A case of dermatopathic lymphadenitis diagnosed by fine needle aspiration.
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Adult↗
Biomedical subjects
Nilotpal Chowdhury
Publications and source records attributed to Nilotpal Chowdhury.
Interobserver variation in breast cancer grading: a statistical modeling approach.
OBJECTIVE: To study random and the systematic error in breast cancer grading, to find the source of disagreements and measure the reliability of graders so that appropriate corrective action can be taken. STUDY DESIGN: Five independent observers graded 50 breast carcinoma slides from 50 consecutive breast cancer specimens according to the Nottingham criteria. The polychoric correlation was used to measure association. Stuart-Maxwell and McNemar tests were used to measure equality of thresholds. RESULTS: The polychoric correlation among observers was high (mean = 0.803, 0.712, 0.797 and 0.602 for the final grade, tubule formation, nuclear pleomorphism and mitotic figures, respectively). However, there were significant differences in thresholds (6, 7, 7 and 9 pairs of 10 showing significant differences in classification of grades/scores for final grade, tubule formation, nuclear pleomorphism and mitotic counts, respectively). CONCLUSION: The high polychoric correlations suggest that random error in grading breast cancers in this study was low, confirming the underlying reliability of grading and graders. However, significant differences in the thresholds lowers raw agreement. Such a scenario may be rectified by increased intradepartmental discussion.
Breast Neoplasms↗
Cytomorphological features of combined myxoid and round cell liposarcoma--a case report.
Fine needle aspiration cytology plays an important role in the preoperative assessment of soft tissue neoplasms. In a 40-year-old man presenting with a large soft tissue mass in the posterior aspect of thigh a diagnosis of myxoid liposarcoma was suggested on FNAC. Scrape smears of the excised mass showed an additional finding of round cell component. Histopathology confirmed combined myxoid and round cell liposarcoma (grade 2), which behaves aggressively when compared to pure myxoid liposarcoma.
Adult↗