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Biomedical subjects

O B Chentsova

Publications and source records attributed to O B Chentsova.

At least 19 recordsLinked to original sources
PubMed1986

[Radiation therapy of malignant eyelid tumors].

The authors presented the short- and long-term results of brachytherapy and combined radiotherapy in 348 patients with malignant eyelid neoplasms localized in the lower eyelid in 187 patients, in the upper eyelid in 99, in both eyelids in 4, in the inner angle of the eye in 39 and in the outer angle of the eye in 10 patients. A single focal dose was 1.5-2.5 Gy, a total dose 45-80 Gy with relation to tumor prevalence and histological structure. The eyeball was protected with the help of a lead lens ("eye prosthesis") and a universal tungsten membrane. The devices ensured nearly 100% protection of the eyelid against ionizing radiation. Direct clinical cure was noted in 342 patients, partial tumor resorption in 6 patients. Three-year recurrence-free survival was noted in 330 patients (94.8%), five-year survival in 319 (92.8%).

Adult↗
PubMedDate not supplied

[Clinical and immunological criteria for predicting the course of uveitis].

Clinical and immunological parameters are studied in 205 patients with uveites of different etiology in order to define the criteria permitting the prediction of uveitis course and relapses. The prognosis is unfavorable for autoimmune conditions, including peripheral, systemic, syndromal, tuberculous uveites and mixed infections. Clinical cure is unstable in diffuse inflammatory changes, persistent cellular infiltration of the vitreous body, formation of cyclic membranes in it, in cataract complications, and exudative hemorrhagic chorioretinitis. High titers of antibodies to tissue antigens and deficiency or hyperimmunoglobulinemia A, discoordination of T and B immunity, and sensitization to several antigens are risk factors for relapses. Clinical and immunological parameters should be analyzed for predicting the disease course and prescribing the basic and antirelapse therapy.

Autoantibodies↗
PubMedDate not supplied

[Comparative analysis of the efficacy of some methods of conservative treatment of accomodation spasms and myopia in children].

A study was carried out of short- and long-term results in treatment of accommodation spasms and myopia of mild and moderate degrees in children with equipment having different operating mechanism. 171 patients aged 6-15 years were examined (30 persons made up a control group). Electrostimulation, laser stimulation and treatment on "Ambliokor" equipment were used. It was found out that these procedures give a good immediate effect in treatment of accommodation spasm and myopia but 5-6 months later the obtained results deteriorated in 2/3 of children and therefore it is recommended to repeat the treatment in the above period. Using "Ambliokor" equipment provides the best short-term effect. The highest effectiveness of treatment was obtained in combined method comprising all three procedures which made it possible to reduce the rate of myopia progression 2-fold and more compared with the similar index in the control group.

Accommodation, Ocular↗
PubMedDate not supplied

[New clinical forms and diagnosis of ophthalmic chlamydiosis].

The paper deals with new clinical forms of ophthalmoclamidiosis involving lesions to the choroids, retina, optic nerve and cornea. Uveitis and scleritis were found in 73.5% and 26.5%, respectively. Iridocyclitis and paneveitis prevailed in cases of uveitis. Forty-two patients, aged 3 to 53, were followed up. Bilateral ocular lesions were registered in 67% of them. The progression, clinical course and outcomes of the disease were investigated by using the up-to-date laboratory-and-immunologic methods. Direct immunofluorescence and polymerase chain reaction, when used alongside with serological examinations, were found to be most informative. A combination of ophthalmoclamidiosis with urogenital pathologies was registered in 76% of patients.

Adolescent↗
PubMedDate not supplied

[Organizational aspect of medical care rendered to children with abnormal refraction under the conditions of school education].

The main purpose of the case study was to investigate the efficiency of different-method treatment of children with abnormal refraction. One hundred and fifty children were examined and shared between 3 experimental and one control groups. Routine ophthalmic examination methods were made use of; they are: visometry, autorefractometry, ophthalmobiometry, determination of the scope of relative accommodation, biomicroscopy, ophthalmoscopy; additional examinations, like rheoencephalography and consultation by neurologist, were also used. It was for the first time that the efficiency of infrared pneumomassage and of color-pulse therapy in the treatment of abnormal refraction was dynamically studied under the conditions of school education (vision correction rooms). The amplitude of relative accommodation increased in 71.6% of cases and the acuity of vision--in 78.8% of cases after the main treatment course; the refraction stabilized in 25-30% of cases. The results declined in 25-30% of cases after 3-4 months, therefore, treatment courses need to be repeated 3 times per year. Besides, positive results were obtained in the treatment of abnormal refraction by punctate massage of biologically active points, by general exercise and exercise for eyes as well as by massage of the collar zone and by medicamental therapy. Indications and contraindications were defined for the complex treatment of accommodation cramp and of abnormal refraction.

Adolescent↗
PubMedDate not supplied

[Low-intensity helium-neon laser irradiation in multimodal treatment of corneal injuries].

He-Ne laser stimulation was used in multiple-modality treatment of 512 patients with various corneal conditions: 217 with perforating wounds, 75 with chemical and thermal burns, 48 with ulcers of various origins, and 162 with endothelial-epithelial dystrophy resulting from cataract extraction with implantation of the intraocular lens. A course of treatment consisted of 6 to 10 daily 3 min exposures at radiation power density of 50-100 micro W/cm2 on the cornea. The effect achieved by laser stimulation was significantly superior to that of routine methods of treatment used in the reference groups. He-Ne laser stimulation was conducive to a sooner reduction of the inflammatory processes, to recovery of the corneal sensitivity and epithelialization, and to shortening hospital treatment.

Burns, Chemical↗
PubMedDate not supplied

[Immuno-correcting therapy of sympathetic ophthalmia].

Exchange plasmapheresis was used in correction of the immune homeostasis in 5 patients with sympathetic ophthalmia. The inflammatory process ceased in all the cases. Exchange plasmapheresis resulted in improvement of the blood supply to ocular vessels, of intraocular vessel function, and of metabolic processes in the external layers of the retina. Cellular and humoral immunity parameters normalized. The hemo- and hydrodynamic parameters of the eye improved; all these results evidence that exchange plasmapheresis is an effective method in the treatment of sympathetic ophthalmia.

Adult↗
PubMedDate not supplied

[A crystallographic method of examining the lacrimal fluid in the diagnosis of various eye diseases].

The authors analyze the results of examinations of the lacrimal fluid by the crystallographic method in 123 patients with inflammatory, dystrophic, and tumor diseases of the eyes and orbit and in 20 healthy controls. The examinations have revealed essential changes in the lacrimal fluid crystallograms of normal subjects and patients with various ocular and orbital diseases, which fact recommends this method as one of the tools for the differential diagnosis of diseases of the organ of vision.

Adolescent↗
PubMedDate not supplied

[Exchange plasmapheresis in combined treatment of severe uveitis].

Exchange plasmapheresis (EP) has been employed in multiple-modality therapy of 15 patients suffering from severe uveitis. The traditional therapy has yielded but a short-term effect and failed to stabilize the process in these patients. EP has resulted in improvement in all the patients: the injection has reduced, as well as the number of precipitates and oracities in the vitreous body; hemorrhages in the fundus oculi have resolved, and the vision acuity has considerably improved in 11 of the 15 patients; no cases of the deterioration of the vision acuity have been recorded. The relapses have ceased in 10 patients. EP has been well tolerated and yielded no complications; it has normalized the levels of the blood serum immunoglobulins and circulating immune complexes and activized phagocytosis.

Adult↗