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Biomedical subjects

O B Nechaeva

Publications and source records attributed to O B Nechaeva.

34 records · Page 2Linked to original sources

[Characteristics of clinical course of pulmonary tuberculosis in penitentiary population].

The course of consumption was studied in 374 residents of the Sverdlovsk Region who had been in prison for different periods of time. Among them, there were prevalent young males with lower educational and professional levels, who were single or divorced, and had a poor social status. A third of the patients had fallen ill mainly in the first 5 years of imprisonment. The disease was detected in the half of the remaining persons in the first 3 years after imprisonment. Despite frequent cases with severe tuberculosis, long-term multimodality therapy allowed the tuberculosis process to be adequately treated and the disease to be cured in most patients. The main cause that aggravates the course of tuberculosis is the patients' refusal to take a systematic treatment.

Adolescent↗

[Pulmonary tuberculosis in prisoners in corrective work institutions].

Respiratory tuberculosis course was followed up in 374 prisoners. They were all citizens of the Sverdlovsk region, for the most part males with a poor educational, occupational and social status. One third of the prisoners got infected within 1-5 years of their term. In half of the rest subjects the disease was detected within years 1-3 after the release. In spite of frequent cases of severe infection, persistent combined therapy led to the patients cure in most of the patients. The rejection of systematic treatment often aggravated respiratory tuberculosis course.

Adult↗

[Problems in the evaluation of predisposing factors to pulmonary tuberculosis].

Genetic predisposition is an important factor in pulmonary tuberculosis. The pattern of dermatoglyphic indicators is thought a reliable marker of such predisposition. Selective character of the disease emergence is related with an unfavorable combination of genetic and extra-genetic risk factors in an individual. A comprehensive assessment of the above factors may contribute to a reliable prediction of a high risk to develop tuberculosis.

Age Factors↗

[Tuberculosis in prisoners and persons released from penitentiary-labor establishments].

High tuberculosis prevalence found among the convicts of penitentiary-labour establishments 20 times exceeds that found among the adult population of the Sverdlovsk region. Constant migration of patients exists between the antituberculosis institutions of the region and penitentiary-labour establishments located on its territory. Considering the fact that adequate treatment of patients with antisocial behaviour cannot be organized in tuberculosis hospitals the problem must be solved at places of confinement.

Adolescent↗

[Causes of death of tuberculosis patients in the first year after diagnosis].

Causes of late diagnosis of respiratory tuberculosis were studied in 137 adult patients who died within a one-year follow-up in the antituberculosis dispensaries of the region; when the diagnosis was established as a cause of death, autopsies were examined. Among those who died of tuberculosis were mostly subjects aged over 50 years. They were not employed in industry and not been fluorographically examined for more than 2 years. The main causes to late tuberculosis diagnosis in patients who were regularly examined included medical errors and patients' disregard of their own health.

Adolescent↗

[Clinical course of lung cancer in workers exposed to industrial dust].

Studies of the clinical courses of lung cancer in 66 patients professionally engaged in dust-affected labour conditions in comparison with 219 diseased inhabitants of machine-producing industrial zones, revealed that the pneumoconiosis-related cases developed mostly peripheral forms of lung cancer. In pneumoconiosis-free patients occupationally engaged in labour conditions affected with dust, lung cancer, once it had appeared, was progressing very fast. This confirmed the necessity of annual preventive examinations of the workers who had been engaged in coniosohazardous labour conditions.

Adult↗

[THe experience of detecting lung cancer in an industrial district].

Clinico-roentgenological features of 191 patients with lung cancer at first presentation is discussed. Asymptomatic and inapperceptive cancer was registered in 52.6% of patients with peripheral tumor and in 15.7% with central cancer. Symptoms were underestimated in 18.8%. In 51.5% of case, lung pathology had already been evident on previous photoroentgenograms, but it had been either under- or misdiagnosed.

Adenocarcinoma↗

[Pulmonary tuberculosis as detected by different methods].

As a result of the study of clinico-roentgenologic pictures of 379 patients with newly-diagnosed pulmonary tuberculosis, asymptomatic and undetectable development of the disease was found in 64.2% of the cases with non-destructive and in 35.0% with destructive processes. Besides, clinical symptoms of 36.1% of the patients were neglected. The above situation proves it necessary to conduct preventive fluorographic examinations of the chest at least once every 2 years. Their quality should be significantly improved, as many patients had fluorographic changes on the prior examination, which were missed or misinterpreted. The organization of early tuberculosis detection cannot be judged from the proportion of destructive processes in the pattern of tuberculosis morbidity.

Adult↗

[Hereditary predisposition to oncological diseases in leukemia patients].

Study on the genealogy of 671 patients with hemoblastosis has evidenced a more frequent incidence of malignant neoplasms in the families of patients with chronic lympholeucosis, erythremia and lymphogranulomatosis compared with the families of practically healthy persons. Whereas this regularity is not revealed in the families of patients with acute forms of leucosis and chronic myeloleucosis.

Acute Disease↗