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Nisar Khan

Publications and source records attributed to Nisar Khan.

6 recordsLinked to original sources
PubMedDate not supplied

Presentation of pulmonary tuberculosis at Ayub Teaching Hospital Abbottabad.

BACKGROUND: Pulmonary tuberculosis (PTB) may be easily confused with other chest diseases during its initial presentation. This study was carried out to identify presenting clinical and laboratory features that differentiate PTB from other diseases and to correlate clinical features and laboratory findings. METHODS: This study was carried out at the Department of Pulmonology, Ayub Teaching Hospital Abbottabad, from September 1999 to December 2000. A total of 46 patients were included in the study after being clinically diagnosed as pulmonary tuberculosis. These patients were subjected to detailed history taking recording age, sex, weight, socioeconomic status and smoking habits. They were clinically evaluated and laboratory tests including Hemoglobin, ESR, TLC, DLC and sputum for AFB were done. They were put on standard antituberculous therapy and followed from 2 to 5 months to monitor treatment effect. Statistical analysis was performed by SPSS 8 computer program. RESULTS: A bimodal presentation (below age 30 years and above age 50 years), fever, productive cough, weight loss, night sweats and raised ESR were the most common findings in PTB patients. Sputum AFB smears were positive in 50% of diagnosed cases. No correlation was found between clinical and laboratory parameters in establishing a confident diagnosis of the disease. CONCLUSIONS: The study highlights the importance of further research to pinpoint stronger and more reliable criteria for diagnosis.

Adolescent↗
PubMedDate not supplied

Efficacy, safety and tolerability of streptokinase in multiloculated empyema.

BACKGROUND: Empyema thoracis is a common illness with significant morbidity and mortality. Standard treatment of Empyema includes tube drainage and antibiotics. But the tube drainage often fails if the fluid is loculated. Intrapleural Streptokinase has been used in multiloculated empyemas with good success rate. We evaluated the efficacy and safety of intra-pleural Streptokinase in loculated empyemas. METHODS: A total of 15 patients admitted in Pulmonology unit with multiloculated empyemas whose drainage via drainage tube was less than 100 ml during the last 24 hours were included in the study. Aliquots of 250,000 units of Streptokinase in 100 ml of normal saline were instilled into the pleural cavity and the tube clamped for 3 hours. Response was assessed by clinical outcome, measurement of drain output after unclamping and subsequent chest radiography and serial chest ultrasounds. RESULTS: Streptokinase enhanced drainage in all patients with complete resolution of Empyema in 13 patients. Two patients with thickened visceral pleura following empyema drainage were referred to thoracic surgeon for decortication. The number of instillations of Streptokinase per patient ranged from 1 to 3 and the volume of drained empyema fluid ranged from 60 ml to 600 ml per patient. Streptokinase was well tolerated in all patients. CONCLUSION: Intrapleural Streptokinase is a safe and effective means of increasing the tube drainage in multiloculated Empyema without causing systemic fibrinolysis.

Adolescent↗
PubMedDate not supplied

Tuberous sclerosis--rare presentation as pneumothorax.

Pulmonary disease is a rare manifestation of Tuberous Sclerosis. We report a case where the patient presented with seizures, shortness of breath, popular lesions on the face and warty growths over the skin. She was intubated and the lung expanded on the 7th day after a longstanding pneumothorax of 3 months.

Adult↗
PubMedDate not supplied

Performance of ICT-TB test in the detection of pulmonary and extra-pulmonary tuberculosis.

BACKGROUND: Tuberculosis is a major public health problem of the developing nations including Pakistan. We need a simple, economical and non invasive test to make an early diagnosis of T.B. in order to avoid the complications. METHODS: A study was conducted at the Dept. of Pulmonology, PGMI LRH Peshawar & Ayub Teaching Hospital Abbottabad with the collaboration of Dept of Pathology KMC Peshawar from Jan 1998 to Dec 2002. A total of 129 patients were included in the study. Out of these 129 patients 52 were pulmonary TB (PTB) smear positive, 30 were PTB smear negative, 30 pleural effusion & 17 were TB lymphadenitis. The control group consisted of 25 non TB patients and healthy subjects. RESULTS: Antibody was detected in 23 of 52 (44%) sputum positive patients, 11 of 30 (36%) sputum negative PTB patients, 10 of 30 (20%) patients of TB pleural effusion and 6 of 17 (35%) patients of TB lymphadenitis. Antibody was detected in none of the control subjects. The overall sensitivity for Pul-T.B. Sputum positive patients was 44%, 36% for sputum Negative Pulmonary TB, 20% for TB pleural effusion and 35% for TB lymphadenitis. The specificity was 100%. CONCLUSION: ICT-TB is a highly specific, but less sensitive aid in the diagnosis of Pulmonology and extra Pulmonolgy TB.

Antibodies, Bacterial↗
PubMedDate not supplied

Etiology, presentation and management outcome of pneumothorax.

BACKGROUND: This study was carried to determine etiology, presentation, complications and management outcomes of pneumothorax in patients presenting at two hospitals in NWFP province of Pakistan.. METHODS: Pneumothorax patients reporting at the chest unit of Post Graduate Medical Institute, Lady Reading Hospital, Peshawar, and Pulmonology unit of Ayub Teaching Hospital, Abbottabad from 1999 to 2002 were included in the study. Patients of all ages were included. They were admitted and followed up to the full recovery/late complications. RESULTS: A total of 146 pneumothorax patients reported during this period. Majority of the patients were diagnosed to have pneumothorax due to pulmonary tuberculosis making about 36.30% of the total cases. Second most common cause was primary spontaneous pneumotihorax (19.86%). Bacterial infections were also sizeable at 16.43%. Other causes included COPD, Asthma, latrogenic, Interstitial lung disease, tuberous sclerosis and bronchiectasis. CONCLUSION: It was concluded from this study that pulmonary tuberculosis is the commonest cause of pneumothorax in our setup.

Adolescent↗