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Biomedical subjects

O A Ojo

Publications and source records attributed to O A Ojo.

At least 19 recordsLinked to original sources
PubMed1982

Plasma high-density-lipoprotein cholesterol levels during long-term use of an oral contraceptive in Nigerian women.

Total and high-density lipoprotein (HDL) cholesterol were estimated in 131 blood samples obtained from women who had been taking the oral contraceptive Noriday 1 + 50Fe (one packet contains 21 tablets of 1 mg of norethindrone + 0.05 mg of mestranol, and 7 of 75 mg of ferrous fumarate) for 1-60 months. Thirty five women who had never used oral contraception (OC) formed the control group. There was a significantly higher mean HDL cholesterol level, and HDL cholesterol/total cholesterol ratio but not total cholesterol level in the women who had been using OC for 19-60 months. The values in women who had been using OC for 1-18 months were not significantly different from those in the control group. The increase in the HDL cholesterol level may not depend on the oestrogen content of the oral contraceptive but on the duration of its intake.

Adult↗
PubMed1982

Serum vitamin A, carotene and cholesterol levels in Nigerian women using various types of contraceptives.

The diet in southern Nigeria is unusually high in carotenoids and low in preformed vitamin A. We studied the changes in serum vitamin A carotene and cholesterol induced in women in this region by the use of 3 types of contraceptives: IUD, injectable progestogen (INJ), and oral combination estrogen-progestogen (OC). The mean serum vitamin A and carotene levels were high in all groups. As expected, the serum vitamin A level in OC users was higher than in the other groups, but unexpectedly, the serum vitamin A was lower in IUD users. Serum carotene was lower in OC users than in other groups. Serum cholesterol was lower in the IUD and INJ groups than in the control and OC groups. A more detailed study of plasma transport forms of vitamin A is needed to determine if the very high serum vitamin A levels seen in some OC users in this population are potentially harmful.

Africa↗
PubMed1978

Menstrual regulation in Ibadan, Nigeria.

Menstrual regulation (MR) (i.e., vacuum aspiration of the uterus with a small diameter, flexible cannula before pregnancy can be determined by a conventional pregnancy test) has been proven safe and effective in many clinics around the world. The present study, which we believe is the first such study of MR in Subsaharan Africa, shows that, for women in an urban African setting, MR is an acceptable backup for other contraceptive methods. Data on 507 MR patients treated at the University College Hospital in Ibadan, Nigeria, between January 1974 and April 1976, showed that the procedure was both safe and effective for 93.4% of the study subjects: there was an overall complication rate of 3.4% and MR failed in seven cases (3.2%). Data also showed that MR is an effective method of recruiting new contraceptive acceptors, as well as an effective back-up procedure in case of contraceptive failure.

Adult↗
PubMed1969

Arterial pressures in rural and urban populations in Nigeria.

Surveys of arterial pressure carried out in rural and urban communities in Western Nigeria showed a steady rise in systolic values with age, this trend being less marked with diastolic pressures. Blood pressure levels were similar in women from rural and urban areas, but seemed much higher in urban than in rural men. The incidence of proteinuria was lowest in the female urban group. In general, the incidence of proteinuria or glycosuria was low and did not appear to be related to the blood pressure.

Adolescent↗