orbital CMs represent a distinct clinicopathologic and neuroradiologic entity.

Adult↗

PubMed2006

Intraorbital lymphomas: neurosurgical experiences and management strategies.

Intraorbital lymphoma is a rare event. The aim of this study was to evaluate the clinical features, management, and outcome of patients with intraorbital lymphoma. The data of twenty-one individuals (12 women, nine men, aged 33 years to 84 years, mean age 62 years) with intraorbital lymphoma diagnosed between 1994 and 2003 were reviewed. Fifteen patients had no signs of systemic lymphoma disease. After the diagnosis of lymphoma had been surgically confirmed, chemotherapy alone was administered to seven patients, only radiotherapy was employed in nine, and both therapies were administered to five patients. With this treatment it was possible to obtain relief of orbital symptoms in 14 patients (67%) for at least 1 year. Three patients remain unchanged in their decreased visual capabilities. Local recurrence was observed in four cases and was treated with chemotherapy. Individualized microsurgical approaches to the orbit and adequate adjuvant therapy (radiotherapy, steroids, and chemotherapy, separate or in combination) are necessary to achieve satisfactory remission of orbital lymphomas.

Adult↗

PubMed2005

Frameless image-guided neuronavigation in orbital surgery: practical applications.

Frameless neuronavigation has been increasingly used in intracranial and spinal neurosurgery. However, the application of neuronavigation in orbital surgery has not yet been reported. The purpose of this study was to evaluate whether frameless navigation in the orbit provides sufficient clinical application accuracy and thus a useful tool in orbital surgery. A frameless infrared-based neuronavigation system (VectorVision, BrainLAB, Heimstetten, Germany) was used in the microsurgical removal of 11 orbital tumors (five cavernomas, three lymphomas, two dermoid tumors, and one rhabdomyosarcoma). The transconjunctival approach was performed in seven cases, lateral orbitotomy in three cases, and the extradural pterional approach was performed in one case. The surgery was successful and without any complications in all cases. The registration accuracy of the neuronavigation was between 1.8 and 2.2 mm, with a mean of 1.9 mm. Subtotal tumor debulking was performed in one case with lymphoma. One patient was only biopsied due to suspected systemic lymphoma disease. Total removal of the tumor could be accomplished in the other nine patients. Image guidance during orbital surgery offered excellent three-dimensional guidance on the surface of the intraorbital lesions, allowing a safer, more controlled surgery. The surgical targets in the orbit are fixed structures, thus no shifting occurs and continuous high intraoperative navigation accuracy can be achieved. The use of the navigation clearly reduces the operative risk and increases the effectiveness of microsurgical orbital procedures.

Adult↗

PubMed2005

Microsurgical infrapedicular paramedian approach for retrovertebral lumbar disc herniations. Technical note.

The author performed a microsurgical infrapedicular paramedian approach in 35 patients (23 men and 12 women) to remove herniated lumbar retrovertebral discs that did not have an apparent origin at either the superior or inferior disc level. The goal of this surgery was to minimize the bone resection, preserve the facet joint, and avoid the risk of secondary vertebral instability. The Macnab outcome classification was used to assess all patients who attended follow-up examination for at least 15 months. The clinical results were excellent or good in 34 (97%) of 35 cases. This minimally invasive lumbar spine technique resulted in minimal morbidity, excellent clinical benefits, and a long-term outcome without evidence of secondary segmental instability.

Adult↗

PubMed2003

Intraoperative cervical epidurography: a simple modality for assessing the adequacy of decompression during anterior cervical procedures. Technical note.

OBJECT: Intraoperative cervical epidurography (ICE) was used during anterior cervical procedures to assess the success of bone resection and indicate the need for immediate correction in the event of inadequate decompression. METHODS: The adequacy of decompression was assessed by the operating neurosurgeon who performed ICE after anterior microdiscectomy with exposure of the dura mater. If the decompression was deemed inadequate, additional bone was removed using a high-speed drill. Epidurography was conducted after each subsequent decompression until adequate bone removal was achieved. This was undertaken in 39 patients undergoing anterior cervical procedures. Nine patients underwent corpectomy, 21 one-level, and nine two-level discectomy. The ICE revealed insufficient resections requiring additional bone removal in 14 (36%) of the 39 patients. CONCLUSIONS: The goal of ICE is to ensure adequate decompression, and if such has not been achieved, to allow for additional immediate bone excision. Furthermore, ICE provides additional real-time control of the position of cages and screws to avoid dural tear or spinal cord compression. Because of this immediate feedback, the success rate of anterior cervical procedures can be improved. The advantages of this modality include real-time assessment, low cost, simplicity, and speed.

Decompression, Surgical↗

PubMed2002

Spinal intramedullary teratoma with exophytic components: report of two cases and review of the literature.

True intramedullary teratoma is an extremely rare tumor, with only seven cases reported in the literature. The authors present two personal cases of spinal intramedullary cystic teratoma of the conus medullaris with exophytic growth and some unusual aspects. Their cases are unusual not only because they were diagnosed by MRI but also because the monitored microsurgical removal of the tumor was apparently total, with excellent results, in clinical and neuroradiologic terms. We recommend early radical surgery whenever possible, when the patient's neurological status is still good. To prevent traumatizing adjacent spinal cord for cases in which the teratoma tightly adheres to the functional neurological tissue of the spinal cord with no cleavage plane, we do not recommend an aggressive surgical attempt. Because of the mostly benign nature of this disease, the symptomatic recurrence of such incompletely resected mature teratomas is slow and may eventually require a second surgical procedure. The relevant literature is also reviewed.

Adult↗

PubMed2002

Unilateral decompressive craniectomy for children with severe brain injury. Report of seven cases and review of the relevant literature.

UNLABELLED: Severe head injuries in children (under 15 years of age) have many features that differentiate them from head injuries in adults. In such cases, non-surgical treatment cannot always prevent fatal herniation. We report on seven cases of children with severe head injury, presenting with decorticate posturing and treated by unilateral decompressive craniectomy. The aim of the unilateral decompressive craniectomy was to decompress the midbrain and the brainstem. Post-operatively, all patients showed good recovery within 5 weeks (Glasgow Coma Scale score 15). The alternative treatment modalities are discussed critically in an attempt to determine the value of the unilateral decompressive craniectomy procedure and to define the clinical parameters that might identify those children most likely to benefit from this technique. CONCLUSION: the unilateral decompressive craniectomy has an advantage over non-surgical treatment of children with severe brain injury and should be considered in their management.

Adolescent↗

PubMed2002

Bilateral subdural effusion and cerebral displacement associated with spontaneous intracranial hypotension: diagnostic and management strategies. Report of two cases.

The authors describe two patients with bilateral subdural effusion and cerebral displacement associated with spontaneous intracranial hypotension (SIH) and discuss the possible pathophysiological origins of these abnormalities. The signs seen on magnetic resonance imaging in both cases, such as tonsillar descent, subdural effusion, meningeal enhancement, downward displacement of the optic chiasm, and crowding of this structure and the hypothalamus between the pituitary gland and brain, can help to establish the diagnosis of SIH. Therapy with a lumbar epidural blood patch resulted in the rapid resolution of all symptoms and most morphological abnormalities. The authors propose diagnostic and management strategies based on their own experiences and the reported cases of SIH in the medical literature.

Algorithms↗

PubMed2002

Combined transarticular lateral and medial approach with partial facetectomy for lumbar foraminal stenosis. Technical note.

The authors performed a microsurgical combined transarticular lateral and medial procedure with partial facetectomy in 24 patients (16 men and nine women) with lumbar intervertebral foraminal stenosis to decompress the affected nerve root. The goal of this surgery was to maintain the integrity of the facet joint, to guarantee satisfactory exploration, and to obtain a sufficient decompression of the intervertebral foramen. Because only minimal bone resection is required, the risk of secondary instability induced by complete facetectomy is avoided. The clinical results of this procedure were excellent in the majority of cases. The mean follow-up period was 21.8 months.

Adult↗