Biomedical subjects

Neeraj Awasthy

Publications and source records attributed to Neeraj Awasthy.

4 recordsLinked to original sources

PubMed2005

Brain abscesses with pemphigus vulgaris: a rare association.

Pemphigus is a rare group of skin disorders characterized by blistering because of loosening of desmosomal links between epidermal cells attributed to immunological attack. Pemphigus vulgaris is characterized by the presence of the split within the epidermis just above the basal layers (suprabasal). Central nervous system complications of the disorder have scantily been described in the English literature. We report what we believe to be the first case of cerebral abscesses in a 38-year-old male associated with pemphigus vulgaris and immunosuppressive therapy.

Adult↗

PubMed2005

Primary hydatid disease of the spine: an unusual case.

Hydatid disease or hydatidosis caused by Echinococcus granulosus is the most widespread, serious human cestode infection in the world. Bone involvement is reported in 0.5-4% with spinal involvement reported in 50% of these cases. We report a case of this rare entity of an isolated primary hydatid cyst of the spine in a 15-year-old boy, who presented with progressive back pain for 8 months, lower extremity weakness and urinary incontinence for 3 months. Neurological examination was suggestive of upper motor neuron type of paraperesis grade 1/5 with complete sensory loss below T4 level. MRI of the spine showed multiple cystic extradural lesions at the T4-5 level with involvement of the paraspinal muscles. The patient underwent a T4-5 laminectomy, and a total excision of the multiple epidural and paraspinal cysts. The diagnosis of hydatid disease was confirmed on histopathology. Albendazole was started postoperatively. At 6 months follow-up the boy had no neurological deficit, was playful, active and walking. Postoperative MRI at 6 months showed no recurrence of the lesion. Analysis of the other reported cases is discussed with relevance to our case.

Adolescent↗

PubMed2004

Congenital hypofibrinogenemia.

Congenital afibrinogenemia/hypofibrinogenemia is an extremely rare coagulation disorder. We describe a case of congenital hypofibrinogenemia in a 6-year female child, who presented with recurrent ecchymotic spots with no frank bleeding.

Afibrinogenemia↗

PubMed2004

Neonatal lupus erythematosus.

We describe case report of a 45 days old male baby with neonatal lupus erythematosus, who presented with 3rd degree congenital heart block and depigmented skin lesions on face and upper part of body. Diagnosis of the baby was confirmed by anti nuclear levels and skin biopsy.

Antibodies, Antinuclear↗