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Biomedical subjects

O Bartels

Publications and source records attributed to O Bartels.

At least 19 recordsLinked to original sources
PubMed1991

[Insulin injection aid. Experiences with its use in Type II diabetes patients].

This article reports on the experience gained with an insulin injection aid for use by type II diabetics. The baseline data provided by a questionnaire survey are discussed in detail. The "pen" proved simple to use and was readily accepted. A number of shortcomings were identified and improvements suggested. The significantly superior metabolic control observed in patients using such aids is briefly discussed. In addition, detailed consideration is given to the models presently available and desirable future prospects are identified.

Adolescent↗
PubMed1985

[Postpartum hemophilia A with factor VIII inhibitor].

An abnormal life-threatening haemorrhagic diathesis occurred 6 weeks after delivery in a 25-year-old female. The reason was a spontaneously acquired factor VIIIC inhibitor haemophilia. The clinical presentation was characterised by extensive deep-seated soft-tissue haemorrhages of the extremities, a retroperitoneal haemorrhage, haematuria and recurrent joint bleedings. The activity of factor VIIIC decreased to below 1% of normal. The factor VIII inhibitor reached a maximum of 122 Bethesda units. The recurrent knee joint haemorrhages responded well to treatment with an activated prothrombin complex concentrate (Feiba). Repeated Feiba administration did not lead to an increase of the factor VIII inhibitor. It disappeared completely within 16 months and did not recur during a second pregnancy. The pregnancy was without complications and delivery on time resulted in a healthy child. Six months after the second pregnancy both mother and child showed no evidence of a disorder of haemostasis.

Adult↗
PubMed1985

Pulmonary sarcoidosis associated with acquired humoral and cellular immunodeficiency.

A previously healthy 27-year-old man with class II pulmonary sarcoidosis developed severe humoral immunodeficiency within the course of the disease with an IgG of less than 250 mg/ml and undetectable levels of IgA and IgM. Repeated skin tests were negative for seven common recall antigens. Cellular blood test demonstrated normal numbers of B cells and slight T-cell lymphopenia with a normal T-helper/suppressor subset distribution (ratio 1.6). In contrast, parallel examination of the bronchial alveolar lavage fluid (BAL) demonstrated highly elevated numbers of T cells with a subset ratio of 3.1 and significant numbers of activated T cells as revealed by the expression of Ia and Tac antigens. Functional in vitro assays showed a greatly decreased mitogenic response of blood T cells and diminished production of immunoglobulins. These data indicate that, despite a severely depressed systemic humoral and cellular immune system, T-cell activation can take place at the inflammatory site, potentially causing the lesions characteristic of sarcoidosis.

Adult↗
PubMed1984

[Anorexia nervosa. A catamnestic analysis].

Over a period of 10 years 25 patients, 24 of them females, with anorexia nervosa were observed. The disease is characterized by marked loss of weight, amenorrhoea, low blood pressure and early-onset behavioural disorders towards members of the family and friends. Anaemia, peripheral oedema and pronounced muscular weakness due to electrolyte imbalance may be observed in advanced cases. The disease commences in puberty by more or less obvious loss of weight following reduced food intake, rarely it is caused by vomiting and laxative abuse. Patients tend to deny connections between reduced food intake and loss of weight. There is no standardized treatment. Therapy should be initiated by the psychiatrist. In severe cases parenteral nutrition and intensive care may be required. This is particularly true in complicated cases such as occurrence of infection, serious electrolyte disorders or coagulation defects. The earlier a diagnosis is made the better the prognosis. Manifest disease of more than 5 years' duration decreases the chances for cure considerably.

Adolescent↗
PubMed1984

[Myelosarcoma--an unusual heart tumor. Differential diagnosis of hypertrophic and non-obstructive cardiomyopathy].

Heart tumours are seldom; secondary malignant tumours occur more often than primary heart tumours and there are no characteristic symptoms. According to the location and extent, tumours of the heart can cause practically all the known cardiological symptoms, not only in the discrete, but also in the dramatic form. Frequent symptoms are disrhythmia , myocardial insufficiency and pericardial effusion. In the case of uncertain cardial symptoms a possibly malignant heart disease should be looked for by means of ultrasonics, computer tomography, myocardszintigraphy and if necessary angiocardiography. If a diagnosis is made in time, the patient can be helped either by surgery, or in cases of secondary, malignant infiltrations the patient can often be treated successfully with chemotherapy or radiation. In cases of unusual heart tumours ( myelosarcoma ) this differential diagnosis should also be taken into consideration.

Cardiomyopathy, Dilated↗
PubMed1983

[Acute liver failure in abdominal Wilson's disease in early adulthood].

The acute abdominal form of Wilsons's disease was observed in three female patients aged 17, 18 and 30 years. Clinically uncharacteristic general symptoms and jaundice were dominant. Chemical pathology showed high bilirubin values with predominance of direct bilirubin, signs of hepatic and renal insufficiency and haemolytic anaemia. There were no neurologic symptoms and the Kayser-Fleischer ring was absent. Coeruloplasmin in blood was normal, copper concentration in blood and urine was clearly increased. Diagnosis of Wilsons's disease could only be established at post mortem by quantitative copper estimation in liver tissue. The patients succumbed 1--4 weeks after onset of symptoms through hepatic failure.

Acute Disease↗
PubMed1983

[Gastrointestinal tuberculosis--a diagnostic challenge].

Gastrointestinal tuberculosis has become a rare disease. Lesions are predominantly located in the ileocecal region, but all parts of intestinum can be involved. Occurrence in the esophagus is very rare. Protean manifestations often prevent an accurate diagnosis on time, especially if pulmonary symptoms are absent or misjudged. The further clinical course is determined by late complications of tuberculosis. We present 3 cases of gastrointestinal tuberculosis (two of esophagus, one of ileocecal region) in order to remind of this rare disease, which is associated with so many pitfalls.

Gastroscopy↗
PubMed1982

[Cardiovascular emergencies--endocrine and metabolic crises. Practical hints for the physician in emergency service].

50% of hospitalized medical emergency cases are cardiological and respiratory emergencies. Myocardial infarction, cardiogenic shock, ventricular arrhythmias and left ventricular failure often cause sudden death occurring within 1 or 2 hours. Therefore immediate management is necessary already in the prehospital phase of cardiovascular events. This does also apply for acute respiratory failure due to obstructive ventilatory disorders. Acute exacerbations of chronic obstructive pulmonary disease frequently are masked and may be misinterpreted as encephalopathy or alcohol withdrawal syndrome. Sedation may be dangerous. Also neuroglucopenic syndrome and hyperosmolar coma are occasionally interpreted wrongly. Thyrotoxic crisis, adrenal crisis and hypercalcemia are characterized by lethargy, mental disturbance and weakness, by dehydration, myopathy, nausea, constipation, diarrhea or tenesms or arrhythmias. In this situation of varied symptoms the most important action is to think of endocrine emergency, which may have multiple etiologies.

Airway Obstruction↗