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Nobuyoshi Matsushima

Publications and source records attributed to Nobuyoshi Matsushima.

5 recordsLinked to original sources
PubMed2002

Autoimmune pancreatitis successfully treated with ursodeoxycholic acid.

A 51-year-old woman with autoimmune pancreatitis is reported in whom treatment with ursodeoxycholic acid (UDCA) was beneficial. Complaining of epigastric discomfort, she presented with liver dysfunction of the cholestatic type, and diabetes mellitus. Pancreatic imaging revealed a diffuse swelling of the body, an irregular narrowing of the main pancreatic duct, and a terminal stricture of the common bile duct. Histologically, the biopsied pancreas was replaced by fibrous tissue with a small amount of mononuclear cell infiltration. She had anti-carbonic anhydrase-II antibody and anti-lactoferrin antibody. After treatment with UDCA, her liver dysfunction and diabetes mellitus improved and the pancreas size was reduced. Steroid therapy is usually indicated for this disorder, but UDCA may be given as an alternative choice.

Angiography↗
PubMedDate not supplied

Recanalization and reversal of diffusion abnormalities and markedly reduced cerebral blood volume in a patient with transient ischemic attack.

Resolution of diffusion abnormalities is a finding that is rarely seen in hyperacute cerebral ischemia. We report a serial study of diffusion and perfusion magnetic resonance imaging (MRI) in a case of transient ischemic attack (TIA). In the current case, marked decrease of cerebral blood volume (CBV) as well as reduced diffusion in the affected middle cerebral arterial territory was shown by the initial diffusion and perfusion MRI at 1.5 h after onset. The initial MRI findings as well as neurological symptoms recovered probably due to prompt and spontaneous recanalization of thrombosed vessel.

Aged↗