Biomedical subjects

O Contreras Ortiz

Publications and source records attributed to O Contreras Ortiz.

6 recordsLinked to original sources

PubMed1996

Dynamic assessment of pelvic floor function in women using the intravaginal device test.

The aim of the study was to assess pelvic floor function and dysfunction using intravaginal devices (IVD test). One hundred and eighty-five patients were evaluated, 65 (35.1%) in the control group without genital prolapse and 120 (64.9%) in the study group, with prolapse. Anatomic changes were evaluated on a scale described by Halban, and functional classification based on palpation of the muscles of the pelvic floor during contraction. Additionally, weighted vaginal devices were used to assess pelvic floor function. Statistic analysis was performed with the Spearman-Pearson correlation coefficient, the chi2 test and the response/operator characteristic curve. There was an acceptable correlation between the IVD test and the functional classification of 0.75. Using this classification, the IVD test showed 86.58% sensitivity, 75.72% specificity, and had a positive predictive value of 73.95% and a negative predictive value of 87.64%. Significant differences between pelvic floor muscle activity in those patients with and without genital prolapse were observed (chi2 = 58.28, P=<0.005). It was concluded that pelvic floor assessment can be done through the evaluation of active muscle strength or pelvic floor integrity using the functional classification and the IVD test.

Adolescent↗

PubMed1994

[Deep pudendal reflex].

32 healthy women ranging from 20 to 68 years (51.84 +/- 10.36) were tested for Deep Pudendal Reflex (DPR). Dantec 13L40 (St. Mark's) superficial electrodes were used to pick up the responses of the external anal sphincter. These devices consist of a bipolar stimulating electrode mounted on the tip of the gloved index finger which is inserted into the rectum; 3 cm proximally at the base of the finger are recording electrodes which pick up the contraction response of the anal sphincter. To obtain the DPR the ischial spine is localized on transrectal examination and electrical stimuli given at that side, applying square stimulus of 0.2 ms duration and 0.5 Hz frequency. This stimulates the pudendal nerve as it leaves the pelvis through the greater sciatic notch, before it branches into the inferior rectal (to the anal sphincter) and perineal nerve (to the periurethral striated muscle). The conduction time was measured as the latency from the time of stimulation of the starting point of the reflex response curves. The shortest latency of various responses was accepted and measured in milliseconds (ms). The amplitudes of the responses were measured in microvolts (uv). We obtained reproducible DPR in all subjects. Mean latency was 36.18 +/- 4.29 ms; mean amplitude was 337.50 +/- 218.49 uv (Fig. 1, Table 2). DPR is a pudendal-anal reflex like the bulbo-cavernous reflex, but differs in latency, stimulation localization and afferent limb although both follow a common final afferent pathway.

Adult↗

PubMed1994

Pudendal reflexes in women with pelvic floor disorders.

The objective of this work was to study two pudendal anal reflexes: Deep Pudendal Reflex (DPR) and classical Bulbocavernosus Reflex (BCR) in women with primary and recurrent genital prolapse to obtain support to the hypothesis of pelvic nerve damage in patients with pelvic floor disorders. 124 women were studied: 68 were normal; 38 with genital prolapse (GP); and 18 with recurrent GP. Clinical and electrophysiological studies were carried out. Delayed reflex responses were found in 44/56 of patients (79%). [27/38 in genital prolapse group (71%); 17/18 in recurrent GP group (94%)]. The evaluation of pelvic floor reflex responses are tests to be taken into account in the diagnosis and management of pelvic floor disorders.

Adult↗

PubMed1993

Non-invasive diagnosis of bladder instability using the Bladder Instability Discriminant Index (BIDI).

The purpose of this study was to validate prospectively the BIDI index in the non-invasive diagnosis of bladder instability, as a procedure for clinical evaluation in primary health care of women. 217 patients were studied; 82 with stress incontinence, 39 with urge incontinence and 96 with both symptoms. All patients were studied by specialist physicians, who conducted a clinical evaluation, questionnaire, gynecological and urological examination, stress test, urodynamic assessment and a 7 day frequency/volume study, recording each intake and micturition; data that were used to calculate the BIDI index. The results obtained through the application of the BIDI were compared with the corresponding urodynamic diagnoses, achieving 88% sensitivity and 83% specificity. The use of the BIDI index is suggested as a non-invasive clinical diagnostic method, of low cost and simple performance. It is recommended for treatment control and for taking diagnostic and therapeutic decisions in medical centres lacking proper urodynamic equipment.

Adult↗

PubMed1988

Hormonal receptors in endometrial neoplasias.

The Authors studied the concentration of cytosolic and nuclear receptor for Estradiol and Progesterone in endometrial hyperplasia and carcinoma, compared with a control group. Comparative study of hormone receptor concentrations in different populations shows: 1) A significant increase in Estradiol receptors in endometrial hyperplasia (p less than 0.01); 2) A decreasing concentration of estradiol receptors with the decreasing of cellular differentiation in endometrial carcinoma (p less than 0.01); 3) A similar tendency and significance for Progesterone receptors; 4) For both receptors the tendency in the nuclear compartment is similar to that in cytosol but the significance is smaller (p less than 0.05).

Endometrial Hyperplasia↗

PubMed1988

Immunological changes in human breast cancer.

In 38 breast cancer patients were examined the following immune system parameters: total and active T lymphocytes; killer cells; bastogenic response to Phytohaemaglutinin; leucocyte migration inhibition test with autologous tumor extract; serum immunoglobulins and phagocytosis and intracellular killing of Candida albicans. The immunological evaluations were made in pre-surgery and after each 3 months, during 18 months. In stage I practically there was no difference with controls. The active T lymphocytes were significant decreased until 15 months post surgery in stage II and in all samples stages III and IV. The response to Phytohaemaglutinin was diminished in all samples of stages II, III and IV. A recognition and sensitiveness to tumoral antigen were observed until 6 months post surgery in stage I and during checking time in the others stages. Respect to the phagocytic function only the intracellular killing mechanism failed at 3 months post surgery.

Aged↗