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O Delattre

Publications and source records attributed to O Delattre.

149 records · Page 9Linked to original sources
PubMedDate not supplied

Intraabdominal desmoplastic small round cell tumor: report of a case with fine needle aspiration, cytologic diagnosis and molecular confirmation.

BACKGROUND: Desmoplastic small round cell tumor (DSRCT) is a recently described neoplasm. This entity is well defined, with distinct clinical, pathologic and immunohistochemical features. Molecular studies have shown a specific reciprocal translocation t(11;22)(p13;q12). To our knowledge, no report of DSRCT with molecular confirmation on cytologic material has been reported before. CASE: Fine needle aspiration (FNA) was performed on an intraabdominal mass in a 37-year-old man. A May-Grunwald-Giemsa-stained preparation showed clusters of small round tumor cells associated with desmoplastic stromal cells, highly suggestive of DSRCT. FNA of a supraclavicular node showed cytologic features similar to those of the primary abdominal mass, including a prominent desmoplastic reaction of the stroma. Immunocytochemical studies showed myogenic and epithelial differentiation. Molecular analysis was performed on FNA, revealing the EWS/ WT1 chimeric transcript and thus confirming the cytologic diagnosis. CONCLUSION: Cytomorphologically, a definitive diagnosis of DSRCT may be difficult, as this tumor bears considerable resemblance to other small round cell tumors. The diagnosis can be confirmed by ancillary techniques, such as immunocytochemistry, and particularly by molecular analysis, which may also be performed on cytologic material.

Abdominal Neoplasms↗
PubMedDate not supplied

[Ocular complications of surgery of the spine. Proposal for a new head-rest].

Although severe ocular complications after spinal surgery are rarely reported in the orthopaedic literature, they are not uncommon. We studied 10 cases observed in 4 orthopaedic units to determine the types of complications and their mechanisms. It appears that the classic head-rest used to stabilise the position of the head and protection of the ocular globes during the operation have not fulfilled their functions correctly. An original head-rest is proposed together with preventive pre- and intraoperative measures which should be used in all procedures involving spinal surgery.

Adolescent↗