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Biomedical subjects

O Barrett

Publications and source records attributed to O Barrett.

At least 19 recordsLinked to original sources

Recurrent rhabdomyolysis in association with cocaine use.

As the popularity of cocaine increases in our society, so does the frequency and variety of medical complications associated with its use. A growing number of cases have implicated cocaine use in the development of rhabdomyolysis and its complication, acute renal failure. We have reported the first case of recurrent rhabdomyolysis and acute renal failure directly associated with cocaine use. Although adulterants might cause muscle damage, we believe cocaine should be added to the list of drugs that are capable of producing rhabdomyolysis.

Acute Kidney Injury↗

Electrocardiographic diagnosis of left atrial enlargement. Role of the P terminal force in lead V1.

The ability of the electrocardiographic criterion, P terminal force in lead V1 (PTF-V1), to diagnosis left atrial enlargement (LAE) is evaluated in a group of 317 men. A left atrial index greater than 2.2 cm/m2, determined by echocardiography, is used as the standard for LAE. The value for this criterion of 0.04 mm-sec performs best, although there is no significant difference in percent correct diagnosis for values of PTF-V1 ranging from 0.03 to 0.09 mm-sec.

Adult↗

Myocardial infarction in sickle cell anemia.

A review of the electrocardiograms (ECG) of 108 patients with sickle cell anemia found only 3 with patterns consistent with myocardial infarction. Two of the 3 patients with ECG infarct patterns had postmortem examination confirmation of the infarction. These two patients had no significant coronary atherosclerosis nor did the other six autopsied patients in the present series. Literature reports of postmortem examinations on patients with sickle cell anemia confirm the scarcity of coronary atherosclerosis and myocardial infarction in these patients. Forty of the 108 ECGs showed signs of left ventricular hypertrophy and 20 others had nondiagnostic ST and T wave abnormalities. Nine showed first degree AV block and four right bundle branch block.

Adult↗

Positive mono-spot test in histiocytic medullary reticulosis.

A case of rapidly fatal histiocytic medullary reticulosis in which two positive mono-spot tests were found is presented. In addition, there was a low liter antibody to EB virus. The patient died with a bleeding diathesis terminally. Postmortem examinations confirmed the diagnosis of histiocytic medullary reticulosis.

Adult↗