Biomedical subjects
Nigel Williams
Publications and source records attributed to Nigel Williams.
Towering tribute to botany.
One of the world's greatest plant collections has won a top heritage award at a time when it is highlighting with a tree-top walkway the need to study the forest canopy which is one of the most crucial but least understood habitats.
Not talking the talk.
The British government said it would consult the public on its decision whether or not to block the introduction of genetically modified crops following analysis of a series of field trials which will be completed this month. But their efforts have drawn scorn from the media and opponents as Nigel Williams reports.
Going, going, gone.
The decline and loss of species is inevitable in the face of growing human pressures on the environment but, according to one group of senior researchers, a standard framework is needed to assess the rate of this decline if researchers wish to be effective and policymakers are to take note.
Plight of the bumblebee.
One group of insects highlight some of the potential economic damage that loss of biodiversity may entail for the future of human food crops.
Say it with flowers.
Amongst Chelsea Flower Show's champion blooms last month, a range of diseased specimens helped flag up key plant research goals.
Ehlers-Danlos syndrome with severe early-onset periodontal disease (EDS-VIII) is a distinct, heterogeneous disorder with one predisposition gene at chromosome 12p13.
Ehlers-Danlos VIII (EDS-VIII) is an autosomal dominant disorder characterized by severe early-onset periodontal disease in conjunction with the features of Ehlers-Danlos syndrome (EDS). We performed a genomewide linkage search in a large Swedish pedigree with EDS-VIII and established linkage to a 7-cM interval on chromosome 12p13, generating a maximum multipoint LOD score of 5.17. Analysis of four further pedigrees with EDS-VIII revealed two consistent with linkage to 12p13 and two in which linkage could be excluded, indicating that EDS-VIII is a genetically heterogeneous disorder. Chromosome 12p13 has not previously been implicated in either EDS or periodontal disease and contains no known collagen genes or collagen-processing enzymes. Mutational screening of the microfibril-associated glycoprotein-2 gene, a strong candidate within the minimal interval, did not reveal any likely pathogenic mutations.
Europe uneasy on stem cell developments.
A first round rejection of human stem cell research by the European Parliament has given supporters the jitters in member states keen to pursue the potential offered by the new field, shown by a recent landmark appeal court decision on stem cell therapy by a team of Britain's top judges.
Picture this.
Some human populations in south-east Asia have foraged for a living in shallow coastal waters for generations. Could their eyes have adapted to these challenging conditions?
US model pushed for UK managers.
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Scrutiny pressure on funding biases.
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Gene passport prospects raise concerns.
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