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Biomedical subjects

Nicola Rosa

Publications and source records attributed to Nicola Rosa.

At least 19 recordsLinked to original sources
PubMed2006

Anterior chamber depth measurement before and after photorefractive keratectomy: comparison between IOL master and Orbscan II.

PURPOSE: To measure the anterior chamber depth (ACD) with 2 different devices before and after photorefractive keratectomy (PRK). DESIGN: Noncomparative case series. PARTICIPANTS: One hundred forty-three eyes of 143 patients who had undergone PRK with refractive errors ranging from -13.13 diopters (D) to +7 D (mean, -3.67+/-3.58) were analyzed. METHODS: The ACD values preoperatively and at 1, 3, and 6 months postoperatively were measured with the Orbscan II and IOL Master. The results were analyzed using the Pearson correlation. MAIN OUTCOME MEASURE: Anterior chamber depth. RESULTS: The instruments showed good agreement between the measurements before and after surgery. A significant decrease between the preoperative and 1-month postoperative measurements was found in the ACD measured from the epithelium with Orbscan II (P<0.01) and IOL Master (P<0.01). A nonsignificant decrease with both IOL Master (P>0.01) and Orbscan II (P>0.01) was found between 3 and 6 months after surgery. The ACD measured from the endothelium using the Orbscan II showed a significant difference only between the 3- and 6-month follow-up data (P<0.01). CONCLUSIONS: The 2 devices showed good agreement, and the changes detected postoperatively seem to be related not only to corneal thinning but also to anterior segment remodeling.

Adolescent↗
PubMed2005

Reliability of a new correcting factor in calculating intraocular lens power after refractive corneal surgery.

PURPOSE: To test the reliability of a corneal radius correcting factor (R factor) in calculating intraocular lens (IOL) power in eyes that developed cataract after refractive surgery and compare it with the clinical history (CHM) and double-K (DKM) methods. SETTING: Department of Ophthalmology, Second University of Naples, Naples, Italy. METHODS: Nineteen eyes from the literature that underwent cataract extraction and IOL implantation after refractive surgery were used to compare actual postoperative and expected refractive errors utilizing the R factor, CHM, and DKM. Intraocular lens powers were calculated with 3 formulas: SRK/T, Hoffer Q and Holladay 1. The differences were evaluated with the Wilcoxon test and Spearman correlation. RESULTS: With the R factor SRK/T and Holladay 1 formulas gave the best results; 16 (84.2%) and 17 (89.5%) eyes were within +/-2 diopters (D) of emmetropia. With CHM, the best results were obtained using the SRK/T and Holladay 1 formulas; with both formulas 12 (63.2%) eyes were within +/-2 D of emmetropia. With DKM, the best results were obtained using SRK/T and Holladay 1 formulas; with both formulas 10 eyes (52.63%) were in the range of +/-2 D from emmetropia. CONCLUSIONS: The R factor can be used with the SRK/T or Holladay 1 formula because this method seems comparable or superior to DKM and CHM.

Cataract Extraction↗
PubMed2004

Reliability of the IOLMaster in measuring corneal power changes after photorefractive keratectomy.

PURPOSE: To test the accuracy of the IOLMaster (Carl Zeiss) in detecting corneal power changes after photorefractive keratectomy (PRK). SETTING: Department of Ophthalmology, 2nd University of Naples, Naples, Italy. METHODS: Two hundred twenty-five consecutive eyes that had PRK (mean -5.13 diopters [D] +/- 2.98 [SD] [range +0.25 to -16.25 D]) were analyzed. The data included preoperative and postoperative (1, 3, and 6 months) subjective refraction and computerized keratometry. Statistical analysis was performed to determine the correlation between the changes in the subjective refraction at the corneal plane and the changes in keratometry. RESULTS: The mean difference between the changes in refraction and the measured corneal changes was 0.75 +/- 1.13 D (range -3.84 to +7.68 D) at 1 month, 0.92 +/- 1.10 D (range -0.87 to +7.93 D) at 3 months, and 0.75 +/- 0.98 D (range -1.70 to +3.85 D) at 6 months. The difference was significant (P<.001). CONCLUSION: Automated keratometry provided by the IOLMaster did not accurately reflect the effective refractive changes after PRK, particularly in eyes that had a high dioptric treatment.

Adult↗
PubMed2003

Mesalazine-associated benign intracranial hypertension in a patient with ulcerative colitis.

PURPOSE: To report a case of benign intracranial hypertension related to mesalazine use. DESIGN: Observational case report. METHODS: A 23-year-old-woman with sudden visual loss, headache, and a history of ulcerative colitis treated with mesalazine underwent ophthalmologic examination, echography, magnetic resonance imaging, and lumbar puncture. RESULTS: The examinations disclosed benign intracranial hypertension that resolved when mesalazine was discontinued and recurred when the drug was restarted. CONCLUSIONS: We recommend periodic ocular fundus examination for patients undergoing long-term therapy with mesalazine, especially if decreased vision, headaches, or neck stiffness are present, to avoid potentially severe complications of intracranial hypertension

Adult↗
PubMed2002

Expulsive hemorrhage before phacoemulsification.

A 65-year-old white man who was scheduled for cataract extraction experienced a sudden increase in intraocular pressure (IOP) with flattening of the anterior chamber immediately after the anterior capsule incision. The eye was sutured, and because no decrease in pressure was noted, surgery was postponed. The presence of the cataract prevented ophthalmoscopic examination. Echographic examination revealed a hemorrhagic choroidal detachment with involvement of the ciliary body. The patient was examined regularly until the choroidal detachment disappeared 4 weeks later. He then had uneventful phacoemulsification and intraocular lens implantation.

Aged↗
PubMedDate not supplied

Phototherapeutic keratectomy for relief of pain in patients with pseudophakic corneal edema.

PURPOSE: To evaluate the therapeutic effects of phototherapeutic keratectomy in patients with pseudophakic corneal edema METHODS: Phototherapeutic keratectomy was performed in 12 eyes of 12 patients with pseudophakic corneal edema who were awaiting penetrating keratoplasty. All patients underwent planned corneal ablation of 120 microm. Examinations before and after surgery included uncorrected and corrected visual acuity, slit-lamp biomicroscopy, photography, and ultrasonic pachymetry. METHODS: A reduction in pain and a slight increase in visual acuity as well as a decrease in corneal thickness were found over an average 18-month follow-up period (range, 6 to 60 months). CONCLUSIONS: Phototherapeutic keratectomy reduced bullae formation, improved visual acuity slightly, and could be considered a valuable alternative to penetrating keratoplasty if surgery needs to be delayed or is contraindicated.

Aged↗
PubMedDate not supplied

Correlation between automated and subjective refraction before and after photorefractive keratectomy.

PURPOSE: To ascertain whether autorefractometry after photorefractive keratectomy (PRK) provides results that are comparable with subjective refractometry. METHODS: The refractions of 159 eyes before and 1 month after PRK were determined with both automated and subjective refractometry, and the results of the two methods were compared. RESULTS: Before PRK, subjective spherical equivalent refraction ranged from -15.25 to +0.25 D (mean -5.30 +/- 2.64 D) and automated spherical equivalent refraction ranged from -16.13 to -0.50 D (mean -6.10 +/- 2.74 D), with good correlation (r2 = 0.965) between the two methods. One month after PRK, subjective spherical equivalent refraction ranged from -1.63 to +3.50 D (mean +0.98 +/- 0.78 D) and automated spherical equivalent refraction ranged from -2.50 to +3.00 D (mean +0.36 +/- 0.96 D) with poor correlation (r2 = 0.401). CONCLUSION: Autorefractometry is less reliable in eyes after PRK, and consequently software changes are recommended for overcoming this problem.

Adult↗
PubMedDate not supplied

Anterior corneal surface after Nidek EC-5000 multipass and multizone photorefractive keratectomy for myopia.

PURPOSE: To evaluate the correlation between the presence of irregularities in corneal ablation and the number of ablation zones with multipass and multizone photorefractive keratectomy (PRK). METHODS: The differential maps obtained from corneal topography performed before and 1 month after PRK in 62 eyes that had undergone PRK with the Nidek EC-5000 excimer laser were assessed for irregularities. PRK treatment ranged from -1.00 to -16.00 D (mean -5.25 +/- 2.72 D), and the number of zones ranged from one to five. RESULTS: Of 62 differential maps, 27 had an irregular pattern according to the Hersh classification, with a non-significant correlation with the number of treatment zones (chi2 = 5.09, P >.1). CONCLUSION: Our results suggest that corneal topography irregularities arising from multizone PRK were not related to the amount of treatment or to the number of ablation zones.

Adult↗
PubMedDate not supplied

A new method of calculating intraocular lens power after photorefractive keratectomy.

PURPOSE: To find a method of calculating intraocular lens (IOL) power that may be independent of preoperative data, in eyes that have developed a cataract after refractive surgery. METHODS: Prior to and 1 month after PRK, the SRK/T formula was used to calculate IOL power in 88 eyes of 65 patients with a preoperative spherical equivalent refraction between -16.25 to +0.25 D (mean -5.39 +/- 3.19 D). IOL power was calculated by utilizing the spherical equivalent refraction as target both before and after PRK. Utilizing the postoperative corneal radius measurement (R2), an underestimation of the IOL power was found. For this reason, the mean postoperative corneal radius (R3) that gave the same IOL power found before surgery was calculated for each patient. The R3/R2 ratios were plotted against the axial eye length and a linear regression formula was used to calculate R2 correcting factors that gave the new corneal radius (R4). Patients were divided into classes according to axial eye length, and the mean R3/R2 ratios for each class were calculated and used to recalculate the new mean radius (R5). IOL power for emmetropia was calculated in all patients by utilization of R3, R4, R5, the historical method, and the "true corneal power" method. RESULTS: Within +/-0.50 D from the IOL power calculated with R3, R4 gave 35 (39.3%) IOLs, while R5 gave 40 (45.5%) IOLs; the clinical history method gave 24 (27.3%) IOLs and "true corneal power" gave 23 (26.1%) IOLs, with a statistically significant difference P<.001). CONCLUSIONS: Our theoretical method, based on correlation between axial eye length and corneal radius correcting factors, may represent an effective method of calculating IOL power after PRK, especially if the history of the patient is unknown.

Adult↗