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Biomedical subjects

O B Milenin

Publications and source records attributed to O B Milenin.

13 recordsLinked to original sources
PubMed1991

[Echographic evaluation of the structure and size of the kidneys in healthy newborn infants in the first week of life].

Echographic assessment of the renal structure and size was carried out in 39 healthy full-term babies during the first five days of their lives. Renal echograms of the examined newborns were characterized by highly echogenic cortical layer, ++hypo-echogenic central sinus, and unechogenic pyramids well imaged against the background of the cortical layer. A drastic increase of the echogenicity of some pyramids (3-5) was seen in 4 newborns on days 2-3 of life, not involving impairments of renal function. No differences in the sizes of the left and right kidneys, kidneys in boys and girls, or kidneys in various days of life were detected. To compare renal size of the newborns with other anthropometric parameters, renal volume should be correlated to body surface size. The data on renal size in healthy newborns may be used as reference values for newborns of the first week of life.

Age Factors↗
PubMed1990

[Disorders of hemodynamics in the acute period of respiratory distress syndrome (Doppler echocardiography)].

An all-round study of the cardiovascular system in 90 neonates with respiratory distress using Doppler's echocardiography has revealed 5 varieties of hemodynamic disorders: hypovolemia, transitory dysfunction of the left and right ventricle myocardium, persistent pulmonary hypertension, functioning arterial canal. Each of the enumerated varieties of circulatory disorders manifested itself by the characteristic symptom complex. However, frequent combinations of the disorders with each other made the clinical diagnosis fairly difficult. Doppler's echocardiography permitted one to make noninvasive diagnosis and to appraise the gravity of circulatory disorders.

Echocardiography↗
PubMedDate not supplied

[A method of decreasing accidental positive exhalation pressure upon high frequency artificial respiration of newborn infants].

A simple method has been suggested for the reduction of excessive positive end-expiratory pressure (EPEEP) occurring during high-frequency ventilation with positive pressure in the newborn. The method employs a special conntecor with an inner diameter decreasing towards the end of the tube included into the inspiration line. The use of a connector during high-frequency jet ventilation of lung models from newborn with hyaline membrane disease and meconial aspiration reduced effectively EPEEP in the proximal end of the intubation tube. However, the same efficacy of EPEEP reduction in the lungs has been observed only on the model of hyaline membranes. On the models of lungs from newborn with meconial aspiration EPEEP reduced insignificantly. With the increase in gas mixture flow, the efficacy of the device enhanced.

Humans↗
PubMedDate not supplied

[A method of reinfusing ultraviolet-irradiated autoblood in combined modality intensive therapy of pyo-inflammatory diseases in premature infants].

The method of UV-irradiated autoblood reinfusion was used in intensive care of 25 premature babies with pyoinflammatory diseases. On the second day after reinfusion 17 babies showed an improvement of infectious intoxication, decreased level of antigenemia, liquor purification, leukocyte blood count normalization and decreased levels of total bilirubin, residual nitrogen and urea. Within 5 days after the reinfusion the activation of antioxidant blood system and reparative processes was observed. No complications were noted. The effect was not achieved in 8 babies, 6 of which died.

Blood↗
PubMedDate not supplied

[Systemic and pulmonary hemodynamics in the course of substitute therapy with exosurf neonatal in newborn infants with respiratory distress syndrome].

The effect of double endotracheal administration of Exosurf Neonatal (Wellcome, Great Britain) in a dose of 5 ml/kg on the central and pulmonary hemodynamics, frequency of hemodynamically significant functioning arterial duct (FAD), and lung hemorrhages was studied by Doppler echocardiography in 25 newborns with the respiratory distress syndrome. The hemodynamic parameters were assessed before drug administration, directly and 2 hours after it, and at the age of 1, 2, and 3 days. An unreliable reduction of pulmonary vascular resistance and increase of volumic pulmonary blood flow were observed as soon as during the first minutes after administration of exosurf; this was not paralleled by a pathological increase of the left-right shunting of the blood through patent ductus arteriosus. During the three days that followed the postloading of the right ventricle reliably decreased and the pulmonary bloodflow, cardiac output, and systemic arterial pressure increased. If the traditional measures preventing the possible volumic overloading of the pulmonary circulation in the presence of patent ductus arteriosus were not neglected, administration of exosurf to newborns with the respiratory distress syndrome did not lead to an increase in the frequency of hemodynamically significant FAD and pulmonary hemorrhages.

Adult↗
PubMedDate not supplied

[New potentials for monitoring the temperature and the relative and absolute humidity of the air-oxygen mixture during the prolonged artificial ventilation of newborn infants].

A new HTM-902 monitor (UCCP, Germany/Serviceinstrument, Russia) was used for continuous measurements of the temperature and relative and absolute humidity of inspired gas during prolonged mechanical ventilation in 86 neonates with respiratory failure caused by the respiratory distress syndrome (n = 42), meconium aspiration syndrome (n = 28), and congenital pneumonia (n = 16). All measurements were performed with a special probe connected to the inspiratory contour through a standard adapter close to the patient's T-piece. The monitor helped maintain the optimal values of the inspired gas conditioning during assisted ventilation of the neonates. The optimal relationships between gas temperature and humidity can be attained only with humidifiers with a servocontrol of temperature and heated wire inside the inspiratory circle tube. For maintaining adequate humidity of inspired gas after any changes in the ventilator flow rate or in the temperature inside the incubator, the heating power of the humidifier had to be corrected. However, even with servocontrolled humidifiers and humidity regulation, an increase of temperature inside the incubator over 35 degrees C made impossible the maintenance of the inspired gas humidity at the level of 96-100% with its temperature at the level of the patient's T-piece no higher than 37 degrees C.

Air↗