PubMed Health⌕ Search

Biomedical subjects

O A Varshavskaia

Publications and source records attributed to O A Varshavskaia.

4 recordsLinked to original sources

[Crystallization effects in serum high density lipoproteins].

Peculiarities of aggregation in the samples of high density serum lipoproteins LHD2 and LHD3 obtained from healthy donors and patients with ishaemic heart disease were studied under isothermal exposition. It was found that lipoprotein samples from defective serum were characterized by chemical and structural inhomogeneity. It is reflected in the formation of spherolites of various types and of well-grown dendrite forms. Growth of stepped lens-shaped crystals of cholesterol takes place in the normal serum LHD3 preparations after long exposition. Crystal growth is thought to begin according to dislocational mechanism on linear defects existing in the liquid crystalline phase; then transformation to kinetically rough surface and to normal growth of the face occurs with the concentration increase.

Cholesterol, HDL↗

[Ordering of lipids and lipid-protein complexes in molluscan mucus and human bile].

Optic-morphological characteristics and crystallization of mucus of land snails Achatina fulica (Bowditch) are compared with cervical secret and also with the human bile. Typical defective structures of mesophases: spheroliths, regions of confocal and fan textures containing various classes of line defects are shown. Crystallization of protein and lipid fractions is shown to proceed separately, while the dendrite mechanism is typical for the former and for the latter the dislocational growth of crystals from the mesophase is possible.

Animals↗

[Defect structures of phospholipid lyotropic phases].

The relation between defect structures and peculiarities of relaxation processes at the formation of lyotropic phases in various phospholipid systems was studied. It is shown that both the structure faults and kinetics of textural transitions and cristallization depend on the saturation of fatty acid residues of lipids. It is established that the time range of lipid mesophases is increased while adding dimethylsulphoxid in all the systems studied.

Dimethyl Sulfoxide↗