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Biomedical subjects

O Creţu

Publications and source records attributed to O Creţu.

9 recordsLinked to original sources

[The rejection of a hepatic graft].

Hepatic graft rejection is an epiphenomenon of liver transplantation. Despite the immunosuppressive therapy, nowadays a level of 30-50% of acute rejection and 5-15% chronic rejection is always persisting. Graft rejection prophylaxis essentially represents the result of a subtle equilibrium of the chronic immunosuppression. This study presents the essential data concerning the graft rejection, such as: prevalences, classifications, clinical presentation and diagnostic, both anatomopathological and differential. Modern therapy of hepatic graft rejection is also presented.

Acute Disease↗

[A retrospective study of 83 patients hospitalized for a jaundice syndrome in the Surgical Clinic of Timişoara Municipal Hospital].

This is a retrospective study done on 83 patients admitted to surgical department of Timişoara Emergency Hospital in the period between 01/01/1992 and 31/03/1995; 47 patients were males, 36 females with mean age 56.1 years. All patients suffered from jaundice mainly conjugated hyperbilirubinemia. The causes of jaundice were: malignant tumours in 19 (22.9%), chronic diffuse parenchymatous liver disease in 24, stone common bile duct 22, benign biliary strictures and papillary stenosis in 6, extrinsic biliary compression and inflammation in 12. Surgery was done in 47 patients and medical treatment in 36 patients. During hospitalization, complications occurred in 19 patients. The condition of patients at discharge was considered: cured in 30, improved in 38, stationary in 2 and deteriorated in 12. Mortality occurred in one patient.

Adult↗

[Synchronous sigmoid and superior rectal resection and left hepatic lobectomy extended to Spiegel lobe for a sigmoid cancer with hepatic metastasis. Case report].

The recent developments of surgical technologies allowed the achievement of some standardized interventions with anatomical and functional visa, which based on the improvement of anesthesia and intensive care, and not least by elaboration of efficient chemotherapy protocols, determined new horizons in the treatment of advanced cancers. This work presents a case witch was hospitalized at the Department of Hepatic Surgery, of City Hospital from Timişoara for a colorectal cancer stage IV (T3N1M1), with hepatic metastasis localized at the left hepatic lobe (II and III segments) and Spiegel lobe. A surgical intervention was performed, when in the same operating time was practiced a sigmoid and superior rectal resection (Hartmann) and also a left hepatic lobotomy extended to the first segment. The post operating evolution of the patient was favorable and also after fourth month from the surgery, when no signs of relapse were established at reevaluation.

Adenocarcinoma↗

[The limits of surgery in the treatment of the icteric patients due to pancreatic head cancer].

Aim is to present the limits of surgery, determined by the dimension of the tumor and vascular invasion, in the treatment of the icteric patients with pancreatic head cancer. This paper is a retrospective study realized in Timisoara City Hospital, Surgery Clinic, on 68 patients, hospitalized for icteric syndrome due to pancreatic head cancer. Surgery was performed in 66 patients: 4 (6%) pancreaticoduodenectomy, Whipple modified technique, 62 (94%) palliative surgery which consists in a biliodigestive shunt associated with a gastroenterostomy, and 2 patients were not operated. In palliative treatment, 10 (15%) patients had complications and 3 (4.5%) died within 1 month after surgery. In the case of the patients with duodenopancreatectomy, there was no morbidity or mortality. Survival after one year was 0% in palliative treatment and 100% in pancreaticoduodenectomy. In icteric patients due to pancreatic head cancer, the possibility of pancreaticoduodenectomy without vascular resection is reduced (6%). Modified Whipple technique was imposed by the dimensions of the tumor (more than 3 cm) and vascular invasion, determining in the first place, the dissection of the vascular tree: portal, mesenteric, caval; and pancreaticoduodenectomy was performed only if there was no invasion.

Carcinoma↗

[Post-traumatic acute appendicitis in hernia's sac].

The paper presents two unusual pathological aspects of a hernia and an appendicitis. It is about a massive old inguinal hernia, with strangulation and an intra-saccular congestive acute appendicitis that occurred after a traumatic injury of the region. The presumptive diagnosis through a dynamic monitoring of the patient, clinical and biological analysis has made possible a favorable solution of the case.

Appendicitis↗

[Bronchoscopy in thoracic trauma].

Thoracic trauma often bears difficult problems of diagnosis and treatment. This paper reports 87 procedures on 20 severe thoracic injured patients, who have also suffered multiple injuries, to whom was performed bronchoscopy. These cases were regarding gender, age, traumatic cause, associated injuries and dynamic endo-bronchial aspect. There are detailed technique used in bronchoscopy and bronchoscopic suction, additional diagnostic procedures, technical tips, incidents and are also reported close and follow up results in these cases. We discuss indications of bronchoscopy and broncho-aspiration in thoracic trauma from diagnostic and treatment point of view. Conclusions underline major role of bronchoscopy in the management of severe thoracic trauma.

Adolescent↗

[Liver transplantation. I. Its history. The indications. Clinical efficacy].

The aim of this study is to present the actual indications of the liver transplantation in adult as well as in children patients. A multicenter comparative study based on the already published reports in Europe and in the United States has been done in order to analyse the survival rates for different liver diseases subjected to liver transplantation, as well as the prevalence of these nosologic entities in different hepato-biliary centers. Such an analysis is badly needed in Romania, where the prevalence of liver diseases is relatively high, and in the context of the initiation of transplantation in our country.

Adult↗