Biomedical subjects

Niphon Chirapapaisan

Publications and source records attributed to Niphon Chirapapaisan.

3 recordsLinked to original sources

PubMed2005

A traumatic bitemporal hemianopia with macular sparing.

Traumatic chiasmal syndrome is a rare complication of closed head trauma. It often presents as bitemporal hemianopia and may be associated with other neurological signs. The authors report a case of a 47-year-old man who had sustained severe frontal head trauma from a motor vehicle accident that caused multiple cranial fractures and prolonged loss of consciousness. He was subsequently diagnosed with traumatic chiasmal syndrome. Tangent field testing revealed bitemporal hemianopias with some macular sparing. Macular sparing was not found on the central 30-2 pattern of Humphrey visual field test.

Accidents, Traffic↗

PubMed2003

Optic neuritis: characteristics and visual outcome.

OBJECTIVE: To determine clinical characteristics of patients with optic neuritis and visual outcome after intravenous methylprednisolone treatment. METHOD: A total of 81 patients with optic neuritis were reviewed retrospectively with regard to their clinical characteristics by dividing into two groups as follows: group I had isolated optic neuritis and group II had optic neuritis with demyelinative disease. The visual outcome in these patients before and after intravenous methylprednisolone treatment was analyzed. RESULTS: Of 81 patients with optic neuritis, 63 patients (77.8%) had isolated optic neuritis and 18 (22.2%) patients were optic neuritis with demyelinative disease. The ages of the patients ranged from 16 to 59 years (mean = 35.3 years) in patients with isolated optic neuritis and from 16 to 73 years of age (mean = 35.8 years) in patients with optic neuritis with demyelinative disease. After treatment, 45 patients (52 eyes) with isolated optic neuritis and 14 patients (25 eyes) with optic neuritis with demyelinative disease who were followed-up for more than 10 days were studied. After treatment, 60 per cent of the isolated optic neuritis patients and 24 per cent of the optic neuritis patients with demyelinative disease had a visual acuity of 6/12 or better respectively. The isolated optic neuritis who had an onset interval to treatment of less than 8 days had a visual acuity better than 6/9 in 75 per cent. CONCLUSION: The final visual outcome in patients with isolated optic neuritis who received earlier treatment was better than those who received treatment later.

Adolescent↗

PubMed2002

A prospective randomized trial of megadose methylprednisolone and high dose dexamethasone for traumatic optic neuropathy.

PURPOSE: To determine whether the improvement in visual acuity obtained when using high dose dexamethasone in the treatment of traumatic optic neuropathy was comparable to that of megadose methylprednisolone. METHOD: A total of forty-four patients with traumatic optic neuropathy were prospectively randomized and selected to receive intravenous high dose dexamethasone or megadose methylprednisolone within 2 weeks of injury. Age, gender, cause of injury, interval from injury to treatment, initial, post-pulse, and final visual acuity were analysed statistically to compare the dexamethasone and methylprednisolone groups. RESULTS: The mean interval to treatment was not significantly different (p=0.28) for the dexamethasone group at 5.5 days compared to the methylprednisolone group at 4.1 days. Visual improvement of at least two lines of the Snellen chart or two levels of unmeasured visual acuity was shown in 9 patients (37.5%) of the dexamethasone group and 10 patients (50%) of the methylprednisolone group. There was no statistically significant difference between the initial and post-pulse visual acuity (p=1.0) and the initial and final visual outcome (p=0.60) in the dexamethasone group compared with the methylprednisolone group. CONCLUSION: There was no significant difference in the visual acuity obtained after treatment with intravenous dexamethasone or methylprednisolone for traumatic optic neuropathy.

Adolescent↗