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Biomedical subjects

O Anders

Publications and source records attributed to O Anders.

36 records · Page 2Linked to original sources
PubMed1984

[Serum iron and serum copper in patients with lymphogranulomatosis].

The serum iron and serum copper level was determined in fifteen patients with lymphogranulomatosis before and during the course of the therapy. While the serum copper was increased in all stages, for the serum iron only in the stages III and IV a tendency to diminution was found. With obtaining the remission a significant increase of the serum iron and a significant decrease of the serum copper developed. The normalization of serum iron and serum copper suggests a remission, the dissociation of the two parameters an activity of the lymphogranulomatosis.

Adolescent↗
PubMed1984

[Electrophoretic study of lymphocytes from a patient with hairy cell leukemia].

The electrophoretic mobility of lymphocytes is identified in the peripheral blood and from the spleen taken from a patient with hairy cell leukemia. Lymphocytes reveal an unimodal distribution with a low mobility in the histogram. There are no differences between the results obtained by investigating the peripheral blood and those of the spleen. Hairy cells could be delimited from lymphocytes of chronic lymphatic leukemia and immunocytoma by determining EPM.

Adult↗
PubMed1984

[Therapy of calculus-induced hematuria in hemophilia A].

In a patient with haemophilia A who had a staghorn calculus with recidive haematuria nephrectomy was performed without complications. The operation was preceded by compensation for the haemostasis deficiency by substitution of coagulation factor concentrates. Substitution therapy in connection with operations is discussed and obligatory surgical and haemostaseological preconditions are stated.

Hematuria↗
PubMed1984

Cell electrophoretic characterization of peripheral blood lymphocyte subpopulations enriched by rosette formation, from normal individuals and CLL patients.

Peripheral blood lymphocytes from healthy subjects and patients with chronic lymphatic leukemia (CLL) were isolated and their subpopulations enriched through formation of spontaneous rosettes with sheep or mouse red blood cells, respectively. Electrophoretic measurements were performed in unseparated as well as in fractionated cell populations. Normal blood lymphocytes showed two clearly distinguishable populations of different electrophoretic mobilities. After separation by SRBC rosette formation the rosette-forming cells could be identified as high mobility cells. CLL lymphocytes showed in most cases an unimodally distributed cytopherogram, the mean electrophoretic mobility being intermediate between the low and high mobility cells of control persons. After separation through mouse erythrocytes rosette formation these cells contained two cell fractions differing in their electrophoretic mobility: a fraction of slower mouse rosette-forming cells and a fraction of the non-MRFC which contained mainly cells of higher mobility that could be identified as enriched T cells. These both fractions showed unimodal distributions. This study shows that CLL lymphocyte subpopulations can be further characterized by surface charge density.

Animals↗
PubMed1983

[Diagnosis and therapy of primary extranodal non-Hodgkin's lymphoma of the stomach].

In the period from 1970-1980 120 patients with NHL were treated. A primary stomach manifestation could be detected in 6.6%. Problems of pre-operative, endoscopic-bioptic diagnostics are discussed and recommendations for a therapeutic proceeding are given. The tumour is surgically removed at stage I and II, which is always followed by polychemotherapy. Primary polychemotherapy is used at stages III and IV. Patients at stage II achieved a complete remission, those at stage IV died within 6 months after diagnosis.

Adult↗
PubMed1983

[Successful therapy of uncontrollable macrohematuria caused by the cyclophosphamide-injured bladder].

An uncontrollable bleeding of the urinary bladder was successfully treated using a 4% formalin strip tamponade with vesico-ureteral reflux and supportive therapy with thrombocyte concentrates and transfusions of fresh blood. Non-toxic side-effects of oxazaphosphorin derivates and modern methods of prophylaxis using a uroprotectic are presented. Previously the use of formalin together with vesicoureteral reflux was contraindicated; in this case it was successfully applied for the first time via the suprapubic route using a strip tamponade.

Adult↗
PubMed1982

[Gastroesophageal reflux and gastric secretion].

In 47 patients with reflux complaints and pH-metrically recognizable gastrooesophageal reflux (glass-calomel-electrode system) we succeeded in proving the fact that a large volume of gastric secretion and a lower intragastric pH-value are concomitant with a significant prolongation of the total reflux duration by increase of the reflux frequency.

Female↗
PubMed1982

[The primary malignant non-Hodgkin lymphoma of the stomach].

From 1970 to 1980, 643 patients suffering from a malignancy of the stomach were seen at the Surgical Department of Rostock University. 8 of them were identified to have a Non-Hodgkin lymphoma. Treatment should be done depending on the staging: Stage I and II extirpation of the tumour followed by adjunctive chemotherapy, Stage III and IV primary chemotherapy only.

Adult↗
PubMed1981

[Lymphogranulomatosis and heart involvement].

In the early extralymphatic affection of the organs without relevant clinical and roentgenological findings the diagnosis of the lymphogranulomatosis makes difficulties. It is referred to the peculiarities of the extra-nodal manifestation. The case of a lymphogranulomatosis with early participation of the heart is described and it is gone more fully into the differential diagnosis. Disturbances of the regression of excitation in the ECG are etiologically ambiguous and may be the first recognizable findings of a penetration of a tumour into the pericardium.

Adult↗
PubMed1981

[Reflux disease and sphincter pressure].

Between patients with reflux oesophagitis (n = 8), patients with symptoms of reflux without oesophagitis (n = 27) and controls (n = 17) recordings of lower oesophageal sphincter pressure have shown no significant differences of mean sphincter pressure but a significantly lower increase of mean sphincter pressure in patients with oesophagitis and/or symptoms of reflux after pentagastrin (6 microgram/Kg b.w., s.c.) by means of pull-through perfusionsmanometry. Nearly in half of the patients with oesophagitis and symptoms of reflux basal sphincter pressure and sphincter reaction on pentagastrin were found in a normal range. Disturbances of basal sphincter pressure and its reaction on pentagastrin have shown a dependence on the anamnesis duration.

Esophagitis, Peptic↗
PubMed1981

[The effect of neostigmine and atropine on gastro-oesophageal reflux (author's transl)].

During 6 hours continuous pH-measurements were undertaken to study the effect of neostigmine (0,5 mg s.c.) and atropine (0,5 mg s.c.) on gastro-oesophageal reflex after a standardised meal (n=18). Mean total reflux duration, single reflux duration and mean reflux frequency were not effected by neostigmine. Mean total reflux duration and mean reflux frequency were not effected by neostigmine. Mean total reflux duration and mean reflux frequency were reduced by atropine during the first hour p.i. (a less than 0,01).

Atropine↗
PubMedDate not supplied

Cell electrophoretic characterization of lymphoid cells from various sources in patients with malignant non-Hodgkin lymphomas.

Lymphocytes of 36 patients with malignant Non-Hodgkin lymphomas (NHL) were characterized by electrophoretic mobility (EPM) and EAC-rosette and E-rosette formation. Unimodal cytopherograms found in patients with low-grade malignant NHL are compatible with a monoclonal origin of the proliferating lymphoid cells. Within the CLL subgroup, deviations from the general mean EPM value in the intermediumrange were not unequivocally related to the B- or T-cell origin of the lymphocytes and remain to be explained. Comparing distinct entities of low-grade malignant NHL characterized by lymphocyte arrest at a certain stage of differentiation (Kiel Classification) we found an increase of the mean EPM in the direction of CLL----lymphoplasmacytoid immunocytoma----polymorphic immunocytoma. This arrest of leukemic cells at a certain EPM level may support a cytogenetically oriented subclassification of NHL. The Limitations of the diagnostic value of cytopherograms and rosette formation in malignant NHL--especially in those of high malignancy--are outlined.

Bone Marrow↗