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O B Emery

Publications and source records attributed to O B Emery.

7 recordsLinked to original sources
PubMed1991

Serotonin uptake in the blood platelets of Alzheimer's disease patients.

We determined serotonin (5-HT) uptake in the blood platelets of Alzheimer's disease (AD) patients and comparable age-matched normal controls. The maximum number of 5-HT uptake sites (Vmax) was significantly increased in mild and moderate AD patients, and a trend toward decreased V max was observed in severe AD patients as compared with normal controls. The Km of 5-HT uptake was negatively correlated with the Face-Hand Test (FHT) score of severely ill AD patients, whereas Vmax was correlated with the FHT score and the Mental Status Questionnaire score in the entire AD sample.

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PubMed1989

Language deficits in depression: comparisons with SDAT and normal aging.

In order to contribute to the definition of the structure of cognitive deficits in major depression/unipolar, language processing was studied in 20 elderly persons with major depression/unipolar, 23 elderly with SDAT, and 20 normal elderly. Measures administered included the Western Aphasia Battery, Test for Syntactic Complexity, and Chomsky Test of Syntax. Results indicate that depressed elderly performance on structural language variables of repetition, naming, auditory verbal comprehension, syntax, and reading is significantly better than performance of the SDAT sample. In contrast, results suggest that in comparing normal and depressed elderly, the normal elderly have the edge. On three measures of eleven, there are significant differences between depressed and normal elderly language processing. In analyzing the measures of significant difference, it is determined that complexity is an intervening variable. It is concluded that although the reason for language deficits in major depression/unipolar is as yet unknown, it is not justifiable at present to rule out an organic hypothesis.

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PubMed1989

Long-term follow-up of depressive pseudodementia of the aged.

Forty-four elderly patients of both sexes (mean age 76.5 years) suffering from depressive pseudodementia were intensively treated for the depression. When that cleared up, cognitive function reverted to premorbid level. Patients were regularly interviewed and retested at six months intervals for four to 18 years (average 8). Some patients experienced, during the follow-up period, a recurrence of the depression for which they were again successfully treated. At the end of the observation period, 39 of the 44 patients (89%) had developed a dementia syndrome of the Alzheimer type.

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PubMed1988

The problem of naming in SDAT: a relative deficit.

Research relating to language disorder in senile dementia of the Alzheimer type (SDAT) has focused primarily on naming impairment, formally termed anomia or nominal aphasia/dysphasia. Data resulting from this research have been insufficiently informed by a comparative linguistic framework in which performance on naming tasks is contrasted with performance on other forms of language tasks. The present study involves the comparison of 21 adults with SDAT and 18 demographically controlled normal elderly adults on the Test for Syntactic Complexity and fifteen subtests of the Western Aphasia Battery. Performance on naming is compared with performance on oral language variables of repetition, yes/no response, auditory word recognition, sequential commands, syntactic processing, as well as with performance on reading tasks and non-verbal tasks. Findings relating to oral language tasks show that structured syntactic processing requiring explicit interpretation and sequential commands are significantly more difficult for the SDAT sample than are three of four naming tasks. Further, significant SDAT performance variability is found across naming tasks. The generative categorical naming task is found to be significantly more difficult for the SDAT patient than are the other three naming tasks. It is concluded that the generative categorical naming task should be regarded as a meta-naming task. In sum, it is found that although language dysfunction in SDAT has anomic components, the essential character of the language disorder is not best conceptualized as a problem of naming.

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PubMed1985

The defense process in posttraumatic stress disorders.

The authors discuss the role of the subjective determinants in the premorbid personality and in the symptom-formation of patients who develop posttraumatic stress disorders. Such factors are assessed through a careful evaluation of the defense mechanisms. It is suggested that psychotherapists focus their attention on the dynamics of such mechanisms and shape their interventions accordingly.

Adaptation, Psychological↗