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Biomedical subjects

Newton Kara-José

Publications and source records attributed to Newton Kara-José.

16 recordsLinked to original sources

Pediatric and adolescent population with visual impairment: study of 385 cases.

OBJECTIVE: To analyze data on the pediatric population attending the Ophthalmologic Clinic's Low Vision Service at the São Paulo University Medical School. METHODS: Low vision ophthalmologic assessment, from April 1998 to December 2003, of 385 children and adolescents with mean age of 7 years; 51.7% males and 48.3% females. The main data analyzed were age, diagnosis, anatomic site of the ocular injury, visual acuity, and prescription of optical aids. RESULTS: 45.4% were below 6 years, and 54.6% were between 6 and 16 years. 35.5% experienced moderate visual impairment, 26% had severe visual impairment, 8.6% had profound visual impairment, 10.6% were near blind, and 1.6% were blind. The main causes of visual impairment included congenital glaucoma (30.6%), macular retinochoroiditis due to congenital toxoplasmosis (16.7%), congenital cataract (12.8%), retinal and macular inherited disorders (11.7%), and optic atrophy (9.8%). Among school-age children, 52.9% received a prescription of optical aids. The most widely used optical aids for distance were 2.8 X 26 (34.4%); 4.2 X 12 (30.3%); and 6 X 17 (26.8%) telescopic systems. The most frequently prescribed optical aid for near vision was the 2x magnifying bar (33.3%). CONCLUSIONS: There is a need for prevention of primary (congenital infections), secondary (congenital glaucoma and retinopathy of prematurity), and tertiary (congenital cataract) visual impairment. The prescription of optical aids for school-age children will help them perform better at school and contribute to their social inclusion.

Adolescent↗

[Utilization of optical devices and equipments by students with visual impairment].

PURPOSE: To verify perceptions and conduct of students with visual impairment regarding devices and equipment utilized in schooling process. METHODS: A transversal descriptive study on a population of 12-year-old or older students in schooling process, affected by congenital or acquired visual impairment, inserted in the government teaching system of Campinas during the year 2000. An interview quiz, created based on an exploratory study was applied. RESULTS: A group of 26 students, 46% of them with low vision and 53.8% affected by blindness was obtained. Most of the students were from fundamental teaching courses (65.4%), studying in schools with classrooms provided with devices (73.1%). Among the resources used in reading and writing activities, 94.1% of the students reported they used the Braille system and 81.8% reported that the reading subject was dictated by a colleague. Most of the students with low vision wore glasses (91.7%), and 33.3% utilized a magnifying glass as optical devices. Among the non-optical devices, the most common were the environmental ones, getting closer to the blackboard (75.0%) and to the window (66.7%) for better lighting. CONCLUSIONS: It became evident that students with low vision eye-sight made use of devices meant for bearers of blindness, such as applying the Braille system. A reduced number of low vision students making use of optical and non-optical devices applicable to their problems were observed, indicating a probable unawareness of their visual potential and the appropriate devices to improve efficiency.

Child↗

Problem-solving capacity for vitreoretinal diseases in a university health center.

PURPOSE: To evaluate the effectiveness of the tertiary care delivered to patients with vitreoretinal diseases in a defined urban population; to substantiate the planning and allocation of resources in order to improve the tertiary eye care delivery system in a specific area. METHODS: Data were collected from consecutive first-time patients between June 1, 2003 and July 31, 2004 in the Department of Ophthalmology, State University of Campinas, São Paulo, Brazil. Problem-solving capacity values were calculated for vitreoretinal surgery and photocoagulation. Data were entered into the Statistical Package for the Social Sciences (version 10.0). RESULTS: Of the 7500 patients referred to the Department, 641 were deemed suitable for analysis. The diagnoses analyzed were retinal detachment (26.0%), diabetic retinopathy (21.0%), and vitreous hemorrhage (7.7%). The median ages were 52, 59 and 57.5, respectively. Of all patients referred for retinal detachment, 26.5% were inoperable. The values obtained for the problem-solving capacity (PSC) showed that 38.1%, 33.0% and 93.5% of those eligible for an ophthalmic intervention (for retinal detachment, vitreous hemorrhage and diabetic retinopathy) had obtained treatment. The main reason for not giving treatment was the unavailability of operating room time and photocoagulation time (87.1%). CONCLUSIONS: This was the first study of tertiary eye care service performance in Latin America. Sight-threatening conditions such as retinal detachment and diabetic retinopathy are not thoroughly covered by the health system in this area. Various ways to reduce the problem are considered. The study has provided valuable information on planning high-complexity eye services in the population in question.

Academic Medical Centers↗

Second eye cataract surgery: perceptions of a population assisted at a university hospital.

OBJECTIVE: To identify daily life difficulties perceived by patients suffering from senile cataract before and after second eye cataract surgery. METHODS: Longitudinal prospective study with 84 patients consecutively seen within the framework of the Cataract Project, with visual acuity equal to or higher than 20/30 in the pseudophakic eye, and equal to or lower than 20/40 with the best possible optical correction in the cataractous eye. A questionnaire was applied during an interview. RESULTS: Before surgery, 60.7% complained about visual impairment (moderate or marked); after surgery, 92.8% had no difficulty. Routine activities, mobility, and leisure activities were significantly altered after surgery (P =.001). CONCLUSION: According to the patients' perceptions, there was a significant reduction in visual difficulties after second eye cataract surgery.

Activities of Daily Living↗

[Treatment of diabetic retinopathy: patients' perceptions in Rio Claro (São Paulo State)--Brazil].

PURPOSE: To collect information and opinions from a group of diabetic patients regarding diabetic retinopathy and its treatment, in order to get reliable information that can help to improve programs and actions to control and prevent this ocular disease. METHODS: A cross-sectional study was performed. The sample was from 980 diabetic patients seen in a diabetic association. A previous questionnaire was made with general questions about the main subject. Thereafter, an appropriate questionnaire was prepared. RESULTS: The sample showed that among 299 patients with age ranging from 16 to 83 years, with a mean of 57 years, mainly female (67.91%) did not know how severe their disease was (30.8%), or believed that it was not a serious problem (19.7%). The laser technique to solve diabetic retinopathy was known by 60.2% of the patients. It was reported as the only treatment available by 24.1%. Among the reasons for no treatment 59.8% reported that they did not think it was necessary and 29.7% could not afford it. CONCLUSIONS: Patients showed lack of knowledge about how serious is diabetic retinopathy, the possibility of using laser technique for it and the severity of the disease. Some patients believed in the efficacy of the treatment and some patients did not, but all of them reported that they were afraid of submitting to it.

Adolescent↗

[Predictive value of preoperative fasting glucose test of diabetic patients regarding surgical outcome in cataract surgery].

OBJECTIVE: To determinate the predictive value of preoperative glucose test of diabetic patients, with age above 40 years, for visual acuity outcome and clinical perioperative complications, in cataract surgery with local anesthesia, in an academical medical center. METHODS: Type 2 diabetic patients, above 40 years of age, indicated for cataract surgery between February 10, 2000 and January 10, 2001, at the State University of Campinas, São Paulo, Brazil. All patients had a preoperative medical assessment by a physician one week before surgery, and were submitted to serum fasting glucose test and 12-lead electrocardiogram. There was no delay in the surgeries of patients with abnormal serum glucose test results, so, the result of the test alone was not a reason to cancel the surgery. According to the glucose test, the patients were assigned to one of two groups: Normal Glucose Test Group (60-115 mg/dL) or Abnormal Glucose Test Group (>115 mg/dL). Postoperative best-corrected visual acuity and clinical perioperative complications were recorded on a standardized form. RESULTS: The sample consisted of 193 patients. 67 (34.7%) had a serum glucose test within normal limits (normal glucose test group) and 126 (65.3%) outside normal limits (abnormal glucose test group). The mean result of the "normal glucose test group" was 98.5+/-17.3 mg/dL and 166.5+/-48.9 mg/dL for the "abnormal glucose test group" (p<0.001). We observed perioperative complications in 21 (10.7%) patients, all arterial hypertension cases; 7 (10.5%) of these in patients with normal glucose test result and 14 (11.1%) in patients with abnormal result (p<0.888). The postoperative best-corrected visual acuity was similar in both groups. CONCLUSION: There was no influence of the preoperative serum glucose level on perioperative clinical complications or visual acuity outcome.

Adult↗

[Waste of medical tests in preoperative evaluation for cataract surgery].

The objective of this clinical trial was to determine the frequency of medical tests considered unnecessary in routine preoperative evaluation for cataract surgery. Unnecessary costs with these tests were also evaluated. For patients assigned to the selective testing group, it was requested that no preoperative testing be performed unless the patient presented a new or worsening medical problem warranting medical evaluation with testing. For patients assigned to the routine testing group, three tests were requested: a 12-lead electrocardiogram, complete blood count, and serum glucose level. The costs of tests considered unnecessary were calculated. The sample of 1,025 patients consisted of 512 assigned to the routine testing group and 513 to the selective testing group. Cumulative rate of medical events was similar in the two groups (p=0.923). The selective group underwent 60.7% fewer tests. The results suggest that selective preoperative testing in cataract surgery does not harm patients in terms of peri-operative clinical complications and also represents a significant cost reduction compared to routine testing.

Adult↗

Are routine preoperative medical tests needed with cataract surgery? Study of visual acuity outcome.

PURPOSE: The aim of this prospective randomized clinical trial was to investigate whether routine medical testing before cataract surgery reduced the rate of ocular surgical complications and to study its impact on visual acuity outcome. METHODS: The study was carried out in an academic medical center in Brazil, at State University of Campinas, between 10 February 2000 and 10 January 2001. The scheduled cataract operations were randomly assigned to one of two groups: 1) to be preceded by routine medical testing (the "routine-testing group") or 2) not to be preceded by routine medical testing (the "selective-testing group"). If the patient was assigned to the selective-testing group, it was requested that no preoperative testing be performed unless the patient presented with a new or worsening medical problem that would warrant medical evaluation with testing. In the case of patients assigned to the routine-testing group, three tests were requested: a 12-lead electrocardiogram, a complete blood count, and measurements of serum glucose. Ocular surgical complications, preoperative and postoperative best-corrected visual acuity were recorded on a standardized form. RESULTS: The sample of 1025 patients scheduled to undergo cataract surgery was comprised of 512 assigned to the routine-testing group and of 513 assigned to the selective-testing group. The two groups had similar proportions of operations canceled and not subsequently rescheduled, 2% in each group. The cumulative rate of ocular surgical complications was similar in the two groups, 20.5% in the routine-testing group and 19.3% in the selective-testing group (p = 0.624). The preoperative and the postoperative best-corrected visual acuity were similar in both groups (p = 0.999 in the former and p = 0.664 in the latter). CONCLUSIONS: The results of this study suggest that routine medical testing before cataract surgery did not reduce the rate of ocular surgical complications and did not influence visual acuity outcome.

Academic Medical Centers↗

[Predictive value of preoperative tests in facectomy].

OBJECTIVE: To establish the prevalence of abnormal results in routine preoperative tests prior to facectomies and whether they influence the occurrence of perioperative clinical complications. METHODS: This prospective study was developed in an academic medical center in Brazil. Besides a clinical evaluation, all patients were requested to undergo an electrocardiogram, complete blood work and fasting blood glucose test. Patients younger than 40 years of age who had had previous eye surgery, candidates for general anesthesia or who had suffered acute myocardial infarction up to three months before surgery were excluded from the study. Intraoperative medical events were recorded in a protocol form. Analysis was carried out using Fisher's test and ANOVA (analysis of variance). RESULTS: The sample was composed of 746 patients, 405 (54.3%) were men. The average age was 66.6+/-11.6 years. Intraoperative complications occurred in 71 (9.5%) patients. There were abnormal results in 13.5% (101 patients) of hemoglobin dosages and in 16.6% (124) of fasting blood glucose. As for electrocardiograms, abnormalities were found in 46.6% (348) of the subjects. There was a higher prevalence of electrocardiograms with abnormal values in patients who had perioperative clinical complications (p=0.02). There were no statistically significant differences between hemoglobin dosages (14.0+/-1.6 g/dL in patients without intraoperative complications and 14.3+/-1.3 g/dL in patients with complications - p=0.150) and fasting blood glucose (104+/-29 mg/dL in patients without complications and 105+/-41 mg/dL in patients with complications - p=0.850). CONCLUSIONS: Within the investigated routine of preoperative testing for facectomy, only the abnormal electrocardiogram results influenced the occurrence of complications in the perioperative period.

Aged↗

Self-evaluation of contact lens wearing and care by college students and health care workers.

PURPOSE: To identify perceptions related to the wear and care and of contact lenses and self-evaluation of the knowledge regarding their cleaning and disinfection. METHODS: A survey was conducted by interviewing contact lens wearers among health care workers at a university hospital. RESULTS: Two hundred one contact lens wearers were interviewed. The average age was 23.5 years; 69.2% were female and 71.1% were college students. Approximately 55% did not consider themselves good wearers and declared as the main reason the inadequate maintenance of the contact lenses and their cases. Regarding contact lens care, 79.1% of respondents admitted not performing it correctly. CONCLUSION: Although the interviewees were health care workers, their self-evaluation regarding contact lens care showed unsatisfactory knowledge and practices related to the use and care of contact lenses.

Adolescent↗

Full-threshold versus Swedish Interactive Threshold Algorithm (SITA) in normal individuals undergoing automated perimetry for the first time.

PURPOSE: To compare the full-threshold (FT) and Swedish Interactive Threshold Algorithm standard (SS) strategies in normal individuals undergoing automated perimetry for the first time. DESIGN: Randomized, comparative, observational case series. PARTICIPANTS: Eighty perimetrically naive normal individuals. METHODS: All individuals underwent computerized visual field examinations (30-2, Humphrey 750, Humphrey-Zeiss, Dublin, CA) with both FT and SS strategies. One eye of each individual was tested. Test order between strategies was randomized. MAIN OUTCOME MEASURES: The following variables were compared: test time, foveal threshold, fixation losses, false-positive and false-negative errors, mean deviation, pattern standard deviation, glaucoma hemifield test, and number of depressed points deviating at P < 5%, P < 2%, P < 1%, and P < 0.5% on the total and pattern deviation probability maps. Initially, we compared the results of all FT and SS tests, regardless of the order in which they were applied. Next, patients undergoing SS as the first examination were compared with those undergoing FT as the first test. Finally, the SS and FT results obtained in the second test were compared. Anderson's criteria were applied to define abnormal examinations, allowing for the calculation of the specificity of the SS and FT strategies. RESULTS: When the results of all FT and SS tests were analyzed, the number of significantly depressed points deviating at P < 5%, P < 2%, and P < 1% on the pattern deviation probability maps was higher with the SS strategy (P < 0.05); the specificity was 50% for SS and 72.5% for FT (P < 0.01). When only first examinations were compared, the number of significantly depressed points deviating at P < 5%, P < 2%, and P < 1% on both the total and pattern deviation probability maps was higher with the SS strategy (P < 0.05); the specificity was 38.1% and 63.2% for the SS and FT strategies, respectively (P = 0.04). When only the second examinations were compared, there were no significant differences either between the number of depressed points or between the specificities of both strategies (73.7% for SS and 71.4% for FT) (P = 0.98). CONCLUSIONS: Normal individuals with no perimetric experience may present more significantly depressed points on the pattern deviation probability map when the SS strategy is used, reducing the test specificity in comparison with FT. These findings are probably due to a lower interindividual variability observed with SS. However, these differences disappeared in a second examination, suggesting that both strategies perform similarly in perimetrically experienced individuals.

Adolescent↗

Long-term visual outcomes in the Cataract-Free Zone Project in Brazil.

PURPOSE: To determine the long-term visual outcomes and causes of poor vision in the cataract population in Brazil treated in the Cataract-Free Zone Project. METHODS: Project A subjects (62 patients) were recruited in Taquaritinga, SP, 26 months after surgery. Project B subjects (34 patients) were recruited in São João da Boa Vista, SP, 43 months after surgery. All patients underwent visual screening and eye examination (examination 1). They were classified according to visual acuity in the operated eye and the causes of poor vision were diagnosed and referred for treatment. The results of these interventions were collected (examination 2) and analysed by Chi-square test. RESULTS: At examination 1 in project A, 47 of 62 patients (75.6%) had visual acuity < or = 20/100. The main causes of poor vision were refractive error (31.9%) and posterior capsule opacification (17.0%), with or without refractive error. At examination 1 in project B, 22 of 34 patients (64.7%) had visual acuity < or = 20/100. The main causes of poor vision were again posterior capsule opacification (50.0%) and refractive error (9.0%). After posterior capsulotomy with Nd:YAG laser and prescription of new corrective eyeglasses, visual acuity = 20/80 was obtained in 64.5% of patients in project A (OR = 0.18, CI = 0.07-0.41) and 70.5% of patients in project B (OR = 0.19, CI = 0.06-0.60) at examination 2. The causes of blindness in the remaining patients were identified. CONCLUSION: This type of project is effective in reducing blindness caused by cataracts in developing countries. However, long-term scheduled follow-up of operated patients is an effective means of avoiding consecutive blindness resulting from secondary cataracts and refractive changes.

Aged↗

Prognostic factors in open globe injuries.

PURPOSES: To evaluate the main factors related to visual outcome after open globe injuries (excluding intraocular foreign bodies). METHODS: Retrospective study analyzing consecutive ocular lacerations, primarily repaired in this institution, between January 1993 and January 2000. Of the 364 cases, 283 (77.75%) lacerations were statistically analyzed, correlating the preoperative variables with the postoperative visual acuity (VA). Excluded from this study were all patients with less than 6 months of follow-up, previous ocular surgery, unreliable information on VA, intraocular foreign bodies and endophthalmitis. When a bilateral injury was detected, only 1 eye was randomly chosen. RESULTS: It was observed, after statistical analysis (multivariate analysis), that the most important factors related to postoperative poor VA (less than 20/100) were: the length of the laceration, the elapsed time between the injury and the surgery and the presence or absence of vitreous loss, cataract (lens damage), hyphema, laceration posterior to rectus muscle insertion and retinal detachment. CONCLUSION: With this study, it was possible to point out the most important factors related to visual prognosis in open globe injuries. The results found are similar to results previously reported.

Adolescent↗

Retinal thickness assessed by optical coherence tomography (OCT) in pseudophakic macular edema.

PURPOSE: To evaluate the usefulness of the optical coherence tomography (OCT) retinal map in angiographic pseudophakic macular edema (ACME). METHODS: This is a prospective analysis of a group of 36 pseudophakic eyes at the fifth postoperative week, submitted to optical coherence tomography 2 macular map and fluorescein angiography on the same day and, a control group of twenty-two 20/20 vision eyes with a minimum 6-month postoperative period, submitted to optical coherence tomography 2 macular map only. Exclusion criteria were diabetes, any macular pathology and unreadable optical coherence tomography or angiogram. The angiograms were divided into three groups according to the edema intensity: Group I: level 0 (absence of angiographic pseudophakic macular edema); group II: levels 1 and 2 (incomplete and complete perifoveal angiographic pseudophakic macular edema respectively) and group III: levels 3 and 4 (up to one disc diameter and greater than one disc diameter angiographic pseudophakic macular edema area respectively). The nine zones of the optical coherence tomography macular map were compared between the control and the three subgroups of the study group and, between group I and groups II and III. RESULTS: Among the 36 eyes, 23 (64%) were classified as group I, 10 (28%) as group II and three (8%) as group III. The mean thickness of the fovea zone was 185+/-15 microm for the control group, 189+/-24 microm for group I, 213+/-33 microm for group II and 455+/-38 microm for group III. Significant differences: between group III and the control or group I for all zones (p<0.01) and, between group II and control or group I for the fovea and temporal inner zones (p<0.05). CONCLUSION: The optical coherence tomography retinal map is useful in angiographic pseudophakic macular edema diagnosis.

Adult↗

[Perceptions of ophthalmologists regarding teaching models applied to contact lenses].

PURPOSE: To identify perceptions regarding teaching models applied to contact lenses. METHODS: A transversal study in a readily accessible sample consisting of ophthalmologists (n=39) was performed by applying a questionnaire. RESULTS: The sample consisted of 39 ophthalmologists, 51.3% males and 48.7% females. Regarding frequency prior to courses on contact lenses, 28.2% reported only one course; 25.6% two courses; 5.1% three courses; 2.6% five courses and 2.6% more than 10 courses. 23.1% never attended contact lens courses and 12.8% did not answer the questionnaire. On comparison of previous knowledge with that acquired by the offered course, 59.0% declared that they increased their knowledge a lot; 33.3% reported median increase; 2.6% little increase and 5.1% did not answer. As concerns training in contact lenses, 66.7% answered that they never had any training; 30.7% answered affirmatively and 2.6% did not answer. Among those who had training, 75% declared it was good; 16.7%, very good and 8.3%, regular. CONCLUSION: The offered teaching model for contact lenses was considered very valuable, increasing a great deal of knowledge in most subjects.

Contact Lenses↗

Quality of health care: patient satisfaction in a university hospital.

OBJECTIVE: To evaluate patient characteristics and satisfaction in an outpatient service at a university hospital, aiming at obtaining subsidies for standardization of a quality assessment program. METHOD: Patient-representative sample was selected. It consisted of users of the Ophthalmology Outpatient Service at the Hospital das Clínicas, Universidade Estadual de Campinas (UNICAMP). A structured questionnaire was applied through interview, including the following variables: personal characteristics (gender, age, literacy, job), type of appointment (new patient, follow-up), waiting time for the first appointment, opinion regarding ease of access to the hospital, assistance at the front desk, time spent in the waiting room on the appointed day, quality of care, degree of satisfaction with the consultation and general evaluation of the assistance. RESULTS: The sample was characterized by patients with low literacy and socioeconomic level; 21.7% had a steady income. The majority of them think that it is easy to obtain an appointment. According to patients, the mean waiting time for the appointment was 94.6 minutes and 45.3% of them received no orientation after the appointment. Final evaluation of the quality of assistance was positive and patients were satisfied with the provided assistance. CONCLUSION: Although a high level of satisfaction regarding the provided service was observed, when the various factors that can affect patient satisfaction are considered, users reported limitations as concerns quality. Evaluation allowed a better knowledge about the provided service in a university hospital and pointed to the possibility of implantation of quality assessment routines.

Adolescent↗