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Biomedical subjects

O Abbasoglu

Publications and source records attributed to O Abbasoglu.

28 records · Page 2Linked to original sources
PubMed1995

A case of intraperitoneal pancreas.

A case of anomalous location of the pancreas is presented. In this case, head and a part of the body of the pancreas were found intraperitoneal. The pancreas was covered by the peritoneum within the omental bursa except its tail. Additionally, the anterior layer of the hepatogastric ligament turned over the hepatoduodenal ligament and continued behind the head of the pancreas together with the peritoneum which formed the posterior wall of the epiploic foramen (Winslow). The peritoneum also covered a part of the posterior surface of the body and directed to the right, forming a recessus just behind the pancreas.

Dissection↗
PubMed1995

The effect of the pineal gland on liver regeneration in rats.

BACKGROUND/AIMS: We investigated the influence of pinealectomy on liver regeneration after partial hepatectomy in rats. METHODS: Thirty rats were allocated into four groups as follows: group 1 in which no operation was done (control), group 2 in which only midline scalp incision and craniotomy was performed (sham operation), group 3 in which pinealectomy was performed and group 4 in which the rats underwent pinealectomy and pineal transplantation. Eight weeks later all the rats underwent 70% hepatectomy. RESULTS: Hepatic regenerative capacity was observed 24 h after PH by bromodeoxyuridine incorporation into DNA and the mitotic index of hepatocytes. The bromodeoxyuridine labeling indices were 45.4, 35.8, 19.9 and 36.8 in groups 1, 2, 3 and 4, respectively. The mitotic indices of the same groups were 31.2, 28.7, 8.3 and 13.4, respectively. Both the bromodeoxyuridine labeling and mitotic indices were significantly lower in the pinealectomized rats than in the control and sham operation groups. CONCLUSIONS: These results suggest that the pineal gland stimulates liver regeneration after partial hepatectomy in rats.

Animals↗
PubMed1993

Percutaneous treatment of abdominal hydatid cysts with hypertonic saline and alcohol. An experimental study in sheep.

RATIONALE AND OBJECTIVES: Seven naturally infected sheep with proper hepatic and peritoneal hydatid cysts were studied to assess a new percutaneous approach for cystic hydatid disease. METHODS: A needle was inserted into the cyst cavity of sheep under sonographic guidance. Immediately after instillation of hypertonic saline to inactivate protoscolices, ultrasound demonstrated that germinal and laminated membranes of the hydatid cysts were separated completely from the pericyst in all sheep. Later, a catheter was inserted into the cyst cavity using Seldinger technique. Alcohol was used as a sclerosing agent. RESULTS: Ultrasound showed reduction in cyst size and progressive solidification. No anaphylactic reaction was observed. After sonographic follow-up that lasted from 1 to 26 weeks, the sheep were killed to evaluate macroscopic and histologic changes. At autopsy, no secondary cyst formation was seen. The appearance of treated cysts was different from the others, and there were signs of involution. The histologic sections did not show any viable protoscolices or daughter cysts. The authors observed pericyst hyalinization, inflammatory cells in the cyst wall, cyst wall necrosis, calcification of cyst wall, degeneration of laminated membrane, severe degeneration or absence of germinal membrane, and inflammatory cells and necrotic material in the cyst cavity. CONCLUSIONS: Percutaneous treatment of hydatid disease was effective in the animal model. Ultrasound was useful in evaluating the intervention.

Animals↗
PubMed1993

Effect of povidone-iodine lavage on peritoneal defence mechanisms in rats.

OBJECTIVE: To assess the effect of povidone iodine lavage on peritoneal defence mechanisms in rats. DESIGN: Randomised study. MATERIAL: 90 Wistar albino rats. INTERVENTION: Rats were divided in three groups of 30. All rats underwent midline laparotomy, and 20 rats in each group had peritoneal lavage with 20 ml 1% povidone iodine, samples being taken before lavage in 10 and after lavage in 10. MAIN OUTCOME MEASURES: Effect of povidone-iodine lavage compared with laparotomy alone on bactericidal activity of peritoneal fluid (group 1); chemotactic indices of polymorphonuclear leucocytes (PMNL) (group 2); and total cell counts, cell types, and peritoneal phagocytic activity (group 3). RESULTS: Lavage with povidone-iodine increased the total peritoneal cell count/washing from 10.4 x 10(6) to 12.4 x 10(6) (p < 0.005), peritoneal bactericidal activity from 69.2% to 92.7% (p < 0.05), and peritoneal phagocytic activity from 58.9% to 73.7% (p < 0.05) at the end of four hours. Chemotactic indices of peritoneal PMNL before and after lavage were 1.90 and 1.89, respectively. Among the cells in the peritoneal fluid, the proportion of PMNL increased, whereas those of macrophages, lymphocytes, and mast cells decreased (p < 0.005). CONCLUSIONS: These results differ from those that we found previously after saline lavage. Lavage with 1% povidone-iodine does not increase the detrimental effect of saline lavage; on the contrary, it may even enhance peritoneal defence mechanisms. Any detrimental effects of povidone-iodine lavage should be attributed to systemic rather than local toxicity.

Animals↗
PubMed1993

Neutropenic enterocolitis in patients without leukemia.

BACKGROUND: Neutropenic enterocolitis is a serious complication involving the bowel in patients with severe neutropenia. Most of the patients are undergoing chemotherapy for acute leukemia. METHODS: This is a report of three cases of nonleukemic neutropenic enterocolitis. In these cases neutropenia was caused by an analgesic (dipyrone), chemotherapy for multiple myeloma, and chemotherapy for lung carcinoma. Two patients were treated by surgery, one medically. RESULTS: The patient with multiple myeloma who was treated by exteriorization of the sigmoid colon died on the tenth postoperative day of multiple organ failure caused by sepsis. The other two patients survived. CONCLUSIONS: A review of the literature revealed 14 other patients without leukemia who had neutropenic enterocolitis. The cause, diagnosis, and possible treatment options of this entity are discussed.

Adolescent↗
PubMedDate not supplied

The effect of peritoneal lavage on peritoneal cellular defense mechanisms.

To assess the effect of peritoneal lavage on peritoneal cellular defense mechanisms, peritoneal fluid total cell counts, cell types, phagocytic activity and polymorphonuclear leukocytes (PMNL) chemotaxis before and 4 hours after saline lavage was studied on 70 rats. Lavage with 10 ml saline decreased the peritoneal total cell counts of rats from 10.6 x 10(6) to 6.6 x 10(6) (p < 0.005). Among the peritoneal cells, the fraction of PMNL increased whereas the macrophages, lymphocytes and mast cells decreased (p < 0.005). The phagocytic activity of peritoneal phagocytic cells did not change significantly by peritoneal lavage. However, after lavage, PMNL instead of macrophages were the prominent phagocytic cells. Chemotactic index of peritoneal PMNL also did not change with saline lavage. It is concluded that although the phagocytic and chemotactic activity of peritoneal fluid cells are not affected by peritoneal lavage, cellular defense of the peritoneum may be compromised by altering the total cell counts and their composition.

Animals↗