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Biomedical subjects

Nupur Gupta

Publications and source records attributed to Nupur Gupta.

6 recordsLinked to original sources
PubMed2006

Creation of neovagina using oxidized cellulose (surgicel) as a surgical treatment of vaginal agenesis.

OBJECTIVE: Our goal was to analyze the safety and efficacy of the use of oxidized cellulose in the creation of neovagina. METHODS: A total of 10 women with vaginal agenesis attending gynaecology clinic of AIIMS between July 2003 to March 2005 underwent vaginal reconstructive surgery using oxidized cellulose were recruited in this retrospective study. The age of patients ranged from 17 to 22 years (mean age 19 years). Using a transverse incision at introitus, a 10 x 4 cm space was created and a vaginal mould covered with oxidized cellulose was put in the neovagina. RESULTS: The age ranged from 16 to 22 years (mean 19.5 years). Out of 10 patients, who had undergone vaginoplasty, all were sexually active; 8 had satisfactory intercourse, 1 chronic mild dyspareunia due to partial stenosis and 1 was lost to follow up. 2 out of 10 had inflammatory reaction and 1 had psychological problems. CONCLUSION: Vaginal reconstruction using oxidized cellulose appears to be a safe and effective procedure with minimum complications, morbidity and discomfort with high success rates.

Adolescent↗
PubMed2006

Advances in hormonal contraception.

This article presents a review of advances made in hormonal contraception over the past 15 years. It looks at the different routes of administration that have been developed, at newer formulations of conventional methods, and at novel contraceptive agents that are in the process of approval. The article provides a short description of each of these contraceptive methods, information about compliance, side effects, and efficacy, and an update on that particular method.

Administration, Cutaneous↗
PubMed2005

Acute promyelocytic leukemia: an unusual cause of fatal secondary postpartum hemorrhage.

INTRODUCTION: Postpartum haemorrhage can rarely be associated with an underlying coagulation or haematological disorder. We wish to discuss a case of acute promyelocytic leukemia (APL) presenting as secondary postpartum hemorrhage (PPH), its clinical and pathological features and maternal outcome. CASE REPORT: We describe a 28-year-old woman who presented with secondary PPH accompanied by bleeding from gums, marked pallor, hematemesis, ecchymotic and purpuric spots all over the body, 8 days post-partum. Investigations revealed her to be having APL, a diagnosis not suspected by the referring clinic. She was given supportive therapy but died before chemotherapy could be started. CONCLUSION: The case emphasizes the importance of suspecting, investigating and energetically treating uncommon causes such as acute leukemia when an unusually severe clinical picture in a postpartum setting suggests such a possibility. This may prove to be life saving, particularly if the leukemia happens to be APL, a cancer with a very high cure rate.

Adult↗
PubMed2005

Successful closure of a bladder neck fistula complicated by urethral and vaginal stenosis, using oxidized cellulose (Surgicel) for reinforcement.

We describe a case of a bladder neck fistula in a 25-year-old lady presenting with true urinary incontinence, vaginal constriction and induration, with vaginal length reduced to only 1.5 cm. There was an 8-mm fistula involving upper urethra and bladder neck, with fibrosis all around. Using Schuchardt incision, the fistula was reached and mobilization tried. As there was less available tissue, a 3 x 2-cm layer of oxidized cellulose was stitched between the bladder and the vaginal mucosa for reinforcement and to achieve a watertight closure of fistula.

Adult↗
PubMed2005

Extraskeletal osteochondroma of the thigh: a case report.

A case of histopathologically proven extraskeletal osteochondroma of the thigh is presented along with its radiographic, CT and MRI findings. This is the first such case reported, to the best of our knowledge. The diagnosis of extraskeletal osteochondroma should be considered when a discrete ossified mass is localised in the soft tissue.

Adolescent↗