Biomedical subjects

Nidhi Mahendra

Publications and source records attributed to Nidhi Mahendra.

4 recordsLinked to original sources

PubMed2005

Effect of presentation modality on immediate and delayed recall in individuals with Alzheimer's disease.

Episodic memory (EM) deficits are the hallmark of Alzheimer's disease (AD). Story-retelling tasks are particularly sensitive to EM impairments and require participants to recall a short story immediately and after a delay. The purpose of this study was to determine whether presentation modality influences story recall in AD participants. Thirty AD participants and 30 healthy elders recalled short stories in (a) auditory, (b) visual, and (c) combined auditory-visual modalities. Recall was assessed immediately as well as after 15- and 30-min delays. Presentation modality significantly influenced story recall in AD participants. AD participants demonstrated better recall after silently reading a story than after hearing an examiner tell the story or simultaneously hearing and reading the story. Clinical implications of these results are discussed.

Aged↗

PubMed2004

Exercise and volunteer work: contexts for AD language and memory interventions.

This article describes two novel contexts for language and memory stimulation in individuals with Alzheimer's disease (AD): student-supervised physical exercise and partnered volunteering at community agencies. Information presented is based on 5 years of the authors' experiences at the University of Arizona supervising student-administered interventions with mildly to moderately affected home-dwelling AD patients in the Volunteers in Partnership and Elder Rehab programs. The authors report significant mood and fitness improvements by program participants, as measured on direct testing as well as by caregiver perceptions regarding the relative benefits of the four program components. Finally, they advocate for greater use of nontraditional approaches and utilizing students and volunteers when working with persons who have AD.

Aged↗

PubMed2003

fMRI variability and the localization of languages in the bilingual brain.

The cerebral localization of multiple languages is a topic of active research. This study presents a method for assessing whether partial overlap of active voxels reflects differential language localization, or simply the variability known to occur with multiple runs of the same task in fMRI studies. Two groups of bilingual subjects (early and later learners of L2) performed word fluency and sentence generation tasks in both languages. The degree of separation for regions of activation did not exceed that associated with run-to-run variability for either task or either group. Early bilinguals, however, showed greater total numbers of active voxels than Late bilinguals for both tasks. This effect occurred despite a lack of a behavioral performance differences by the two groups.

Adolescent↗

PubMedDate not supplied

Effects of four years of exercise, language, and social interventions on Alzheimer discourse.

UNLABELLED: This article describes a comprehensive cognitive-linguistic intervention program for mild to moderate Alzheimer's disease (AD) patients that provided communication skills practice in the context of health-enhancing and esteem-building community-based activities: physical fitness training and supervised volunteer work. The interventions were administered by undergraduate students who completed academic work, received faculty supervision, and earned three credits for one semester of participation. Effects of the interventions on the discourse of four participants who completed all 4 years of the program are reported in detail. The maintained or improved performance on multiple discourse outcome measures provides powerful rationale for making such interventions more widely available and preliminary support for their effectiveness in preserving communicative function. An additional role for speech-language pathologists (SLPs)--as trainers and supervisors of non-professional rehab partners for persons with dementia--is proposed. LEARNING OUTCOMES: From this article, participants will be able to (1) list specific language tasks that can be used to assess discourse in individuals with AD; (2) identify several cognitive-linguistic interventions appropriate for use with AD patients; and (3) understand how long-term cognitive-linguistic interventions may affect the language performance of individuals with AD.

Aged↗