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Biomedical subjects

O A Mashkov

Publications and source records attributed to O A Mashkov.

At least 19 recordsLinked to original sources
PubMed1993

[The treatment of psoriasis by efferent methods on an outpatient basis].

In addition to conventional outpatient treatment 165 psoriasis patients underwent hemosorption (100 cases) or plasmapheresis (65 cases). The efferent methods used proved beneficial in 99 (60%) of the patients that got to have normal hemograms, reduced CIC and middle molecular weight peptides levels in blood. The response depended on the disease duration irrespectively of the method of efferent treatment. The remission (1-2 years) was achieved in 79 (48%) of the patients treated who developed neither side effects no complications. Compared to controls on hospital routine therapy, a mean decrease in treatment duration made 10 +/- 4 days. Efferent outpatient treatment of psoriasis is recommended for patients with torpid course of the disease and for those who is ill not longer than 5 years.

Adolescent↗
PubMed1991

[The initial clinical experience of using Ovosorb antiprotease hemosorbent in the combined treatment of dermatoses].

The new antiprotease hemosorbent Ovosorb was tested during the performance of blood perfusion (BP) used as part of multimodality treatment of 11 patients. Of these, 2 presented with disseminated psoriasis, 3 with arthropathic psoriasis, 1 with psoriatic erythrodermia, 4 with atopic dermatitis, and 1 with recurrent urticaria. BP with the use of the hemosorbent Ovosorb produced the highest effect in patients with atopic dermatitis, psoriatic erythrodermia and recurrent urticaria; BP with Ovosorb was less effective in disseminated psoriasis. The clinical effect was lacking in patients with arthropathic psoriasis. Ovosorb possesses remarkable detoxifying properties, good blood compatibility; it does not provoke any complications in patients with different forms of psoriasis, atopic dermatitis, and urticaria.

Acrylic Resins↗
PubMed1991

[Effect of enterosorption on the course of psoriasis].

Monthly courses of enterosorption given to 23 elderly and senile patients provided a remarkable clinical effect, especially in patients with skin lesions of the hairy part of the head and with seborrhea. Positive changes were recorded in lipid disorders. Administration of the enterosorbent does not lead to any complications, exerts a beneficial effect on the body, promotes polypragmasia reduction.

Aged↗
PubMed1989

[Enterosorption in the combined therapy of psoriasis patients].

The authors consider the clinical efficacy of enterosorption, carried out in 112 patients with various forms of psoriasis. Indications for and contraindications to this treatment modality are defined. Changes in the level of endogenous intoxication in the paramecium test over the course of enterosorption treatment are analyzed.

Adolescent↗
PubMed1980

[Hemo- and lymphosorption in cardiogenic shock (an experimental study)].

The important role of toxemia in the pathogenesis of cadiogenic shock was demonstrated in 38 experiments on dogs. It was found that the blood becomes toxic later than the lymph. Lymphosorption arrests the progress of toxemia but does not relieve it if it has already developed. The hemosorption method produced a good effect. Studies showed, however, that it does nor prevent the arrival of lymph with a high toxin content. The best effect was produced when lympho- and hemosorption were combined under conditions of stimulation of lymph production and lymph drainage.

Animals↗
PubMed1977

[Possiblity of using immobilized urease for degradation of urea in blood plasma].

As revealed the velocities of urea decomposition in the citrate donor plasma with soluble urease and urease immobilized by addition to carboxymethyl ester of cellulose, 2-(3'-amino-4'-methoxyphenyl)-sulphonylethyl ester of cellulose, diethylaminoester of cellulose, stained with dichlortriazine stain, or graft copolymere of cellulose and polyglycidylmetacrylate were sufficiently close to one another. Preparations of immobilized urease can be repeatedly used for urea decomposition in the citrate donor blood. Periodical treatment of the mentioned preparations with cystein solution led to a lesser decrease of enzymatic activity of the immobilized urease after repeated use.

Blood Preservation↗
PubMedDate not supplied

Physicochemical properties and applications of carbon-mineral sorbents.

Carbon-mineral sorbents successfully combine a high mechanical resistance of the mineral matrix and a high activity of carbons. It is possible to prepare a mineral matrix of the wanted structure and use it as the basis for producing carbon-mineral sorbents. SUMS-1 and SUMS-2 are the sorbents of mild action. In other words, they cause no thrombosis, they do not absorb oxygen and protein from blood, and they have almost no destructive effect on the blood cells. The sorbents are highly effective in adsorbing microorganisms and their toxins. Treatment of patients with different diseases (sepsis, meningitis, bronchial asthma, tuberculosis, pneumonia, thyrotoxicosis, pancreatitis, liver coma, different types of poisoning) with the SUMS-1 and SUMS-2 has given satisfactory results.

Adolescent↗