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Biomedical subjects

O A Vorob'ev

Publications and source records attributed to O A Vorob'ev.

At least 19 recordsLinked to original sources

[Pharmacoprophylaxis of sea-sickness syndrome with the help of homeopathic drug "Avia-more"].

Anti-sea-sickness effect of a new homeopathic drug [see text] and its influence on operator's working capacity during Coriolis acceleration was evaluated in blind placebo-controlled investigation conducted in practically healthy volunteers with low vestibular resistance. For comparison "Dimenhydrinate" was used. The investigation has demonstrated that [see text] has rather strong anti-sea-sickness effect, is comparable with dimenhydrinate effectiveness and prevents the development of disorders in sensory-and-motor and cognitive functions during the influence of static-and- kinetic loads. According to the data obtained the protective action of [see text] is most likely connected with adaptive effect on organs and systems that form the functional protective system against sea-sickness. The negative influence of the drug on CNS complex functions was not observed that allows recommending its prophylactic use in subjects with low sea-sickness resistance including the operators.

Adolescent↗

[Problems of hearing loss in aviation engineers (professional and ecological aspects)].

Health standards for noise were exceeded 3 times when noise characteristics were measured at jobs and in apartments of engineers engaged in maintenance of modern aircraft. These specialists were exposed to noise in working hours and at night. Audiometry registered hearing problems in 69% of the examinees. 20% of them had hearing loss of the second degree. In engineers living closer to airports hearing was damaged more seriously, especially at frequencies 1000-8000 Hz. This fact demonstrates ecological implication of non-occupational acoustic load. Relevant regression levels were derived from correlation of noise doses with tonal hearing. Natural and experimental investigations proved efficacy of impedancemetry in objective assessment of noise-induced affection of the organ of hearing and hearing restoration in subjects occupationally exposed to noise.

Acoustic Impedance Tests↗

[Current aspects of the noise problem in aviation medicine].

The authors discuss the problem of improvement the noise factor prevention in aviation medicine. The analysis of the real acoustic load on aviation engineer specialists, performing maintenance of the modern military aircraft have been given. The authors show the importance of the approach to the aviation noise as an ecological significant factor, that means taking into account the acoustic load during work time as well as during rest-sleep periods. The authors suggested the advanced complex of the preventive measures for the purpose of optimization of the noise exposure on the aviation specialists.

Aerospace Medicine↗

[Intersensory interactions as the basis of methods in enhancing resistance to motion sickness].

The paper considers how to improve prophylactic measures for air motion sickness. It outlines the results of experimental investigations to substantiate vestibular selection and training methods based on the use of polysensory vestibular and visual stimulations, somatosensory afferent effects and mental activity in the flight personnel during exercise tests. The developed methods are shown to have a high efficiency in providing good tolerance of vestibular stimulations during flight under the conditions of higher flying educational establishments at the stage of primary flying training.

Adult↗

[Aviation noise as an ecological environmental factor].

Average diurnal doses of noise, received by aviation engineers servicing up-to-date aircrafts and living near air fields, were analyzed. The doses appeared to outnumber the normal values, especially during the work and the sleep. The examinees living in 1-2 km from air fields were proved to have significantly higher auditory thresholds for 1,000-8,000 Hz, in comparison with the examinees residing 5-6 km apart. The excessive noise associated with no occupational matters worsens the hearing restoration after the work, promotes accumulation of the hearing fatigue. Those facts were proved by experiments with audiometry and impedometry. The studies stressed the importance of aviation noise as ecologic factor.

Aircraft↗

[Effect of acceleration on the sugar content of rabbit cerebrospinal fluid].

The sugar content in the liquor of rabbits exposed to accelerations ranging from several minutes to several hours was studied. The animals were accelerated at 3 g in a centrifuge with a radius of 55 cm and a velocity of 70 rpm, in the Khilov's swing and in a rotating device simulating angular accelerations. The liquor was sampled by the suboccipital puncture and the sugar content was measured according to Hagedorn-Jensen. A statistically significant increase in the sugar content was noted after every exposure to accelerations of alternating signs than with accelerations of a constant value. The experiments on labyrinth-ectomized animals showed a certain effect of the vestibular analyzer on the carbohydrate metabolism. However, when the equilibrium function reached compensation, the sugar content in the liquor returned to the pretest level. Therefore, this reaction involves not only the vestibular system but also the optic, proprio- and interoceptive afferent systems. A comparison of the intracysternal and intramuscular injections of epinephrine points to the central (in contrast to the hematogenic) nature of an increase in the sugar content during the first minutes of acceleration. The electric stimulation of the anterior and posterior hypothalamus by means of implanted electrodes produced the same elevation of the liquor sugar as accelerations. It can be postulated that afferent impulses from the analyzer systems reach the hypothalamic centers, thus exciting the autonomic system and, first of all, the sympathic system.

Acceleration↗

[Spatial orientation of human on a background of +Gz loads and head movements].

Spatial orientation of six normal subjects (19-28 y/o males) was investigated on a centrifuge with a radius of 6.55 m by the method of subjective haptic vertical during head movements on the pattern of working head movements of pilots impacted by +Gz loads. The investigation showed that the trend and intensity of G-excess illusion could be related to the occurrence of tangential components of the gyroscopic moment +Gz vector in the utricle otolith plane.

Adult↗

[Effectiveness of hyperbaric oxygenation as a factor of increasing the resistance of the human body to space flight conditions].

In four experimental runs (30 test subjects in 407 tests), the beneficial effect of hyperbaric oxygenation (HBO) on flight tolerance was demonstrated. HBO sessions (7-8 sessions of an hour in duration during 10-12 days at pO2 = 2 atm) helped subjects with poor altitude tolerance to increase the altitude ceiling by 1 km and reserve time at altitudes of 6-7 km by 3-4 min, the effect being persistent for 2-3 months. Statokinetic tolerance of subjects with medium motion sickness susceptibility grew by 2-2.5 times after the above HBO sessions. As compared to regular rest, the HBO treatment shortened two-fold the period of recovery of the health state and work capacity of operators, which went down during flight, and increased 15-20% the time of repeated work prior to failure in a stressful environment.

Adult↗