Biomedical subjects

O Alexa

Publications and source records attributed to O Alexa.

15 recordsLinked to original sources

PubMedDate not supplied

[The effects of different types of pulsed electromagnetic fields on fibroblast cell cultures].

UNLABELLED: The aim of this study is to determine which is the most effective pulsed electromagnetic field (PEMF) on a fibroblastic culture cells. MATERIAL AND METHODS: Five different types of PEMF are generated by a pulsed generator created by the author. The electric signal, received by a reference coil is pulse bursts type. The growth rate of a fibroblastic culture cells is measured with and without different types of PEMF. RESULTS: Comparative results showed the the most effective type of PEMF is characterized by a 15 mV positive amplitude of the signal and a 15 Hz frequency of the bursts. The intermittent stimulation (8 hours/day) was more effective than continuous stimulation.

Cells, Cultured↗

PubMedDate not supplied

[Treatment results in aseptic necrosis of the femur head].

Between 1.01.1987 and 31.12.1997, 40 patients (52 hips) were diagnosed with avascular necrosis of the femoral head (ANFH) and treated in the Emergencies Hospital of Iaşi. ANFH was detected by clinical findings, plain radiographs and computed tomographic scans. We used the classification of Ficat and Arlet and the choice of treatment between core decompression (20 hips), flexion osteotomy (10), rotation osteotomy (4) or total hip arthroplasty (18) was determined by the stage and location of the area of necrosis. Core decompression has been attempted in patients with Ficat stages I and II, trochanteric osteotomy has been used in Ficat stages II and III, and in the most advanced stages of necrosis (Ficat stage III and stage IV) total hip arthroplasty was the procedure of choice. We reviewed the patients at 3, 6 and 12 months after the surgery. The results were evaluated using Merle D'Aubigne score. We noted good and very good results in 75% of our patients which were diagnosed in the early stages of necrosis. We concluded that the earlier diagnostic and the correct indication of treatment (determined by the stage of necrosis) are the premise for the amelioration of the severe prognostic of ANFH.

Adult↗

PubMedDate not supplied

Ender nailing versus external fixation in the stabilization of type III open tibial shaft fractures.

UNLABELLED: Management of severe open tibial shaft fractures presents a difficult challenge to the orthopaedic surgeon. They are frequently associated with loss of limb, infection and high levels of morbidity. All the authors considered, now, that there are five keys to successful treatment: antibiotic therapy, radical debridement and pulsed lavage irrigation, stabilization of fracture with minimal further devascularization, early soft tissue coverage and early bone-grafting. It rests, also, a number of controversies in the management of open tibial fractures, not least of which is the method of fracture stabilization: the choice between intramedullary nailing and external skeletal fixation, the use of reamed or unreamed nails. MATERIAL AND METHODS: Fifty-seven patients with 62 open fractures of the tibial shaft type IIIA, B and C (Gustilo) were treated between 1.01.1994 and 31.12.1998 in the Department of Orthopaedic Surgery of the Emergency Hospital, Iasi, Romania. There were 29 cases type IIIA fractures, 26 cases type IIIB and 7 cases type IIIC (Mess score showed the viability of the limb). Our patients were 36 males and 21 females; their mean age was 36 years (range 17 to 70). Forty-six patients were injured in road traffic accidents and 11 in other traumatic incidents. In 33 cases the skeletal stabilization was achieved by Ender nailing under general or regional anesthesia. In 15 cases we used a bilateral uniplanar external fixator (Burghele) and 14 fractures were stabilized with an Ilizarov external fixator. We note a secondary amputation after the failure of the revascularization of the limb in a type IIIC fracture. RESULTS: All fractures united; the mean time to union was 30.2 weeks--in the external fixation group and 26.4 weeks--in the Ender nailing group. Malunions occurred slightly more frequently in the external fixation group that in the Ender nailing group (15.7% versus 5.8%). We noted--also--more secondary procedures required in the external fixation group. The infection rate was 3 of 33 (9.1%) in the Ender nailing group compared to 4 deep (13.8%) and 8 pin-tract infection (27.6%) in the external fixation group. CONCLUSIONS: Our study suggests that Ender nailing has several advantages over external fixation in the management of severe open tibial shafts fractures. Based on these results, over the last years, in our Department we use mainly the Ender nailing technique, as we consider it a better approach for these type of lesions.

Adolescent↗

PubMedDate not supplied

[The relationship between benign breast proliferation (fibrocystic mastopathy) and the appearance of breast carcinoma].

Fibrocystic mastopathy (FM), a benign lesion, is considered by many author like a premalignant lesion. Breast carcinoma (CA) represents the most frequent female tumor and the second mortality cause through cancer, after the bronchopulmonary cancer. At the Department of Pathology from Tg. Mureş, we selected 190 cases, for 10 month: 102 presented FM, 41 CA and 47 CA + FM. In every case, we have examined 2 slides stained with HE. In difficult cases, we performed special stains (van Gieson, H-PAS, Alcian). We studied the pulmonary tumor, adjacent mammary tissue and axillary lymph nodes. The present data of literature and the experience of the Department of Pathology from Tg. Mureş showed a strong relationship between the presence of FM and the appearance of CA: both lesions have a common field of hormonal disfunction and intraductal and intralobular hyperplasia (an microscopic feature of mastopathy) increase the risk of CA.

Adolescent↗

PubMedDate not supplied

[Radiological findings in distal radius fractures].

X-ray examination in distal radius fractures is very important for the management and prognostic of these fractures. Anterior and lateral radiographs must be taken in standardised position to avoid errors in measurements. On antero-posterior x-ray of the distal radius the important parameters are: radial length (N = 11-12 mm), radial angle (N = 22 degrees-25 degrees) and radial width. For the radial length three methods of measurements (Gartland, Gelberman and Palmer) are presented. On the lateral x-ray the palmar inclination of the distal radius may be measured (N = 10 degrees-12 degrees). Modifications of these parameters associated with distal radius fractures are presented.

Humans↗

PubMedDate not supplied

[Displaced femoral neck fractures: internal fixation or arthroplasty?].

Femoral neck fractures are a challenge for orthopedic surgeon due to the high rate of complication for such fractures. The aim of this study was to propose a treatment algorithm based on author's current concept in management of femoral neck fractures. Fractures were classified according Garden in four types but, for practical reasons, fractures were considered undisplaced (Garden I and II) and displaced (Garden III and IV). Treatment method was chosen based on next criteria: patient's age, associated pathology, patient's mental status and expectations, quality of the bone (osteoporosis), type and age of fracture, quality of reduction. Based on this criteria, the proposal algorithm may led to close reduction and internal fixation, open reduction and internal fixation or arthroplasty.

Aged↗

PubMedDate not supplied

[Compression hip screw in trochanteric fractures. Conclusions based on 128 cases].

Compression hip screw is currently used in our department since 1998 and we operated 128 trochanteric fractures using DHS (Synthes) or Omega system (Howmedica-Stryker). We recommend the use of this implant in all stable fractures, most unstable fractures and we believe it is useless in reverse oblique trochanteric fractures. Best time for surgery seems to be the first or second day after admission. A preoperative planning must precede the surgery. We prefer the lateral approach of the hip with "L" type incision for vastus lateralis. For insertion of implant AO original technique was used. Mechanical complication occur only in unstable fractures but the failure rate was lower than for other implants. Patient with stable fractures were allowed full weight bearing immediately postoperative, this being delayed 6 weeks for patients with unstable fractures. We recommend compression hip screw as a very useful implant in trochanteric fractures.

Biomechanical Phenomena↗

PubMedDate not supplied

[A population study on the possible involvement of trace minerals in water in cardiovascular diseases].

Starting from the hypothesis of a possible protection exerted by oligominerals in cardiovascular diseases, 660 water sources were analysed as to their content in mineral matter. It resulted that the population drinks a very hard water with a low content in zinc, manganese, copper and chromium oligominerals. By correlating these characteristics with the mortality rate by cardiovascular diseases, low in the territory under study, it became evident that no association between these factors can be made, the relative protection being probably due to other factors.

Adult↗

PubMedDate not supplied

[Dynamic condylar screw in reverse oblique trochanteric fractures].

The aim of the study was to evaluate the results of internal fixation with Dynamic Condylar Screw (DCS) in reverse oblique trochanteric fractures. In a two years period 238 patients with trochanteric fractures were treated in our department. In 31 cases (13%) the fracture has reverse obliquity (type II Evans). Internal fixation was performed with Ender nails (4 cases), AO condylar blade plate (11 cases), Dynamic Hip Screw (3 cases), Gamma nail (3 cases) and DCS (10 cases). Results 4 month after the surgery reveal that Gamma nail and DCS used in reverse oblique fractures were superior to other types of implants. Placement of DCS may be difficult in fractures with large displacement and technical solution in such fractures are presented. In conclusion we consider that, in type II Evans trochanteric fractures, internal fixation with DCS is a good option.

Aged↗

PubMedDate not supplied

[Compression hip screw fixation with bone cement in trochanteric fractures].

Internal fixation with compression hip screw (DHS) of trochanteric fractures in osteoporotic patients may be followed by failure of fixation. The most common failure is represented by the "cut-out" of the screw. This complication may occur in 4-10% of unstable trochanteric fractures. In order to avoid such a problem we chose a technical solution that offers a good fixation of the screw in the femoral head. The technique, described by Bartucci, was used in a 78 years old female with unstable trochanteric fracture and severe osteoporosis. The postoperative result was very good and no mechanical complications were noted. We consider that the technique of augmentation of fixation using acrylic bone cement may be a solution in such cases.

Aged↗

PubMedDate not supplied

[Dewar-Barrington technique original adaptation used in the treatment of acromioclavicular dislocations].

The authors are presenting a method of treatment of acromioclavicular dislocations using the Dewar-Barrington technique modified in an original manner. The originality of the technique consists in the supplementary fixation of the tip of the coracoid process using a "figure-of-eight" loop of wire, placed around the head and the prominent tip of the screw. The advantages due to this modification of the technique are: avoiding of technical difficulties, the absence of complications which could appear after the original Dewar-Barrington procedure, the shorter immobilization period and the earlier beginning of full range of motion of the shoulder.

Acromioclavicular Joint↗

PubMedDate not supplied

[Stress fracture of the internal sesamoid bone of the first metatarsophalangeal joint. Case report].

We present the case of a fourty-two year old truck driver without a major trauma history who was diagnosed in our unit as having a stress fracture of the first metatarsophalangeal joint medial sesamoid bone. Conservative treatment consisting of 30 day immobilisation was our treatment choice. The result was very good and at six month follow-up the patient had no complains. We have searched for other opinions but there is a paucity of published literature on the injuries of the lesser toe sesamoids of the foot. The literature review revealed different types of treatment such as: conservative treatment, internal fixation of the sesamoid fracture (screw fixation), reduction of weight-bearing pressure on the affected sesamoid, ice massage or sesamoidectomy. Due to the fact that the different conclusions are based on very few cases, it is no possible to conclude about optimal treatment.

Adult↗

PubMedDate not supplied

[The characteristics of medical health care at the level of the rural medical dispensary in Iaşi County].

Attributes of health care in a rural health center from Iaşi (57.20%) and preventive actions (42.80%), with an average annual medical care of 1.15 days/person. Given the increased number of elderly in the respective area, the degenerative diseases (cardiovascular, rheumatic, chronic respiratory) are prevalent. Prevention mainly consists of vaccinations (26%).

Adolescent↗

PubMedDate not supplied

[Therapeutic management in trochanteric fractures].

The authors present the management of trochanteric fractures based on 343 fractures treated in Department of Orthopaedics and Trauma in Clinical Hospital of Emergencies of Iaşi for 5 years. The non-operative treatment was used in 17.2% of cases and the conservative methods were plaster immobilization, continuous traction and early mobilization. The surgical treatment was used in 82.8% of cases. The reduction of the fractures was usually possible using closed methods. For fixation, the authors used four types of implants: the 135 degrees blade-plate in 9.2% of cases, the condylar blade plate in 44.7%, Ender nails in 45.4% and DHS in 0.6% of cases. The choice of one of this methods depends on the type of fracture, age of the patient and on his biological status.

Adolescent↗

PubMedDate not supplied

[Electrically induced osteogenesis. II. Experimental studies].

The paper presents the possibilities to induce osteogenesis using different types of electrical current. The direct current may be used with invasive or semi-invasive methods. Electrodes are placed internally, near the bone. Experiments showed that the optimum stimulation is achieved with current between 5 and 20 microamperes. The capacitive current is able to induce osteogenesis. The electrodes are placed externally; between the electrodes there is an electric field with the value ranged 1-10 millivolts/cm. The method of pulsed electromagnetic fields is based on the field produced by a coil placed externally. The magnetic field range between 0, 1 and 20 gauss. This is the most appreciate method because is noninvasive and offered the best experimental results.

Animals↗