PubMed Health⌕ Search

Biomedical subjects

O A Kiseleva

Publications and source records attributed to O A Kiseleva.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

[Results of a morphological study of the experimental use of polyglycolide fiber explants in the surgery of retinal detachment].

The paper presents the results of experimental use of a polyglycolide material-based filling for temporary episcleral filling in retinal detachment. Thorough comparative morphological and biomechanical studies of 120 experimental eyes in different periods after scleroplasty, by using an inflatable balloon catheter, homoscleral and polyglycolide fillings, have indicated that the polyglycolide filling material is completely lysed by ocular tissues within 60-90 days, which rules out a repeated surgical intervention for removal of temporary filling (for example, an inflatable balloon catheter), by preserving the constancy of the depth of scleral pressing-in. The short existence of a chemically indifferent polyglycolide filling in the ocular tissues excludes its negative effect on the surrounding structures of the eye, minimizes the likelihood of the occurrence of early postoperative complications, but thereby leading to a substantial increase in the biochemical stability of the scleral-and-chorioretinal complex in the early postoperative periods and ensuring increased resistance to dynamic loads, by forming a stable scleral-and-chorioretinal adhesion 3 months after surgery. The findings suggest that the designed polyglycolide explant has advantages and that it is expedient to introduce the new Russian resolving polyglycolide fiber explants into clinical practice (for scleroplastic operations).

Absorbable Implants↗
PubMedDate not supplied

[Development of a system for assessment of work performance and quality during therapeutic-diagnostic processes in ophthalmology].

A system for estimating labor consumption in, and quality of the therapeutic and diagnostic process, based on the medicosocial and economic analysis of the current ocular morbidity structure in Russia, is suggested. This estimation system may be useful in condition of cost accounting relations introduction in research institutions of ophthalmologic profile.

Humans↗
PubMedDate not supplied

[Problems in transferring a research institute of ophthalmology to new economic system].

Introduction of new economic principles in the activities of medical research institutions helps extend the rights and responsibilities of the institutes' stuff and make them economically interested in the results of their activity; these principles provide high quality of treatment and prophylaxis work and permit concentrating all the resources on the priority trends in medical research. The authors discuss the pressing problems in introducing the cost accounting system in the activity of a research institute in ophthalmology.

Academies and Institutes↗
PubMedDate not supplied

[Possibilities of diet therapy in the correction of hypercholesterolemia in patients with ischemic heart disease under outpatient conditions].

Diet therapy conducted in 135 patients with coronary heart disease resulted in the reduction (68.9% of cases) and normalization (49.6% of cases) of the total cholesterol level in the blood (TCS). The lowering of TCS level, as a rule, was combined with the diminution of triglyceride level in the blood and reduction of the initial excessive body mass. To correct the shifts in lipid metabolism, it was enough to make relatively insignificant changes in nutrition: to exclude the products too rich in cholesterol, to restrict the consumption of hard fats, to increase the content of vegetable oils and food fibres in the ration. A total of 13 out of 30 patients who were followed up by the dietitian during 1-7.5 months after the second visit returned to their routine type of nutrition that was attended by a rise in TCS content in the blood. No effect of the diet therapy was recorded in a small number of patients.

Adult↗
PubMedDate not supplied

[A clinical case. A case of bilateral retinal detachment after scleroplasty].

After prophylactic scleroplasty for high complicated myopia the patient developed bilateral detachment of the retina. Therapeutic strategy with this patient is followed up. The described clinical case evidences the necessity of a strict validation of the choice of this or that surgical modality, particularly in cases when it concerns the only eye with vision.

Humans↗
PubMedDate not supplied

[Clinico-immunologic indices in chronic pancreatitis patients and changes in them during diet therapy].

Study of the clinical and immunological indicators in 101 patients with chronic recurrent pancreatitis has demonstrated that 98.5% of the examined were sensitized to pancreatic antigen (according to the data of the different tests of cell immunity). The total immunological responsiveness in chronic pancreatitis patients did not differ from that in normal subjects. After treatment with antipancreatic mechanically and chemically sparing diets containing 80-90 g fat, 300-350 g carbohydrates and 140-150 g protein (diet 1P) and 110-120 g protein (diet 2P) there was a positive time course of the clinical symptomatology and of a number of biochemical indicators, as well as a decrease in the sensitization to pancreatic antigen and an increase in the total immunological responsiveness. Application of the diet containing 110-120 g protein produced a more demonstrable reduction in the degree of specific sensitization, correlating with a more favourable time course of the patients' status. At the same time application of the diet containing 140-150 g protein gave rise to a more substantial rise of the total immunological responsiveness. The conclusion is made about high efficacy of the antipancreatic diets, particularly of the diet containing 110-120 g protein and about the advisability of the use of the immunological tests for the appraisal of the general status of patients, activity of the pathological process in the pancreas, and the efficacy of the treatment.

Adult↗
PubMedDate not supplied

[A new method of formation of chorioretinal adhesions in retinal detachment].

A method of intrascleral transplantation of foam gel providing the creation of stable chorioretinal adhesion at the site of the retinal defect has been experimentally developed and clinically tried. A special injector has been designed for the realization of the method, permitting stratification of the scleral capsule at a given depth. The suggested method is recommended for practical use in patients with rheumatogenic detachment of the retina in the initial and moderate degrees of vitreoretinal proliferation.

Choroid↗
PubMedDate not supplied

[Experimental morphological study of posttraumatic proliferative vitreoretinopathy prevention by cell adhesion peptide Arg-Gly-Asp-Ser].

Proliferative vitreoretinopathy (PVR) was induced in 25 rabbits by injection of autologous adenosine phosphate-activated platelets in the vitreous. Injury to the internal interface retinal membrane as a result of adhesion of aggregated platelets to it, followed by the formation of an epiretinal membrane, underlies the morphogenesis of experimental PVR. Proliferative processes in the retina were paralleled by destructive atrophic changes in it, which might be due to active physiological substances released in the course of aggregation. The development of PVR was inhibited by a synthetic peptide of cell adhesion with Arg-Gly-Asp-Ser amino acid sequence, which was injected simultaneously with autologous activated platelets. Possible receptor mechanisms underlying the phenomenon of inhibition of the proliferative process in the retina of experimental animals are discussed.

Animals↗