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Biomedical subjects

O A Saatci

Publications and source records attributed to O A Saatci.

10 recordsLinked to original sources

Unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization in Crohn's disease.

PURPOSE: To report on a case of Crohn's disease and unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization. METHODS: We examined a 38-year-old woman with severe left visual loss and biopsy-proven Crohn's disease diagnosed four years prior to the ocular involvement. A Heidelberg scanning laser ophthalmoscope was used for fundus fluorescein angiography and indocyanine green angiography. Retinal neovascularization was detected during the follow-up. RESULTS: Successful regression of retinal neovascularization was achieved after argon green laser panretinal photocoagulation in addition to oral steroid and salazopyrine. CONCLUSION: Retinal vascular involvement is a rare ocular feature of Crohn's disease and may result in retinal neovascularization that may necessitate prompt laser photocoagulation.

Adult↗

An unusual central retinal dystrophy associated with ichthyosis vulgaris.

A number of ichthyosis syndromes may have retinal abnormalities such as the retinitis pigmentosa-like diffuse rod-cone dystrophy in Refsum's syndrome and the maculopathy in Sjögren-Larsson syndrome. We present two sisters who have an unusual, almost identical, bilaterally symmetric central retinal dystrophy associated with ichthyosis vulgaris in the absence of other systemic disorders. We believe that this dystrophy has not been previously described in patients with any of the known varieties of ichthyosis.

Adolescent↗

Underlying pathologies in secondary strabismus.

PURPOSE: In this prospective cross-sectional observational study, the distribution of organic pathologies in patients initially presenting with strabismus was evaluated. METHODS: Thirty-one of 243 patients examined between May 1997 and May 1998 had strabismus due to organic causes and 28 patients had posterior segment abnormalities. RESULTS: Toxoplasma chorioretinitis, morning glory anomaly, toxocara retinopathy, retinopathy of prematurity and Coats' disease were the most common diagnoses. Eighteen patients (58%) had esotropia and 13 (42%) had exotropia. The mean age of onset of deviation was significantly lower in the esotropic patients. There was no correlation between the degree of visual impairment and direction of deviation. CONCLUSIONS: Our study strongly underlines the importance of fundus examination in each strabismic patient.

Age of Onset↗

Pseudoexfoliation and glaucoma in eyes with retinal vein occlusion.

PURPOSE: To evaluate pseudoexfoliation (PE) and pre-existent glaucoma in eyes with branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO). METHODS: Consecutive eyes with a diagnosis of BRVO (73 eyes of 70 patients) and CRVO (53 eyes of 49 patients) examined between July and December 1998 comprised the study eyes. Age-matched control group consisted of 384 eyes of 192 outpatients. The prevalence of PE and glaucoma were determined and appropriate statistical tests were performed. RESULTS: PE was present in six of 73 eyes with BRVO (8.2%), 11 of 53 eyes with CRVO (20.8%) and 20 of 384 control eyes (5.2%). Two of 73 eyes with BRVO (2.7%) and 10 of 53 eyes with CRVO (18.9%) had glaucoma. Compared with the control eyes, PE was significantly more common in eyes with CRVO and coexistent glaucoma was significantly more common both in eyes with CRVO and in eyes with BRVO. CONCLUSION: While glaucoma seems to be a risk factor both for BRVO and CRVO, PE is a likely risk factor for CRVO.

Adult↗

Posterior chamber intraocular lens implantation in eyes with inactive and active proliferative diabetic retinopathy.

We reviewed the records of 2,100 consecutive eyes that had undergone extracapsular cataract extraction with intraocular lens implantation between January 1981 and December 1989. Of these eyes, 21 had inactive and four had active proliferative diabetic retinopathy at the time of cataract extraction. Twenty-one eyes with inactive proliferative diabetic retinopathy received extracapsular cataract extraction with posterior chamber intraocular lens implantation, and four eyes with active proliferative diabetic retinopathy had both extracapsular cataract extraction with posterior chamber intraocular lens implantation and pars plana vitrectomy with endophotocoagulation. The mean follow-up period was 27 months. Final visual acuity was 20/40 or better in 12 of 25 eyes (48%). Of 25 eyes, five (20%) showed progression of the retinopathy after the operation, and two (8%) developed macular edema. Extracapsular cataract extraction and posterior chamber intraocular lens implantation was well tolerated in most eyes.

Adult↗

Extracapsular cataract extraction with intraocular lens implantation after scleral buckling surgery.

We reviewed the records of 28 patients who had undergone successful scleral buckling surgery followed by extracapsular cataract extraction with implantation of an intraocular lens. Posterior chamber intraocular lenses were inserted in 27 eyes, and anterior chamber intraocular lenses were inserted in two eyes with posterior capsule rupture at the time of surgery. The mean follow-up period was 44 months. Final visual acuity was 20/40 or better in 15 of 29 eyes (52%). One eye (3.4%) developed a recurrent retinal detachment 15 months after cataract surgery. Two eyes (6.9%) developed angiographically proven cystoid macular edema. The outcome for extracapsular cataract extraction with intraocular lens implantation in eyes that had previously undergone successful scleral buckling for retinal detachment is favorable.

Adult↗

Chloroquine and hydroxychloroquine retinopathy: how to follow affected patients.

The retinopathy caused by antimalarials is well known. The differences between antimalarials and daily and cumulative doses are important factors in predicting the development of retinopathy. None of the commonly used tests alone are satisfactory for detecting early retinal changes. We recommend baseline color fundus photographs and automated central visual fields to follow these patients every nine to 12 months. Between these examinations, Amsler grid testing is adequate for screening for early defects.

Chloroquine↗

Visual outcome in pseudophakic eyes with clinical cystoid macular edema.

Thirty-nine eyes with clinical cystoid macular edema (CME) following extracapsular cataract extraction and intraocular lens (IOL) implantation were reviewed retrospectively. Chronic CME, defined as clinically symptomatic CME persisting more than 6 months, developed in 14 of the 39 eyes (36%): in 5 of the 7 (71%) eyes in which vitreous loss occurred and anterior chamber IOLs were implanted; and in 9 of 32 (28%) eyes in which no complications occurred and posterior chamber IOLs were implanted. The mean duration between diagnosis and last follow-up visit was 34 months. Only 4 of the 14 eyes (29%) with chronic CME achieved a visual acuity better than 20/40. Vitreous loss did not affect long-term visual prognosis.

Aged↗