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O D Reva

Publications and source records attributed to O D Reva.

4 recordsLinked to original sources
PubMedDate not supplied

[Soluble neutral peptide hydrolases of nervous tissue].

Soluble forms of neutral peptide-hydrolases (protaminsulphate as a substrate) of the cat cerebral hemisphere grey and white matter were investigated by the method of gel-filtration on Sephadex G-150. The results of the experiments showed that grey and white matter of the cerebral hemispheres contains different forms of soluble neutral peptide-hydrolases. The products of protaminsulphate hydrolysis were analyzed by the method of gel-filtration as well (Sephadex G-25). Under the influence of the studied enzymes of protaminsulphate hydrolysis occurs due to subsequent splitting of C-terminal residues of arginine. It means that the studied soluble neutral peptide-hydrolases of grey and white matter of the cat cerebral hemisphere may be referred to the group of exopeptidases.

Animals↗
PubMedDate not supplied

[Effect of Triton-100 on activity and solubilization of brain acid proteinases].

The activity and solubilization of acid proteinases of grey and white matter of the cat great cerebral hemispheres were studied as affected by the detergent triton X-100. High concentrations of the detergent evoke a significant decrease of the activity in grey matter and significant increase--in white one. It is found that 20-25% of the activity of the grey matter acid proteinases are strongly bound with the studied tissues and not release under the effect of the detergent in high concentrations.

Animals↗